2000
The Cutaneous Microcirculation
Braverman I. The Cutaneous Microcirculation. Journal Of Investigative Dermatology Symposium Proceedings 2000, 5: 3-9. PMID: 11147672, DOI: 10.1046/j.1087-0024.2000.00010.x.Peer-Reviewed Original ResearchConceptsLaser Doppler flowmetryDermal-subcutaneous junctionRed cell fluxDoppler flowmetryCutaneous microcirculationAscending arteriolesMicrovascular segmentsCell fluxHorizontal plexusLight microscopic featuresSmooth muscle cellsUpper horizontal plexusNormal physiologic stateRed blood cellsPapillary loopsPathogenetic mechanismsSkin biopsiesMicrovascular elementsSkin circulationSkin disordersMuscle cellsRetrograde flowArteriolesFlowmetryBlood cells
1997
The Cutaneous Microcirculation: Ultrastructure and Microanatomical Organization
Braverman I. The Cutaneous Microcirculation: Ultrastructure and Microanatomical Organization. Microcirculation 1997, 4: 329-340. PMID: 9329009, DOI: 10.3109/10739689709146797.Peer-Reviewed Original ResearchConceptsLaser Doppler flowmetryDermal-subcutaneous junctionRed cell fluxCutaneous microcirculationAscending arteriolesMicrovascular segmentsSkin biopsy specimensCell fluxHorizontal plexusLight microscopic featuresSmooth muscle cellsUpper horizontal plexusNormal physiological stateRed blood cellsPapillary loopsBiopsy specimensPathogenetic mechanismsDoppler flowmetryMicrovascular elementsSkin circulationSkin disordersAbility of LDFMuscle cellsRetrograde flowArterioles
1996
Additional courses of total skin electron beam therapy in the treatment of patients with recurrent cutaneous T-cell lymphoma
Wilson L, Quiros P, Kolenik S, Heald P, Braverman I, Edelson R, Kacinski B. Additional courses of total skin electron beam therapy in the treatment of patients with recurrent cutaneous T-cell lymphoma. Journal Of The American Academy Of Dermatology 1996, 35: 69-73. PMID: 8682967, DOI: 10.1016/s0190-9622(96)90499-5.Peer-Reviewed Original ResearchConceptsTotal skin electron beam therapyCutaneous T-cell lymphomaRecurrent cutaneous T-cell lymphomaComplete responseT-cell lymphomaElectron beam therapySecond courseMedian disease-free intervalThird courseAdditional coursesBeam therapyDisease-free intervalTreatment of patientsAcceptable risk profileForm of therapyMedian doseMedian survivalMild erythemaPatientsInitial courseTherapyVariety of modalitiesRisk profileEntire groupLocalized radiationRegional vs Systemic Responses to Mental Stress: A Potential Mechanism for Non-Demand-Related Ischemia
Silverman D, Jotkowitz A, Gutter V, Braverman I, O'Connor T. Regional vs Systemic Responses to Mental Stress: A Potential Mechanism for Non-Demand-Related Ischemia. Microvascular Research 1996, 51: 396-399. PMID: 8992237, DOI: 10.1006/mvre.1996.0036.Peer-Reviewed Original Research
1995
Hypopigmented variant of mycosis fungoides: Demography, histopathology, and treatment of seven cases
Lambroza E, Cohen S, Phelps R, Lebwohl M, Braverman I, DiCostanzo D. Hypopigmented variant of mycosis fungoides: Demography, histopathology, and treatment of seven cases. Journal Of The American Academy Of Dermatology 1995, 32: 987-993. PMID: 7751470, DOI: 10.1016/0190-9622(95)91337-8.Peer-Reviewed Original ResearchConceptsMycosis fungoidesEpidermal atrophyVariant of MFTreatment of choiceMedian ageMononuclear cellsHistologic findingsBiopsy diagnosisComplete repigmentationDisease onsetTreatment outcomesMF variantDisease processNew casesYoung populationPrior reportsFungoidesPUVAPatientsAtrophyMicroscopic featuresHistopathologyTreatmentDark skinSkin
1994
Inducibility and Expression of Microvascular Endothelial Adhesion Molecules in Lesional, Perilesional, and Uninvolved Skin of Psoriatic Patients
Petzelbauer P, Pober J, Keh A, Braverman I. Inducibility and Expression of Microvascular Endothelial Adhesion Molecules in Lesional, Perilesional, and Uninvolved Skin of Psoriatic Patients. Journal Of Investigative Dermatology 1994, 103: 300-305. PMID: 7521374, DOI: 10.1111/1523-1747.ep12394720.Peer-Reviewed Original ResearchConceptsVascular cell adhesion molecule-1Endothelial leukocyte adhesion molecule-1Lesional skinAdhesion molecule-1Psoriatic patientsEndothelial cellsUninvolved skinPerilesional skinMolecule-1Dermal microvasculatureCapillary loopsCell adhesion molecule-1Perivascular inflammatory infiltratesLeukocyte adhesion molecule-1VCAM-1 expressionTumor necrosis factorEndothelial adhesion moleculesMicrovascular endothelial cellsEndothelial cell expressionVenular endothelial cellsInflammatory infiltrateEpidermal involvementPsoriatic plaquesSuperficial plexusNecrosis factorSpatial Heterogeneity in Normal Skin Perfusion Recorded with Laser Doppler Imaging and Flowmetry
Wardell K, Braverman I, Silverman D, Nilsson G. Spatial Heterogeneity in Normal Skin Perfusion Recorded with Laser Doppler Imaging and Flowmetry. Microvascular Research 1994, 48: 26-38. PMID: 7990721, DOI: 10.1006/mvre.1994.1036.Peer-Reviewed Original ResearchImpact of non-CTCL dermatologic diagnoses and adjuvant therapies on cutaneous T-cell lymphoma patients treated with total skin electron beam radiation therapy
Wilson L, Cooper D, Goodrich A, Friedman N, Feldman A, Braverman I, Kacinski B. Impact of non-CTCL dermatologic diagnoses and adjuvant therapies on cutaneous T-cell lymphoma patients treated with total skin electron beam radiation therapy. International Journal Of Radiation Oncology • Biology • Physics 1994, 28: 829-837. PMID: 8138435, DOI: 10.1016/0360-3016(94)90102-3.Peer-Reviewed Original ResearchConceptsTotal skin electron beam therapySystemic adjuvant therapyRelapse-free survivalDoxorubicin/cyclophosphamide chemotherapyShorter relapse-free survivalElectron beam therapyAdjuvant therapyDermatologic diagnosesBeam therapyCyclophosphamide chemotherapyFollicular mucinosisOverall survivalT2 patientsExtracorporeal photopheresisLymphomatoid papulosisCutaneous relapseTotal skin electron beam radiation therapyCutaneous T-cell lymphoma patientsT-cell lymphoma patientsBetter relapse-free survivalClinical complete responseCohort of patientsElectron beam radiation therapyBeam radiation therapyAdjuvant chemotherapy
1992
Human dermatosparaxis: a form of Ehlers-Danlos syndrome that results from failure to remove the amino-terminal propeptide of type I procollagen.
Smith L, Wertelecki W, Milstone L, Petty E, Seashore M, Braverman I, Jenkins T, Byers P. Human dermatosparaxis: a form of Ehlers-Danlos syndrome that results from failure to remove the amino-terminal propeptide of type I procollagen. American Journal Of Human Genetics 1992, 51: 235-44. PMID: 1642226, PMCID: PMC1682688.Peer-Reviewed Original ResearchConceptsAmino-terminal propeptideFragile skinType IConnective tissue disordersEhlers-Danlos syndromeLax jointsType VIIAffected animalsSkinChildrenCultured fibroblastsNormal cellsEhlers-Danlos syndrome type VIIPro alphaDisordersPropeptideAlphaDermatosparaxisProteolytic processingSepsisN-proteinaseCellsSyndromeCollagen fibrilsSynchronous vasomotion in the human cutaneous microvasculature provides evidence for central modulation
Schechner J, Braverman I. Synchronous vasomotion in the human cutaneous microvasculature provides evidence for central modulation. Microvascular Research 1992, 44: 27-32. PMID: 1640877, DOI: 10.1016/0026-2862(92)90099-b.Peer-Reviewed Original ResearchTopographic mapping of the cutaneous microcirculation using two outputs of laser-Doppler flowmetry: Flux and the concentration of moving blood cells
Braverman I, Schechner J, Silverman D, Keh-Yen A. Topographic mapping of the cutaneous microcirculation using two outputs of laser-Doppler flowmetry: Flux and the concentration of moving blood cells. Microvascular Research 1992, 44: 33-48. PMID: 1640878, DOI: 10.1016/0026-2862(92)90100-4.Peer-Reviewed Original ResearchConceptsUpper plexusLaser Doppler flowmetryCutaneous microcirculationTrephine biopsyVascular unitAvascular zoneAscending arteriolesVascular patternMicrovascular areaPlexusBlood cellsUpper thirdFlexor forearmSerial sectionsLaser Doppler instrumentArteriolesForearmPeripheral partCMBCPhysiological studiesSubjectsCell outputBiopsyFlowmetryMicrocirculation
1991
Contour Mapping of the Cutaneous Microvasculature by Computerized Laser Doppler Velocimetry
Braverman I, Schechner J. Contour Mapping of the Cutaneous Microvasculature by Computerized Laser Doppler Velocimetry. Journal Of Investigative Dermatology 1991, 97: 1013-1018. PMID: 1748811, DOI: 10.1111/1523-1747.ep12492255.Peer-Reviewed Original Research
1990
Ultrastructure and Three-Dimensional Organization of the Telangiectases of Hereditary Hemorrhagic Telangiectasia
Braverman I, Keh A, Jacobson B. Ultrastructure and Three-Dimensional Organization of the Telangiectases of Hereditary Hemorrhagic Telangiectasia. Journal Of Investigative Dermatology 1990, 95: 422-427. PMID: 2212727, DOI: 10.1111/1523-1747.ep12555569.Peer-Reviewed Original ResearchCorrelation of Laser Doppler Wave Patterns with Underlying Microvascular Anatomy
Braverman I, Keh A, Goldminz D. Correlation of Laser Doppler Wave Patterns with Underlying Microvascular Anatomy. Journal Of Investigative Dermatology 1990, 95: 283-286. PMID: 2143522, DOI: 10.1111/1523-1747.ep12484917.Peer-Reviewed Original ResearchUltrastructural Analysis of the Endothelial-Pericyte Relationship in Diabetic Cutaneous Vessels
Braverman I, Sibley J, Keh A. Ultrastructural Analysis of the Endothelial-Pericyte Relationship in Diabetic Cutaneous Vessels. Journal Of Investigative Dermatology 1990, 95: 147-153. PMID: 2380575, DOI: 10.1111/1523-1747.ep12477903.Peer-Reviewed Original ResearchUltrastructural and Three-Dimensional Analysis of the Contractile Cells of the Cutaneous Microvasculature
Braverman I, Sibley J. Ultrastructural and Three-Dimensional Analysis of the Contractile Cells of the Cutaneous Microvasculature. Journal Of Investigative Dermatology 1990, 95: 90-96. PMID: 2366005, DOI: 10.1111/1523-1747.ep12874034.Peer-Reviewed Original Research
1989
Skin changes in menopause
Bolognia J, Braverman I, Rousseau M, Sarrel P. Skin changes in menopause. Maturitas 1989, 11: 295-304. PMID: 2693917, DOI: 10.1016/0378-5122(89)90026-1.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsMenopausal womenEstrogen replacement therapyElastic fibersAge-related ultrastructural changesSun-exposed skinSun-protected skinDermal elastic fibersCutaneous signsEstrogen deprivationPremature menopauseReplacement therapySkin changesSkin signsTreatment periodCystic spacesDegenerative changesGranular degenerationSymptomsUltrastructural changesWomenMenopauseSignificant differencesPatientsPremature agingSkinAngiogenic properties of normal and psoriatic skin associate with epidermis, not dermis.
Malhotra R, Stenn K, Fernandez L, Braverman I. Angiogenic properties of normal and psoriatic skin associate with epidermis, not dermis. Laboratory Investigation 1989, 61: 162-5. PMID: 2474089.Peer-Reviewed Original ResearchConceptsPsoriatic patientsPsoriatic plaque skinInflammatory cellsVascular proliferationPsoriatic lesionsPsoriatic skinNormal subjectsSkin diseasesDay 2Nonpsoriatic skinNormal skinPatient's skinAngiogenic activityAngiogenic stimuliVessel growthAngiogenic propertiesDermisNew vesselsAngiogenic assaysSkinPsoriasisVessel formationPatientsEpidermal growthLesionsUltrastructure and organization of the cutaneous microvasculature in normal and pathologic states.
Braverman I. Ultrastructure and organization of the cutaneous microvasculature in normal and pathologic states. Journal Of Investigative Dermatology 1989, 93: 2s-9s. PMID: 2666519, DOI: 10.1111/1523-1747.ep12580893.Peer-Reviewed Original ResearchUltrastructure and Organization of the Cutaneous Microvasculature in Normal and Pathologic States
Braverman I. Ultrastructure and Organization of the Cutaneous Microvasculature in Normal and Pathologic States. Journal Of Investigative Dermatology 1989, 93: s2-s9. DOI: 10.1038/jid.1989.2.Peer-Reviewed Original Research