2024
Guidelines for Neuroprognostication in Critically Ill Adults with Moderate–Severe Traumatic Brain Injury
Muehlschlegel S, Rajajee V, Wartenberg K, Alexander S, Busl K, Creutzfeldt C, Fontaine G, Hocker S, Hwang D, Kim K, Madzar D, Mahanes D, Mainali S, Meixensberger J, Sakowitz O, Varelas P, Weimar C, Westermaier T. Guidelines for Neuroprognostication in Critically Ill Adults with Moderate–Severe Traumatic Brain Injury. Neurocritical Care 2024, 40: 448-476. PMID: 38366277, PMCID: PMC10959796, DOI: 10.1007/s12028-023-01902-2.Peer-Reviewed Original ResearchTraumatic brain injuryBrain injuryFunctional outcomesSurrogate decision-makersSurrogates of patientsSystematic narrative reviewIMPACT lab modelQuality of evidenceClinical variablesDesirability of outcomesClinically relevant predictorsCritically ill adultsRecommendations AssessmentComfort measuresIn-hospital mortalityConclusionsThese guidelinesMsTBIEligibility criteriaPoor outcomeIll adultsPatient triagePractice recommendationsIndividual predictorsInternational Mission for PrognosisNarrative review
2023
Guidelines for Neuroprognostication in Critically Ill Adults with Intracerebral Hemorrhage
Hwang D, Kim K, Muehlschlegel S, Wartenberg K, Rajajee V, Alexander S, Busl K, Creutzfeldt C, Fontaine G, Hocker S, Madzar D, Mahanes D, Mainali S, Sakowitz O, Varelas P, Weimar C, Westermaier T, Meixensberger J. Guidelines for Neuroprognostication in Critically Ill Adults with Intracerebral Hemorrhage. Neurocritical Care 2023, 40: 395-414. PMID: 37923968, PMCID: PMC10959839, DOI: 10.1007/s12028-023-01854-7.Peer-Reviewed Original ResearchClinical grading scaleClinical variablesGrading scaleRecommendations AssessmentPoor outcomeIntensive care unit admissionCandidate clinical variablesCritically Ill AdultsIndividual clinical variablesMajor clinical predictorsCare unit admissionCounseling of patientsBest practice statementsJudgment of prognosisNarrative systematic reviewConclusionsThese guidelinesUnit admissionNeurological recoveryClinical predictorsIll adultsCounseling patientsIntracerebral hemorrhageFunctional outcomeConsensus statementNeuroprognostication
2020
The impact of delirium on withdrawal of life-sustaining treatment after intracerebral hemorrhage.
Reznik ME, Moody S, Murray K, Costa S, Grory BM, Madsen TE, Mahta A, Wendell LC, Thompson BB, Rao SS, Stretz C, Sheth KN, Hwang DY, Zahuranec DB, Schrag M, Daiello LA, Asaad WF, Jones RN, Furie KL. The impact of delirium on withdrawal of life-sustaining treatment after intracerebral hemorrhage. Neurology 2020, 95: e2727-e2735. PMID: 32913011, PMCID: PMC7734724, DOI: 10.1212/wnl.0000000000010738.Peer-Reviewed Original ResearchConceptsImpact of deliriumIntracerebral hemorrhageLife-sustaining treatmentScore-based modelSingle-center cohort studyCox regression modelCharacteristic curve analysisDSM-5 criteriaHospital daysCohort studyConsecutive patientsMedian timeDelirium groupPoor outcomeDeliriumWLSTPatientsLogistic regressionCurve analysisHemorrhage