Featured Publications
Central vein sign: A diagnostic biomarker in multiple sclerosis (CAVS-MS) study protocol for a prospective multicenter trial
Ontaneda D, Sati P, Raza P, Kilbane M, Gombos E, Alvarez E, Azevedo C, Calabresi P, Cohen JA, Freeman L, Henry RG, Longbrake EE, Mitra N, Illenberger N, Schindler M, Moreno-Dominguez D, Ramos M, Mowry E, Oh J, Rodrigues P, Chahin S, Kaisey M, Waubant E, Cutter G, Shinohara R, Reich DS, Solomon A, Sicotte NL, Cooperative N. Central vein sign: A diagnostic biomarker in multiple sclerosis (CAVS-MS) study protocol for a prospective multicenter trial. NeuroImage Clinical 2021, 32: 102834. PMID: 34592690, PMCID: PMC8482479, DOI: 10.1016/j.nicl.2021.102834.Peer-Reviewed Original ResearchConceptsCentral vein signDiagnosis of MSMultiple sclerosisDiagnostic biomarkersMcDonald criteriaVein signProspective multicenter trialCross-sectional studyNumerous cross-sectional studiesNorth American ImagingNeuroradiologist reviewMulticenter trialAtypical presentationMulticenter studyTypical presentationSectional studyStudy protocolClinical careMS lesionsCentral readersEcho-planar MRIDiagnostic criteriaMS misdiagnosisMRI biomarkersMajor cause
2016
Quantitative visual tests after poorly recovered optic neuritis due to multiple sclerosis
Longbrake EE, Lancia S, Tutlam N, Trinkaus K, Naismith RT. Quantitative visual tests after poorly recovered optic neuritis due to multiple sclerosis. Multiple Sclerosis And Related Disorders 2016, 10: 198-203. PMID: 27919490, PMCID: PMC5392253, DOI: 10.1016/j.msard.2016.10.009.Peer-Reviewed Original ResearchConceptsRetinal nerve fiber layerOptic neuritisVisual dysfunctionMS patientsContrast chartsVisual fieldVFQ-25 scoresPelli-Robson contrast sensitivity chartNerve fiber layerSevere visual dysfunctionSnellen eye chartLow contrast chartsCross-sectional studyContrast sensitivity testQuality of lifeContrast sensitivity chartLow-contrast testsOptical coherence tomographyMultiple sclerosisVisual acuityElectrophysiologic functionPatientsEye chartPR chartNeuritis