2024
Outcomes for Mechanically Ventilated Patients With Acute Myocardial Infarction Admitted to Medical vs Cardiac Intensive Care Units
Shahu A, Namburar S, Banna S, Harris A, Schenck C, Trejo-Paredes C, Thomas A, Ali T, Carnicelli A, Barnett C, Solomon M, Miller P. Outcomes for Mechanically Ventilated Patients With Acute Myocardial Infarction Admitted to Medical vs Cardiac Intensive Care Units. JACC Advances 2024, 3: 101199. PMID: 39238851, PMCID: PMC11375252, DOI: 10.1016/j.jacadv.2024.101199.Peer-Reviewed Original ResearchAcute myocardial infarctionAssociated with lower in-hospital mortalityIn-hospital mortalityLower in-hospital mortalityIntensive care unitMedical ICUPrimary diagnosis of acute myocardial infarctionMultivariable adjustmentCICU admissionInvasive mechanical ventilationVizient Clinical Data BaseBackground Acute myocardial infarctionDiagnosis of acute myocardial infarctionMultivariate logistic regressionMedical intensive care unitClinical outcomesMechanical ventilationCardiogenic shockClinical Data BaseMyocardial infarctionHospital sizeTriage of critically ill patientsMedian ventilator daysTeaching hospitalLogistic regressionArterial hyperoxia and mortality in the cardiac intensive care unit
Jentzer J, van Diepen S, Alviar C, Miller P, Metkus T, Geller B, Kashani K. Arterial hyperoxia and mortality in the cardiac intensive care unit. Current Problems In Cardiology 2024, 49: 102738. PMID: 39025170, DOI: 10.1016/j.cpcardiol.2024.102738.Peer-Reviewed Original ResearchCardiac intensive care unitIn-hospital mortalityIntensive care unitEvaluate predictors of in-hospital mortalityArterial hyperoxiaPaO2 >Mayo Clinic CICU patientsAssociated with increased in-hospital mortalityCare unitPredictors of in-hospital mortalityAssociated with higher in-hospital mortalityAssociated with adverse outcomesTime of CICU admissionAdmission PaO2Higher in-hospital mortalityCritically ill populationArterial partial pressure of oxygenPositive-pressure ventilationJ-shaped associationExposure to hyperoxiaCICU patientsArterial partial pressureCICU admissionEvaluate predictorsMedian PaO2
2023
Prognostic significance of haemodynamic parameters in patients with cardiogenic shock
Berg D, Kaur G, Bohula E, Baird-Zars V, Alviar C, Barnett C, Barsness G, Burke J, Chaudhry S, Chonde M, Cooper H, Daniels L, Dodson M, Gerber D, Ghafghazi S, Gidwani U, Goldfarb M, Guo J, Hillerson D, Kenigsberg B, Kochar A, Kontos M, Kwon Y, Lopes M, Loriaux D, Miller P, O’Brien C, Papolos A, Patel S, Pisani B, Potter B, Prasad R, Roswell R, Shah K, Sinha S, Smith T, Solomon M, Teuteberg J, Thompson A, Zakaria S, Katz J, van Diepen S, Morrow D. Prognostic significance of haemodynamic parameters in patients with cardiogenic shock. European Heart Journal Acute Cardiovascular Care 2023, 12: 651-660. PMID: 37640029, PMCID: PMC10599641, DOI: 10.1093/ehjacc/zuad095.Peer-Reviewed Original ResearchConceptsCardiac intensive care unitInvasive haemodynamic assessmentRight atrial pressureCardiogenic shockHaemodynamic parametersHaemodynamic assessmentCICU admissionSerum lactateCritical Care Cardiology Trials NetworkLower pulmonary artery pulsatility indexPulmonary capillary wedge pressure ratioLow systemic vascular resistancePulmonary artery pulsatility indexLower systolic blood pressureTemporary mechanical circulatory supportMedian cardiac indexTIMI Study GroupVasoactive-inotropic scoreArtery pulsatility indexEnd-organ dysfunctionRight ventricular dysfunctionSystemic vascular resistancePulmonary artery catheterSystolic blood pressureManagement of patientsPulmonary Artery Catheter Use and Mortality in the Cardiac Intensive Care Unit
Kadosh B, Berg D, Bohula E, Park J, Baird-Zars V, Alviar C, Alzate J, Barnett C, Barsness G, Burke J, Chaudhry S, Daniels L, DeFilippis A, Delicce A, Fordyce C, Ghafghazi S, Gidwani U, Goldfarb M, Katz J, Keeley E, Kenigsberg B, Kontos M, Lawler P, Leibner E, Menon V, Metkus T, Miller P, O'Brien C, Papolos A, Prasad R, Shah K, Sinha S, Snell R, So D, Solomon M, Ternus B, Teuteberg J, Toole J, van Diepen S, Morrow D, Roswell R. Pulmonary Artery Catheter Use and Mortality in the Cardiac Intensive Care Unit. JACC Heart Failure 2023, 11: 903-914. PMID: 37318422, PMCID: PMC10527413, DOI: 10.1016/j.jchf.2023.04.007.Peer-Reviewed Original ResearchConceptsCardiac intensive care unitPulmonary artery catheterUse of PACHospital mortalityCare unitPAC useCardiac patientsCritical Care Cardiology Trials NetworkPulmonary artery catheter usePatient-level factorsIll cardiac patientsIntensive care unitMechanical circulatory supportCardiac critical careAppropriate useCardiogenic etiologyAdmission diagnosisShock patientsCatheter useArtery catheterCICU admissionHeart failureRandomized trialsCirculatory supportCritical care
2022
Characteristics, therapies, and outcomes of In-Hospital vs Out-of-Hospital cardiac arrest in patients presenting to cardiac intensive care units: From the critical care Cardiology trials network (CCCTN)
Carnicelli A, Keane R, Brown K, Loriaux D, Kendsersky P, Alviar C, Arps K, Berg D, Bohula E, Burke J, Dixson J, Gerber D, Goldfarb M, Granger C, Guo J, Harrison R, Kontos M, Lawler P, Miller P, Nativi-Nicolau J, Newby L, Racharla L, Roswell R, Shah K, Sinha S, Solomon M, Teuteberg J, Wong G, van Diepen S, Katz J, Morrow D. Characteristics, therapies, and outcomes of In-Hospital vs Out-of-Hospital cardiac arrest in patients presenting to cardiac intensive care units: From the critical care Cardiology trials network (CCCTN). Resuscitation 2022, 183: 109664. PMID: 36521683, PMCID: PMC9899313, DOI: 10.1016/j.resuscitation.2022.12.002.Peer-Reviewed Original ResearchConceptsCardiac intensive care unitCritical Care Cardiology Trials NetworkOutcome of admissionIntensive care unitCardiac arrestCare unitContemporary cardiac intensive care unitsTertiary cardiac intensive care unitsTrials NetworkLower lactateLower crude mortalityRenal replacement therapyMechanical circulatory supportHospital cardiac arrestHospital mortalityIHCA patientsInvasive hemodynamicsCICU admissionIn-HospitalCoronary diseaseCrude mortalityHeart failureOHCA patientsAtrial fibrillationCirculatory supportPatients With Acute Coronary Syndromes Admitted to Contemporary Cardiac Intensive Care Units: Insights From the CCCTN Registry
Fagundes A, Berg DD, Park JG, Baird-Zars VM, Newby LK, Barsness GW, Miller PE, van Diepen S, Katz JN, Phreaner N, Roswell RO, Menon V, Daniels LB, Morrow DA, Bohula EA, Investigators F. Patients With Acute Coronary Syndromes Admitted to Contemporary Cardiac Intensive Care Units: Insights From the CCCTN Registry. Circulation Cardiovascular Quality And Outcomes 2022, 15: e008652. PMID: 35862019, DOI: 10.1161/circoutcomes.121.008652.Peer-Reviewed Original ResearchConceptsCardiac intensive care unitAcute coronary syndromeContemporary cardiac intensive care unitsIntensive care unitCICU admissionAdmission indicationsCICU mortalityCoronary syndromeCare unitPrimary diagnosisIntensive care unit therapyEpidemiology of patientsNon-ACS diagnosisLow-risk patientsTime of admissionCICU lengthAcute severityVasoactive therapyPatient characteristicsRespiratory insufficiencyRisk patientsCommon indicationRoutine admissionACS admissionsProspective study
2021
The association between cardiac intensive care unit mechanical ventilation volumes and in-hospital mortality
Nandiwada S, Islam S, Jentzer JC, Miller PE, Fordyce CB, Lawler P, Alviar CL, Sun LY, Dover DC, Lopes RD, Kaul P, van Diepen S. The association between cardiac intensive care unit mechanical ventilation volumes and in-hospital mortality. European Heart Journal Acute Cardiovascular Care 2021, 10: 797-805. PMID: 34318875, PMCID: PMC9067446, DOI: 10.1093/ehjacc/zuab055.Peer-Reviewed Original ResearchConceptsCardiac intensive care unitMechanical ventilationHospital mortalityRespiratory failureCICU LOSNon-invasive mechanical ventilationNational population-based dataInvasive mechanical ventilationVolume-mortality relationshipProlonged mechanical ventilationProportion of patientsHigh-volume hospitalsPercutaneous coronary interventionLow-volume centersHigh-volume centersIntensive care unitPopulation-based dataOutcomes of interestCICU lengthCICU admissionCoronary interventionSurgical ICUCare unitVolume centersLower incidence