2024
Disentangling negative and positive symptoms in schizophrenia and autism spectrum disorder
Corbera S, Wexler B, Bell M, Pittman B, Pelphrey K, Pearlson G, Assaf M. Disentangling negative and positive symptoms in schizophrenia and autism spectrum disorder. Schizophrenia Research 2024, 271: 1-8. PMID: 39002525, PMCID: PMC11384336, DOI: 10.1016/j.schres.2024.07.002.Peer-Reviewed Original ResearchAutism spectrum disorderPositive and Negative Syndrome ScaleAutism Diagnostic Observation Schedule-GenericExperiential negative symptomsPositive symptomsNegative symptomsExploratory factor analysisSpectrum disorderNegative Syndrome ScaleTarget negative symptomsSyndrome ScaleDiscriminant function analysisSZ relativesAssociated with quality of lifeSchizophreniaSocial skillsSocial functioningDiagnostic classificationAutismFactor analysisAssociated with qualityPredictor of diagnosisSymptomsDisordersQuality of lifeDouble Functionally Independent Primitives Provide Disorder Specific Fingerprints of Mental Illnesses
Soleimani N, Pearlson G, Iraji A, Calhoun V. Double Functionally Independent Primitives Provide Disorder Specific Fingerprints of Mental Illnesses. 2024, 00: 1-4. DOI: 10.1109/isbi56570.2024.10635116.Peer-Reviewed Original ResearchAutism spectrum disorderMental illnessBipolar disorderMental disordersManifestations of mental illnessAssociated with mental illnessFunctional network connectivityFunctional network connectivity patternsNetwork connectivity patternsDisorder-specificDepressive disorderNeural underpinningsSpectrum disorderPsychological disordersNeuroimaging techniquesConnectivity patternsDisordersSchizophreniaHealthy controlsIllnessBrainFunctional changesMDDAutismNetwork connectivity
2023
Intrinsic neural timescales in autism spectrum disorder and schizophrenia. A replication and direct comparison study
Uscătescu L, Kronbichler M, Said-Yürekli S, Kronbichler L, Calhoun V, Corbera S, Bell M, Pelphrey K, Pearlson G, Assaf M. Intrinsic neural timescales in autism spectrum disorder and schizophrenia. A replication and direct comparison study. Schizophrenia 2023, 9: 18. PMID: 36997542, PMCID: PMC10063601, DOI: 10.1038/s41537-023-00344-1.Peer-Reviewed Original ResearchIntrinsic neural timescalesPatient groupBrain areasLeft lateral occipital gyrusRight post-central gyrusAutism spectrum disorderNeural timescalesPost-central gyrusLateral occipital gyrusDirect comparison studiesSpectrum disorderOccipital gyrusSymptom severitySchizophreniaGroup differencesGyrusDisordersPresent studyGroupSeverityPeripheral inflammation is associated with impairments of inhibitory behavioral control and visual sensorimotor function in psychotic disorders
Zhang L, Lizano P, Xu Y, Rubin L, Lee A, Lencer R, Reilly J, Keefe R, Keedy S, Pearlson G, Clementz B, Keshavan M, Gershon E, Tamminga C, Sweeney J, Hill S, Bishop J. Peripheral inflammation is associated with impairments of inhibitory behavioral control and visual sensorimotor function in psychotic disorders. Schizophrenia Research 2023, 255: 69-78. PMID: 36965362, PMCID: PMC10175233, DOI: 10.1016/j.schres.2023.03.030.Peer-Reviewed Original ResearchConceptsCognitive domainsInhibitory controlGeneral cognitive abilitySpecific cognitive domainsInhibitory behavioral controlC-reactive proteinPsychotic disordersPsychosis spectrum disordersCognitive abilitiesPeripheral inflammationInflammation factorsSpectrum disorderSensorimotor functionSensorimotor tasksNeurobehavioral domainsGreater deficitsSubgroup of individualsBehavioral controlPsychosis subgroupsCognitive impairmentPreliminary evidenceHigher inflammation scoresNeurobehavioral batteryBrain anatomyBehavioral monitoring
2018
F254. Social Processing Subtyping and Functional Neural Architecture Across Autism Spectrum Disorder, Schizophrenia and Non-Clinical Sample
Assaf M, Corbera S, Rabany L, Brocke S, Pitman B, Johannesen J, Bell M, Calhoun V, Wexler B, Pearlson G. F254. Social Processing Subtyping and Functional Neural Architecture Across Autism Spectrum Disorder, Schizophrenia and Non-Clinical Sample. Biological Psychiatry 2018, 83: s337-s338. DOI: 10.1016/j.biopsych.2018.02.868.Peer-Reviewed Original Research