Perfusion abnormalities and decision making in cocaine dependence
Tucker KA, Potenza MN, Beauvais JE, Browndyke JN, Gottschalk PC, Kosten TR. Perfusion abnormalities and decision making in cocaine dependence. Biological Psychiatry 2004, 56: 527-530. PMID: 15450790, DOI: 10.1016/j.biopsych.2004.06.031.Peer-Reviewed Original ResearchConceptsIowa Gambling TaskFrontal gyrusCocaine-dependent patientsPoor decision-making abilitiesBetter IGT performanceCard selectionAbstinent cocaine-dependent patientsMiddle frontal gyrusMedial frontal gyrusSuperior frontal gyrusDecision-making abilityAnterior cingulate gyrusCognitive factorsGambling TaskResponse inhibitionCognitive functioningIGT performanceImpaired performanceIGT scoresSeverity of impairmentCingulate gyrusBrain regionsGyrusCocaine dependenceCocaine abusersExamining the Effect of Cerebral Perfusion Abnormality Magnitude on Cognitive Performance in Recently Abstinent Chronic Cocaine Abusers
Browndyke J, Tucker K, Woods S, Beauvais J, Cohen R, Gottschalk P, Kosten T. Examining the Effect of Cerebral Perfusion Abnormality Magnitude on Cognitive Performance in Recently Abstinent Chronic Cocaine Abusers. Journal Of Neuroimaging 2004, 14: 162-169. PMID: 15095563, DOI: 10.1111/j.1552-6569.2004.tb00234.x.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultCerebral CortexCocaineCocaine-Related DisordersCognition DisordersFemaleHumansImage Processing, Computer-AssistedMaleNeuropsychological TestsPsychometricsReference ValuesRegional Blood FlowReproducibility of ResultsSubstance Withdrawal SyndromeTechnetium Tc 99m ExametazimeTomography, Emission-Computed, Single-PhotonConceptsCognitive performanceComplex attentionSubstance abuse populationNeuropsychological impairmentAbuse populationCocaine abusersNeuropsychological assessment batteryMotor speedAbstinent cocaine abusersExecutive functioningExecutive skillsNeuropsychological functioningStatistical parametric mapping techniquesNeuropsychological performanceAbuse sampleAssessment BatterySPECT data analysisCognitive deficitsAssessment measuresMotor performanceChronic cocaine abusersManual dexterityGroup comparisonsChronic cocaineMemory