2024
Maternal Serotonin Levels and Neurodevelopmental Severity in Autistic Children: A Partial Replication and Extension
Jutla A, Shuffrey L, Guter S, Anderson G, O'Reilly K, Montgomery A, Sutcliffe J, Cook E, Veenstra-VanderWeele J. Maternal Serotonin Levels and Neurodevelopmental Severity in Autistic Children: A Partial Replication and Extension. JAACAP Open 2024 DOI: 10.1016/j.jaacop.2024.09.005.Peer-Reviewed Original ResearchLatent profile analysisSevere profileAdaptive functioningAssociated with social impairmentAutistic childrenAutism symptom severityAutism spectrum disorderNonverbal IQSerotonin systemSocial impairmentAutistic traitsRepetitive behaviorsSerotonin levelsSymptom severityHigh-severity groupSpectrum disorderPartial replicationGroup levelSevere groupExploratory modelProfile analysisChildrenStratified participantsSeveritySerotoninLong COVID-19 and Peripheral Serotonin: A Commentary and Reconsideration
Anderson G, Cook E, Blakely R, Sutcliffe J, Veenstra-VanderWeele J. Long COVID-19 and Peripheral Serotonin: A Commentary and Reconsideration. Journal Of Inflammation Research 2024, 17: 2169-2172. PMID: 38628604, PMCID: PMC11019386, DOI: 10.2147/jir.s456000.Peer-Reviewed Original ResearchPlatelet serotoninSerotonin valuesTrials of SSRIsSerotonin reuptake inhibitorsPlatelet serotonin transportersSerotonin reductionSSRI administrationSSRI treatmentReuptake inhibitorsSerotonin transporterMemory impairmentSerotonin levelsSSRIsSerotoninDepletion of plateletsPlasma serotoninPeripheral serotoninSequelae of COVID-19Viremia patientsCardiovascular sequelaeCirculating serotoninHyperaggregable stateTreatment of COVID-19Clinical trialsLong COVID
1993
Cerebrospinal fluid levels of homovanillic acid and 5-hydroxyindoleacetic acid in autism
Narayan M, Srinath S, Anderson G, Meundi DB. Cerebrospinal fluid levels of homovanillic acid and 5-hydroxyindoleacetic acid in autism. Biological Psychiatry 1993, 33: 630-635. PMID: 7687150, DOI: 10.1016/0006-3223(93)90102-j.Peer-Reviewed Original ResearchConceptsCSF homovanillic acidHomovanillic acidCerebrospinal fluid concentrationsCerebrospinal fluid levelsDopamine turnoverDopamine metabolitesCentral serotoninControl groupFluid levelsFluid concentrationsMarked alterationsGroup differencesAutistic disorderAutistic subjectsSerotoninChildrenAutistic childrenAlterationsGroupAutismPrevious studies
1992
Platelet dense granule release reaction monitored by high-performance liquid chromatography-fluorometric determination of endogenous serotonin
Anderson G, Hall L, Yang J, Cohen D. Platelet dense granule release reaction monitored by high-performance liquid chromatography-fluorometric determination of endogenous serotonin. Analytical Biochemistry 1992, 206: 64-67. PMID: 1456443, DOI: 10.1016/s0003-2697(05)80011-9.Peer-Reviewed Original Research
1990
Serotonin in human lumbar cerebrospinal fluid: A reassessment
Anderson G, Mefford I, Tolliver T, Riddle M, Ocame D, Leckman J, Cohen D. Serotonin in human lumbar cerebrospinal fluid: A reassessment. Life Sciences 1990, 46: 247-255. PMID: 2304369, DOI: 10.1016/0024-3205(90)90030-u.Peer-Reviewed Original ResearchConceptsLumbar cerebrospinal fluidCerebrospinal fluidHuman lumbar cerebrospinal fluidCentral serotonergic functionHigh-performance liquid chromatographySerotonergic functionClinical utilityPg/Normal humansMean levelsPrevious reportsPerformance liquid chromatographyMean concentrationLiquid chromatographySerotonin
1989
Whole blood serotonin and tryptophan in autism: Temporal stability and the effects of medication
Minderaa R, Anderson G, Volkmar F, Harcherick D, Akkerhuis G, Cohen D. Whole blood serotonin and tryptophan in autism: Temporal stability and the effects of medication. Journal Of Autism And Developmental Disorders 1989, 19: 129-136. PMID: 2708296, DOI: 10.1007/bf02212724.Peer-Reviewed Original ResearchConceptsWhole blood serotoninPlatelet countMedicated groupBlood serotoninSex-matched normal controlsSignificant intraclass correlation coefficientsEffects of medicationWhole blood concentrationsAutistic groupIntraclass correlation coefficientMean percentage differenceBlood concentrationsNormal controlsNormal subjectsWhole bloodTRP valuesSerotoninTryptophan valuesYear periodGroupCountPercentage differenceMedicationsBlood
1987
WHOLE BLOOD SEROTONIN IN AUTISTIC AND NORMAL SUBJECTS
Anderson G, Freedman D, Cohen D, Volkmar F, Hoder E, McPhedran P, Minderaa R, Hansen C, Young J. WHOLE BLOOD SEROTONIN IN AUTISTIC AND NORMAL SUBJECTS. Journal Of Child Psychology And Psychiatry 1987, 28: 885-900. PMID: 3436995, DOI: 10.1111/j.1469-7610.1987.tb00677.x.Peer-Reviewed Original ResearchConceptsWhole blood serotoninSerotonin levelsBlood serotoninNormal subjectsWhole blood serotonin concentrationAutistic subjectsBlood serotonin concentrationsBlood tryptophan levelsLow serotonin levelsHyperserotonemia of autismPlatelet countSerotonin concentrationsNormal groupTryptophan levelsSerotoninAutistic groupSubjectsPossible causesAnticonvulsantsNeurolepticsGroupLevelsHyperserotonemiaUrinary 5-hydroxyindoleacetic acid and whole blood serotonin and tryptophan in autistic and normal subjects
Minderaa R, Anderson G, Volkmar F, Akkerhuis G, Cohen D. Urinary 5-hydroxyindoleacetic acid and whole blood serotonin and tryptophan in autistic and normal subjects. Biological Psychiatry 1987, 22: 933-940. PMID: 2440483, DOI: 10.1016/0006-3223(87)90002-3.Peer-Reviewed Original Research
1985
Cerebrospinal fluid (CSF) and brain monoamine metabolites in the developing rat pup
Shaywitz B, Anderson G, Cohen D. Cerebrospinal fluid (CSF) and brain monoamine metabolites in the developing rat pup. Brain Research 1985, 17: 225-232. DOI: 10.1016/0165-3806(85)90146-4.Peer-Reviewed Original ResearchEffect of a Meal on Human Whole Blood Serotonin
Anderson G, Feibel F, Wetlaufer L, Schlicht K, Ort S, Cohen D. Effect of a Meal on Human Whole Blood Serotonin. Gastroenterology 1985, 88: 86-89. PMID: 2578039, DOI: 10.1016/s0016-5085(85)80137-2.Peer-Reviewed Original ResearchConceptsWhole blood serotoninMicrograms/hBlood serotoninGastrointestinal hormonesUrinary excretionSerotonin levelsBlood samplesUrine specimensBaseline levelsSerotoninSecond hourWhole bloodHuman subjectsSpecific high-performance liquid chromatographic methodMealMinSubjectsUrinaryLevelsExcretionBloodHormone
1984
Whole blood serotonin and tryptophan levels in Tourette's disorder: Effects of acute and chronic clonidine treatment
Leckman J, Anderson G, Cohen D, Ort S, Harcherik D, Hoder E, Shaywitz B. Whole blood serotonin and tryptophan levels in Tourette's disorder: Effects of acute and chronic clonidine treatment. Life Sciences 1984, 35: 2497-2503. PMID: 6595491, DOI: 10.1016/0024-3205(84)90435-1.Peer-Reviewed Original ResearchConceptsChronic clonidine treatmentClonidine treatmentTourette's disorder patientsWhole blood serotoninDisorder patientsTourette's disorderBlood serotoninTryptophan levelsMean differenceChronic treatmentAcute doseNormal controlsMean increaseClonidinePatientsDisordersMode of actionTreatmentSignificant differencesSerotoninBaseline conditionsLevelsDifferencesDose
1982
Clinical neurochemistry of autism and associated disorders
Young J, Kavanagh M, Anderson G, Shaywitz B, Cohen D. Clinical neurochemistry of autism and associated disorders. Journal Of Autism And Developmental Disorders 1982, 12: 147-165. PMID: 6184361, DOI: 10.1007/bf01531305.Peer-Reviewed Original ResearchConceptsNorepinephrine metabolismNeurochemical methodsClinical neurochemistryClinical studiesNeurochemical studiesBehavioral deficitsBiochemical dysfunctionBrain functionAutistic syndromeInfantile autismLow levelsNew studiesAutismDysfunctionSerotoninSyndromeAutistic individualsSymptomsNeurochemistryBrainMajor obstacle
1981
Determination of indoles and catechols in rat brain and pineal using liquid chromatography with fluorometric and amperometric detection
Anderson G, Young J, Batter D, Young S, Cohen D, Shaywitz B. Determination of indoles and catechols in rat brain and pineal using liquid chromatography with fluorometric and amperometric detection. Journal Of Chromatography 1981, 223: 315-320. PMID: 7251785, DOI: 10.1016/s0378-4347(00)80103-6.Peer-Reviewed Original Research