Brain-phenotype predictions of language and executive function can survive across diverse real-world data: Dataset shifts in developmental populations
Adkinson B, Rosenblatt M, Dadashkarimi J, Tejavibulya L, Jiang R, Noble S, Scheinost D. Brain-phenotype predictions of language and executive function can survive across diverse real-world data: Dataset shifts in developmental populations. Developmental Cognitive Neuroscience 2024, 70: 101464. PMID: 39447452, DOI: 10.1016/j.dcn.2024.101464.Peer-Reviewed Original ResearchBrain-phenotype associationsConnectome-based predictive modelingBrain-behavior associationsPrediction of languagePhiladelphia Neurodevelopmental CohortHealthy Brain NetworkClinical symptom burdenFMRI taskHuman Connectome ProjectExecutive functionBehavioral measuresDevelopmental populationsNeurodevelopmental CohortBrain networksDevelopmental sampleConnectome ProjectResearch settingsGeneralizabilitySymptom burdenExternal validationFMRIClinical settingAssociationEthnic minority representationTaskPower and reproducibility in the external validation of brain-phenotype predictions
Rosenblatt M, Tejavibulya L, Sun H, Camp C, Khaitova M, Adkinson B, Jiang R, Westwater M, Noble S, Scheinost D. Power and reproducibility in the external validation of brain-phenotype predictions. Nature Human Behaviour 2024, 8: 2018-2033. PMID: 39085406, DOI: 10.1038/s41562-024-01931-7.Peer-Reviewed Original ResearchHuman Connectome ProjectAdolescent Brain Cognitive Development StudyConnectome ProjectCognitive Development StudyPhiladelphia Neurodevelopmental CohortHealthy Brain NetworkStructural connectivity dataMatrix reasoningWorking memoryAnxiety/depression symptomsAttention problemsNeurodevelopmental CohortBrain networksBrain-phenotype associationsEffect sizeConnectivity dataExternal validationRelated processesValidation studySample sizeBrain ProjectDevelopment studiesTraining sample sizeGeneralizability of modelsExternal samples