2015
Striatal‐enriched protein tyrosine phosphatase regulates the PTPα/Fyn signaling pathway
Xu J, Kurup P, Foscue E, Lombroso PJ. Striatal‐enriched protein tyrosine phosphatase regulates the PTPα/Fyn signaling pathway. Journal Of Neurochemistry 2015, 134: 629-641. PMID: 25951993, PMCID: PMC4516628, DOI: 10.1111/jnc.13160.Peer-Reviewed Original ResearchConceptsProtein tyrosine phosphataseProtein kinase ARegulation of FynTyrosine phosphataseReceptor-type protein tyrosine phosphatase alphaProtein tyrosine phosphatase alphaStriatal-enriched protein tyrosine phosphataseRegulatory tyrosine residuesActivation of FynTyrosine kinase FynRegulatory tyrosineProtein tyrosinePTPαKinase FynSynaptic membranesKinase ATyrosine residuesFyn activityFynNovel substratePrimary neuronal culturesSTEP61Synergistic regulationMolecular techniquesNovel mechanism
2012
Characterization of a semi-rapid method for assessing delay discounting in rodents
Foscue E, Wood K, Schramm-Sapyta N. Characterization of a semi-rapid method for assessing delay discounting in rodents. Pharmacology Biochemistry And Behavior 2012, 101: 187-192. PMID: 22266769, PMCID: PMC3288622, DOI: 10.1016/j.pbb.2012.01.006.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsChoice BehaviorCocaineImpulsive BehaviorMaleRatsRats, Sprague-DawleyRewardTime FactorsConceptsImportant disease processesChronic treatmentRodent modelsPsychiatric disordersDisease processDaily sessionsStable response patternsDrug addictionUnderlying mechanismSession learningOperant responseFuture studiesResponse patternsStable baselineExtended trainingCompulsive gamblingSubsequent daily sessionsObesityBaselineMonthsCocaine
2010
Aversive Effects of Ethanol in Adolescent Versus Adult Rats: Potential Causes and Implication for Future Drinking
Schramm‐Sapyta N, DiFeliceantonio AG, Foscue E, Glowacz S, Haseeb N, Wang N, Zhou C, Kuhn CM. Aversive Effects of Ethanol in Adolescent Versus Adult Rats: Potential Causes and Implication for Future Drinking. Alcohol Clinical And Experimental Research 2010, 34: 2061-2069. PMID: 20860614, PMCID: PMC2988872, DOI: 10.1111/j.1530-0277.2010.01302.x.Peer-Reviewed Original ResearchConceptsAversive effectsAdolescents Versus AdultsProblem drinking behaviorDrug seeking behaviorBlood ethanol concentrationTaste aversionFuture drinkingAdolescent ratsAge differencesDrugs of abuseEthanol CTADrug takingDrinking behaviorAdolescentsPhysiologic effectsAdult ratsTeenage yearsIndividual variationRodent studiesAbuseAdultsSeeking behaviourDrug intakeEpidemiological evidenceSedative effects