2024
Learning implementation of a guideline based decision support system to improve hypertension treatment in primary care in China: pragmatic cluster randomised controlled trial
Song J, Wang X, Wang B, Ge Y, Bi L, Jing F, Jin H, Li T, Gu B, Wang L, Hao J, Zhao Y, Liu J, Zhang H, Li X, Li J, Ma W, Wang J, Normand S, Herrin J, Armitage J, Krumholz H, Zheng X. Learning implementation of a guideline based decision support system to improve hypertension treatment in primary care in China: pragmatic cluster randomised controlled trial. The BMJ 2024, 386: e079143. PMID: 39043397, PMCID: PMC11265211, DOI: 10.1136/bmj-2023-079143.Peer-Reviewed Original ResearchConceptsClinical decision support systemsPrimary care practicesElectronic health recordsIntervention groupSystolic blood pressurePrimary careCare practicesBlood pressure <Health recordsPragmatic cluster randomised controlled trialCluster randomised controlled trialImproving hypertension treatmentPrimary care settingBlood pressure control ratesBlood pressureProportion of visitsProportion of participantsRandomised controlled trialsSystolic blood pressure <Control groupInjurious fallsRelated visitsCare settingsDiastolic blood pressure <Follow-up
2021
Uptake of evidence by physicians: De-adoption of erythropoiesis-stimulating agents after the TREAT trial
Vu K, Zhou J, Everhart A, Desai N, Herrin J, Jena AB, Ross JS, Shah ND, Karaca-Mandic P. Uptake of evidence by physicians: De-adoption of erythropoiesis-stimulating agents after the TREAT trial. BMC Nephrology 2021, 22: 284. PMID: 34419007, PMCID: PMC8379779, DOI: 10.1186/s12882-021-02491-y.Peer-Reviewed Original ResearchConceptsErythropoiesis-stimulating agentsChronic kidney diseaseEpoetin alfaDarbepoetin alfaTREAT trialTypes of ESAsNew clinical evidencePrimary care physiciansMedicare AdvantageUptake of evidenceCare physiciansAnemia treatmentClinical evidenceKidney diseasePhysician genderMedicare feeUnsafe treatmentSegmented regression approachStudy periodPhysiciansService populationConsistent changesAlfaHigher useTreatmentPhysician variation in the de‐adoption of ineffective statin and fibrate therapy
Everhart A, Desai NR, Dowd B, Herrin J, Higuera L, Jeffery MM, Jena AB, Ross JS, Shah ND, Smith LB, Karaca‐Mandic P. Physician variation in the de‐adoption of ineffective statin and fibrate therapy. Health Services Research 2021, 56: 919-931. PMID: 33569804, PMCID: PMC8522575, DOI: 10.1111/1475-6773.13630.Peer-Reviewed Original ResearchMeSH KeywordsAgedDiabetes Mellitus, Type 2Drug Therapy, CombinationDrug UtilizationFemaleFibric AcidsGuideline AdherenceHumansHydroxymethylglutaryl-CoA Reductase InhibitorsHypoglycemic AgentsHypolipidemic AgentsLongitudinal StudiesMaleMedicare Part CMiddle AgedPractice Guidelines as TopicPractice Patterns, Physicians'Risk FactorsUnited StatesConceptsMedicare Advantage patientsType 2 diabetic patientsACCORD lipid trialFibrate useAdvantage patientsCommercial patientsPhysician characteristicsLIPID trialFibrate therapyDiabetic patientsPhysician variationDiabetes careType 2 diabetes diagnosisContinuous insurance enrollmentPatient diabetes carePhysician random effectsGlucose-lowering drugsElectronic health record dataHealth record dataReal-world data assetConcurrent statinCardiovascular eventsStatin usersClinical evidenceManagement visits
2019
Follow-up Care for Breast Cancer Survivors
Ruddy KJ, Herrin J, Sangaralingham L, Freedman RA, Jemal A, Haddad TC, Allen SV, Hieken T, Boughey JC, Ganz PA, Havyer RD, Shah ND. Follow-up Care for Breast Cancer Survivors. Journal Of The National Cancer Institute 2019, 112: 111-113. PMID: 31613369, PMCID: PMC7849972, DOI: 10.1093/jnci/djz203.Peer-Reviewed Original ResearchMeSH KeywordsAftercareBreast NeoplasmsCancer SurvivorsDisease ManagementFemaleHumansPractice Guidelines as TopicPublic Health SurveillanceRegistriesRetrospective StudiesConceptsBreast cancer survivorsCancer survivorsUS commercial insurance databaseCurative-intent surgeryCommercial insurance databasePrimary care providersEndocrine therapyIntent surgeryImpairs outcomeSurvivorship guidelinesInsurance databaseNonwhite raceAnnual followBreast cancerCare providersClaims dataClinical practiceOlder ageSurgeryWomenSurvivorsYear 2ChemotherapyPatientsOncologists
2016
Impact of Prostate-specific Antigen (PSA) Screening Trials and Revised PSA Screening Guidelines on Rates of Prostate Biopsy and Postbiopsy Complications
Gershman B, Van Houten HK, Herrin J, Moreira DM, Kim SP, Shah ND, Karnes RJ. Impact of Prostate-specific Antigen (PSA) Screening Trials and Revised PSA Screening Guidelines on Rates of Prostate Biopsy and Postbiopsy Complications. European Urology 2016, 71: 55-65. PMID: 26995328, DOI: 10.1016/j.eururo.2016.03.015.Peer-Reviewed Original ResearchConceptsRate of biopsyProstate-specific antigen (PSA) screeningPredictors of complicationsPostbiopsy complicationsUSPSTF recommendationsAntigen screeningProstate biopsyRelative morbidityScreening TrialUS Preventive Services Task Force (USPSTF) recommendationOvarian Cancer Screening TrialAmerican Urological Association guidelinesMorbidity of biopsyPrior fluoroquinolone useEuropean Randomized StudyCancer Screening TrialInterrupted time series analysisProportion of menTask Force recommendationsInfectious complicationsAnticoagulant useComplication rateUnderwent biopsyRandomized studyScreening guidelines
2013
HIV Screening Practices and Hospital Characteristics in the U.S., 2009–2010
Herrin J, Wesolowski LG, Heffelfinger JD, Bostick N, Hall HI, Ethridge SF, Branson BM. HIV Screening Practices and Hospital Characteristics in the U.S., 2009–2010. Public Health Reports 2013, 128: 161-169. PMID: 23633731, PMCID: PMC3610068, DOI: 10.1177/003335491312800306.Peer-Reviewed Original ResearchConceptsHospital characteristicsU.S. health care settingsMultivariate logistic regression analysisHIV screening practicesUndiagnosed HIV infectionHIV testing practicesNational hospital surveyLogistic regression analysisHealth care settingsType of hospitalCharacteristics of hospitalsAreas of prevalenceHIV screeningHIV infectionMultivariable analysisHIV prevalenceScreening practicesTeaching hospitalAnnual admissionsMedicaid patientsHospital SurveyPatientsHospitalBivariate analysisDisease control
2011
How Good Are the Data? Feasible Approach to Validation of Metrics of Quality Derived From an Outpatient Electronic Health Record
Benin AL, Fenick A, Herrin J, Vitkauskas G, Chen J, Brandt C. How Good Are the Data? Feasible Approach to Validation of Metrics of Quality Derived From an Outpatient Electronic Health Record. American Journal Of Medical Quality 2011, 26: 441-451. PMID: 21926280, DOI: 10.1177/1062860611403136.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAmbulatory CareChildChild, PreschoolGuideline AdherenceHumansInfantMass ScreeningMedical Records Systems, ComputerizedOutcome and Process Assessment, Health CareOutpatientsPatient SafetyPediatricsPractice Guidelines as TopicQuality Indicators, Health CareQuality of Health CareReproducibility of Results
2005
Hospital Improvement in Time to Reperfusion in Patients With Acute Myocardial Infarction, 1999 to 2002
McNamara RL, Herrin J, Bradley EH, Portnay EL, Curtis JP, Wang Y, Magid DJ, Blaney M, Krumholz HM, Investigators N. Hospital Improvement in Time to Reperfusion in Patients With Acute Myocardial Infarction, 1999 to 2002. Journal Of The American College Of Cardiology 2005, 47: 45-51. PMID: 16386663, PMCID: PMC1475926, DOI: 10.1016/j.jacc.2005.04.071.Peer-Reviewed Original ResearchConceptsST-segment elevation myocardial infarctionBalloon timeMin/yearNeedle timeMyocardial infarctionHospital characteristicsAcute ST-segment elevation myocardial infarctionPercutaneous coronary intervention cohortPercutaneous coronary intervention volumeElevation myocardial infarctionPercutaneous coronary interventionRetrospective observational studyFour-year study periodRapid reperfusionCoronary interventionFibrinolytic therapyHospital arrivalTherapy cohortReperfusion timeIntervention cohortNational registryIntervention volumeObservational studyHospital improvementPatients
2002
The relation between methods and recommendations in clinical practice guidelines for hypertension and hyperlipidemia.
Fretheim A, Williams JW, Oxman AD, Herrin J. The relation between methods and recommendations in clinical practice guidelines for hypertension and hyperlipidemia. The Journal Of Family Practice 2002, 51: 963-8. PMID: 12485552.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedEvaluation Studies as TopicEvidence-Based MedicineFamily PracticeFemaleGuideline AdherenceHealth Planning GuidelinesHumansHyperlipidemiasHypertensionMaleMiddle AgedPractice Guidelines as TopicPractice Patterns, Physicians'Quality of Health CareRisk AssessmentSensitivity and SpecificitySeverity of Illness IndexVirginiaConceptsClinical practice guidelinesPractice guidelinesDrug selectionTreatment thresholdSpecialty societiesInitial drug selectionCholesterol screeningGuideline developersSystematic reviewHypertensionHyperlipidemiaAggressive recommendationsGuidelinesWide variationGuideline methodsRecommendationsCriteriaCluster randomised controlled trial of tailored interventions to improve the management of urinary tract infections in women and sore throat
Flottorp S, Oxman A, Håvelsrud K, Treweek S, Herrin J. Cluster randomised controlled trial of tailored interventions to improve the management of urinary tract infections in women and sore throat. The BMJ 2002, 325: 367. PMID: 12183309, PMCID: PMC117890, DOI: 10.1136/bmj.325.7360.367.Peer-Reviewed Original ResearchConceptsUrinary tract infectionTract infectionsSore throatTelephone consultationsThroat groupUrinary tract infection groupLaboratory testsAntibiotic prescriptionsPatient educational materialsRate of useInfection groupGeneral practitionersIntervention groupPractice assistantsOutcome measuresGeneral practiceComplex interventionsInfectionInterventionWomenSignificant differencesConsultationTrialsThroatAntibioticsA Call for Action
Scheel I, Hagen K, Herrin J, Oxman A. A Call for Action. Spine 2002, 27: 561-566. PMID: 11884902, DOI: 10.1097/00007632-200203150-00002.Peer-Reviewed Original ResearchConceptsLow back painGeneral practitionersBack painPassive interventionSick leaveBack pain patientsClinical practice guidelinesMain outcome measuresProactive interventionsEligible patientsPain patientsIntervention municipalitiesEarly returnGP practicesPractice guidelinesBACKGROUND DATAOutcome measuresPatientsControl groupPainTelephone callsCommunity interventionsControl municipalitiesInterventionImportance of advice
2000
Implementing clinical guidelines in the treatment of hypertension.
Herrin J, Flottorp S. Implementing clinical guidelines in the treatment of hypertension. Scandinavian Journal Of Primary Health Care 2000, 18: 61-3. PMID: 10811048.Peer-Reviewed Original Research
1997
Effect of panel composition on physician ratings of appropriateness of abdominal aortic aneurysm surgery: elucidating differences between multispecialty panel results and specialty society recommendations
Herrin J, Etchason J, Kahan J, Brook R, Ballard D. Effect of panel composition on physician ratings of appropriateness of abdominal aortic aneurysm surgery: elucidating differences between multispecialty panel results and specialty society recommendations. Health Policy 1997, 42: 67-81. PMID: 10173494, DOI: 10.1016/s0168-8510(97)00055-9.Peer-Reviewed Original ResearchConceptsAbdominal aortic aneurysm surgeryAortic aneurysm surgeryVascular surgeonsAneurysm surgeryPhysician panelAbdominal aortic aneurysm managementAortic aneurysm managementSpecialty society recommendationsSpecialty societiesSame surgerySociety recommendationsVascular surgeryNorth American ChapterPhysician ratingsCardiovascular surgeryClinical appropriatenessAneurysm managementExpert panel membersSurgerySurgeon rankingsRAND panelSurgeonsConcurrent guidelinesPhysiciansNecessity ratings