2024
Arterial hyperoxia and mortality in the cardiac intensive care unit
Jentzer J, van Diepen S, Alviar C, Miller P, Metkus T, Geller B, Kashani K. Arterial hyperoxia and mortality in the cardiac intensive care unit. Current Problems In Cardiology 2024, 49: 102738. PMID: 39025170, DOI: 10.1016/j.cpcardiol.2024.102738.Peer-Reviewed Original ResearchCardiac intensive care unitIn-hospital mortalityIntensive care unitEvaluate predictors of in-hospital mortalityArterial hyperoxiaPaO2 >Mayo Clinic CICU patientsAssociated with increased in-hospital mortalityCare unitPredictors of in-hospital mortalityAssociated with higher in-hospital mortalityAssociated with adverse outcomesTime of CICU admissionAdmission PaO2Higher in-hospital mortalityCritically ill populationArterial partial pressure of oxygenPositive-pressure ventilationJ-shaped associationExposure to hyperoxiaCICU patientsArterial partial pressureCICU admissionEvaluate predictorsMedian PaO2
2023
Exposure to Arterial Hyperoxia During Extracorporeal Membrane Oxygenator Support and Mortality in Patients With Cardiogenic Shock
Jentzer J, Miller P, Alviar C, Yalamuri S, Bohman J, Tonna J. Exposure to Arterial Hyperoxia During Extracorporeal Membrane Oxygenator Support and Mortality in Patients With Cardiogenic Shock. Circulation Heart Failure 2023, 16: e010328. PMID: 36871240, PMCID: PMC10121893, DOI: 10.1161/circheartfailure.122.010328.Peer-Reviewed Original ResearchConceptsExtracorporeal membrane oxygenator supportMembrane oxygenator supportHospital mortalityCardiogenic shockVenoarterial ECMOSevere hyperoxiaMild hyperoxiaHigher PaO2Extracorporeal Life Support Organization registryHigher arterial partial pressureHours of ECMOVenoarterial ECMO supportMultivariable logistic regressionArterial partial pressureClinical trial dataAcid-base statusArterial hyperoxiaExtracorporeal CPRRegistry patientsECMO supportAirway pressureNormal PaO2Ventilatory statusClinical variablesCS patients