2023
Significant unfavorable geometrical changes in ascending aorta despite stable diameter at follow-up.
Kalogerakos P, Pirentis A, Papaharilaou Y, Skiadas C, Karantanas A, Mojibian H, Marketou M, Kochiadakis G, Elefteriades J, Lazopoulos G. Significant unfavorable geometrical changes in ascending aorta despite stable diameter at follow-up. Hellenic Journal Of Cardiology 2023 PMID: 37931701, DOI: 10.1016/j.hjc.2023.10.007.Peer-Reviewed Original ResearchBicuspid aortopathy does not require earlier surgical intervention
Zafar M, Wu J, Vinholo T, Li Y, Papanikolaou D, Ellauzi H, Ostberg N, Kalyanasundaram A, Kalogerakos P, Mukherjee S, Ziganshin B, Rizzo J, Elefteriades J. Bicuspid aortopathy does not require earlier surgical intervention. Journal Of Thoracic And Cardiovascular Surgery 2023, 168: 760-769.e4. PMID: 37088130, DOI: 10.1016/j.jtcvs.2023.04.017.Peer-Reviewed Original ResearchBicuspid aortic valveAdverse aortic eventsEvent-free survivalAortic eventsAortic sizeAortic diameterAortic growth rateEarly surgical interventionLong-term complicationsRisk of complicationsThoracic aortic aneurysmAortic deathComplication rateSurgical repairOperative repairProphylactic surgerySurgical interventionAortic aneurysmAortic valveSurgical correctionBicuspid aortopathyRelative riskExpert centersTAV-ATAAPatientsAortic Size at the Time of Type A and Type B Dissections
Perez Z, Zafar M, Velasco J, Sonsino A, Ellauzi H, John C, Kalyanasundaram A, Ziganshin B, Elefteriades J. Aortic Size at the Time of Type A and Type B Dissections. The Annals Of Thoracic Surgery 2023, 116: 262-268. PMID: 37062339, DOI: 10.1016/j.athoracsur.2023.03.037.Peer-Reviewed Original ResearchConceptsType B dissectionTime of dissectionB dissectionAortic sizeAortic diameterBicuspid aortic valveThoracic aortic aneurysmAortic interventionAortic dissectionSurgical interventionAortic aneurysmFemale sexAortic valveThoracic aortaProphylactic repairUnadjusted regressionLeft shiftLogistic regressionDissectionNew guidelinesType ASize criteriaOddsInterventionTime of types
2022
The Genetics of Inheritable Aortic Diseases
Kalyanasundaram A, Elefteriades J. The Genetics of Inheritable Aortic Diseases. Current Cardiovascular Risk Reports 2022, 16: 13-24. DOI: 10.1007/s12170-022-00687-x.Peer-Reviewed Original ResearchAbdominal aortic aneurysmRisk factorsAortic diseaseAortic aneurysmPatient outcomesGene variantsTraditional cardiovascular risk factorsBetter long-term survivalCV risk factorsDevelopment of TAADCardiovascular risk factorsBetter patient outcomesLong-term survivalGeneral risk factorsPurpose of ReviewOverTGF-β pathwayEarly surgeryLipid metabolism pathwaysDefinitive treatmentAneurysmal diseaseAortic diameterProphylactic surgeryAggressive casesPatient-specific guidelinesAortic wall
2011
Epidemiology and Natural History of Thoraco-Abdominal Aortic Aneurysms
Stein L, Elefteriades J. Epidemiology and Natural History of Thoraco-Abdominal Aortic Aneurysms. 2011, 25-32. DOI: 10.1007/978-88-470-1857-0_3.Peer-Reviewed Original ResearchThoracic aortic aneurysmAortic aneurysmThoraco-abdominal aortic aneurysmChronic obstructive pulmonary diseaseObstructive pulmonary diseaseSmooth muscle cellsTAAA rupturePulmonary diseaseTertiary centerAortic diameterTAAANatural historyAneurysm growthMuscle cellsOptimal timingAneurysmsPresent unique challengesRiskBetter identificationRupture increasesHypertensionSmokingPatientsDerangementUnique challenges
1998
Penetrating ulcer of the thoracic aorta: What is it? How do we recognize it? How do we manage it?
Coady M, Rizzo J, Hammond G, Pierce J, Kopf G, Elefteriades J. Penetrating ulcer of the thoracic aorta: What is it? How do we recognize it? How do we manage it? Journal Of Vascular Surgery 1998, 27: 1006-1016. PMID: 9652462, DOI: 10.1016/s0741-5214(98)70003-5.Peer-Reviewed Original ResearchConceptsAortic dissectionOptimal treatmentThoracic aortaNatural historyType AType B aortic dissectionB aortic dissectionClassic aortic dissectionLarger aortic diametersAortic ulcerAtherosclerotic ulcerAortic ruptureClinical featuresInitial diagnosisInitial presentationIntraoperative findingsRetrospective reviewSurgical managementAortic diameterRadiologic signsTomographic scanPathology reportsUlcersPatientsAorta