2024
Epidemiology of cardiogenic shock using the Shock Academic Research Consortium (SHARC) consensus definitions
Berg D, Bohula E, Patel S, Alfonso C, Alviar C, Baird-Zars V, Barnett C, Barsness G, Bennett C, Chaudhry S, Fordyce C, Ghafghazi S, Gidwani U, Goldfarb M, Katz J, Menon V, Miller P, Newby L, Papolos A, Park J, Pierce M, Proudfoot A, Sinha S, Sridharan L, Thompson A, van Diepen S, Morrow D. Epidemiology of cardiogenic shock using the Shock Academic Research Consortium (SHARC) consensus definitions. European Heart Journal Acute Cardiovascular Care 2024, 13: 709-714. PMID: 39208447, PMCID: PMC11518926, DOI: 10.1093/ehjacc/zuae098.Peer-Reviewed Original ResearchCardiac intensive care unitSecondary CSConsensus definitionConcomitant cardiac arrestCritical Care Cardiology Trials NetworkRelevant to clinical practiceAcademic Research ConsortiumIn-hospital mortalityResearch ConsortiumCardiogenic shockIntensive care unitMultinational research networksCardiac arrestClinical practiceEvidence of hypoperfusionCare unitTrials NetworkTIMI Study GroupContemporary registryRegistryShock criteriaCS classificationStudy groupEpidemiologyClinical trialsManagement of Post-cardiotomy Shock
Hall E, Papolos A, Miller P, Barnett C, Kenigsberg B. Management of Post-cardiotomy Shock. US Cardiology Review 2024, 18: e11. PMID: 39494414, PMCID: PMC11526484, DOI: 10.15420/usc.2024.16.Peer-Reviewed Original ResearchTemperature Control Parameters Are Important: Earlier Preinduction Is Associated With Improved Outcomes Following Out-of-Hospital Cardiac Arrest
Beekman R, Kim N, Nguyen C, McGinniss G, Deng Y, Kitlen E, Garcia G, Wira C, Khosla A, Johnson J, Miller P, Perman S, Sheth K, Greer D, Gilmore E. Temperature Control Parameters Are Important: Earlier Preinduction Is Associated With Improved Outcomes Following Out-of-Hospital Cardiac Arrest. Annals Of Emergency Medicine 2024, 84: 549-559. PMID: 39033449, DOI: 10.1016/j.annemergmed.2024.06.007.Peer-Reviewed Original ResearchOut-of-hospital cardiac arrestNeurological outcomeDevice cohortCardiac arrestOut-of-hospital cardiac arrest patientsConsecutive out-of-hospital cardiac arrestPreinduction timeInterquartile rangeAssociated with improved outcomesCardiac arrest patientsProportion of patientsMultivariate logistic regression modelInverse probability of treatmentDevice timeInverse probability treatment weightsProbability of treatmentProspective trialsOHCA patientsArrest patientsClinical outcomesLogistic regression modelsCenter studyEarly initiationSecondary outcomesTreatment weightingCan Clinical Scores Predict the Presence of Hypoxic Ischemic Brain Injury on Early Head Computed Tomography After Cardiac Arrest? (P6-2.001)
Nguyen C, Molligoda B, Kim N, Kitlen E, Wira C, Perman S, Khosla A, Miller P, Greer D, Gilmore E, Beekman R. Can Clinical Scores Predict the Presence of Hypoxic Ischemic Brain Injury on Early Head Computed Tomography After Cardiac Arrest? (P6-2.001). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000206255.Peer-Reviewed Original ResearchThe Impact of Socioeconomic Status on Risk for Brain Death Following Out-of-Hospital Cardiac Arrest (P1-4.014)
Fung C, Kitlen E, Nguyen C, Kim N, Wira C, Perman S, Khosla A, Miller P, Greer D, Gilmore E, Beekman R. The Impact of Socioeconomic Status on Risk for Brain Death Following Out-of-Hospital Cardiac Arrest (P1-4.014). Neurology 2024, 102 DOI: 10.1212/wnl.0000000000206574.Peer-Reviewed Original Research
2022
Characteristics, therapies, and outcomes of In-Hospital vs Out-of-Hospital cardiac arrest in patients presenting to cardiac intensive care units: From the critical care Cardiology trials network (CCCTN)
Carnicelli A, Keane R, Brown K, Loriaux D, Kendsersky P, Alviar C, Arps K, Berg D, Bohula E, Burke J, Dixson J, Gerber D, Goldfarb M, Granger C, Guo J, Harrison R, Kontos M, Lawler P, Miller P, Nativi-Nicolau J, Newby L, Racharla L, Roswell R, Shah K, Sinha S, Solomon M, Teuteberg J, Wong G, van Diepen S, Katz J, Morrow D. Characteristics, therapies, and outcomes of In-Hospital vs Out-of-Hospital cardiac arrest in patients presenting to cardiac intensive care units: From the critical care Cardiology trials network (CCCTN). Resuscitation 2022, 183: 109664. PMID: 36521683, PMCID: PMC9899313, DOI: 10.1016/j.resuscitation.2022.12.002.Peer-Reviewed Original ResearchConceptsCardiac intensive care unitCritical Care Cardiology Trials NetworkOutcome of admissionIntensive care unitCardiac arrestCare unitContemporary cardiac intensive care unitsTertiary cardiac intensive care unitsTrials NetworkLower lactateLower crude mortalityRenal replacement therapyMechanical circulatory supportHospital cardiac arrestHospital mortalityIHCA patientsInvasive hemodynamicsCICU admissionIn-HospitalCoronary diseaseCrude mortalityHeart failureOHCA patientsAtrial fibrillationCirculatory supportOxygen Supplementation and Hyperoxia in Critically Ill Cardiac Patients From Pathophysiology to Clinical Practice
Thomas A, van Diepen S, Beekman R, Sinha SS, Brusca SB, Alviar CL, Jentzer J, Bohula EA, Katz JN, Shahu A, Barnett C, Morrow DA, Gilmore EJ, Solomon MA, Miller PE. Oxygen Supplementation and Hyperoxia in Critically Ill Cardiac Patients From Pathophysiology to Clinical Practice. JACC Advances 2022, 1: 100065. PMID: 36238193, PMCID: PMC9555075, DOI: 10.1016/j.jacadv.2022.100065.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsOxygen supplementationIntensive care unit cliniciansHarmful hemodynamic effectsAdverse clinical outcomesIll cardiac patientsManagement of patientsAcute cardiac diseaseAcute myocardial infarctionDirect cellular toxicityCoronary vasoconstrictionPulmonary hypertensionRespiratory failureHemodynamic effectsHeart failureOxygen therapyClinical outcomesSupplemental oxygenAvailable trialsCardiac arrestMyocardial infarctionCardiac patientsCardiac diseaseClinical practiceCardiovascular systemHyperoxiaStaffing models in the cardiac intensive care unit
Quien M, Thomas A, Ludmir J, Miller PE. Staffing models in the cardiac intensive care unit. Current Opinion In Critical Care 2022, 28: 453-459. PMID: 35757936, DOI: 10.1097/mcc.0000000000000958.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsCardiac intensive care unitIntensive care unitCare unitContemporary cardiac intensive care unitsModern cardiac intensive care unitMechanical circulatory supportSick patient populationFuture multicenter studiesStaffing modelsPreponderance of dataShock teamRespiratory failureIll patientsCirculatory supportMulticenter studyCardiac arrestPatient populationCardiac intensivistsIll populationMortalityRecent evidenceIntensivistsPatientsRecent dataPopulation
2021
Transition From an Open to Closed Staffing Model in the Cardiac Intensive Care Unit Improves Clinical Outcomes
Miller PE, Chouairi F, Thomas A, Kunitomo Y, Aslam F, Canavan ME, Murphy C, Daggula K, Metkus T, Vallabhajosyula S, Carnicelli A, Katz JN, Desai NR, Ahmad T, Velazquez EJ, Brennan J. Transition From an Open to Closed Staffing Model in the Cardiac Intensive Care Unit Improves Clinical Outcomes. Journal Of The American Heart Association 2021, 10: e018182. PMID: 33412899, PMCID: PMC7955420, DOI: 10.1161/jaha.120.018182.Peer-Reviewed Original ResearchConceptsCardiac intensive care unitIntensive care unitHospital mortalityCare unitCICU mortalityClinical outcomesModern cardiac intensive care unitSurgical intensive care unitTotal hospital chargesSeverity of illnessMultivariable logistic regressionCICU lengthMultivariable adjustmentRespiratory insufficiencyPrimary outcomeUnique admissionsHospital chargesCardiac arrestSubgroup analysisImproved outcomesMortalityLogistic regressionAdmissionClosed unitStaffing models
2018
Positive Pressure Ventilation in the Cardiac Intensive Care Unit
Alviar CL, Miller PE, McAreavey D, Katz JN, Lee B, Moriyama B, Soble J, van Diepen S, Solomon MA, Morrow DA, Group A. Positive Pressure Ventilation in the Cardiac Intensive Care Unit. Journal Of The American College Of Cardiology 2018, 72: 1532-1553. PMID: 30236315, PMCID: PMC11032173, DOI: 10.1016/j.jacc.2018.06.074.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsContemporary cardiac intensive care unitsPositive pressure ventilationInvasive positive pressure ventilationCardiac intensive care unitIntensive care unitCare unitPressure ventilationNoninvasive positive pressure ventilationMechanical positive pressure ventilationCardiogenic pulmonary edemaProportion of patientsManagement of patientsRisk of complicationsMechanical circulatory supportComplex patient populationRight ventricular physiologyCICU mortalityCardiogenic shockRespiratory failurePulmonary edemaCirculatory supportCardiac arrestPatient populationVentricular physiologyMedical complexity