Role of Neurocellular Endoplasmic Reticulum Stress Response in Alzheimer’s Disease and Related Dementias Risk
Aceves M, Granados J, Leandro A, Peralta J, Glahn D, Williams-Blangero S, Curran J, Blangero J, Kumar S. Role of Neurocellular Endoplasmic Reticulum Stress Response in Alzheimer’s Disease and Related Dementias Risk. Genes 2024, 15: 569. PMID: 38790197, PMCID: PMC11121587, DOI: 10.3390/genes15050569.Peer-Reviewed Original ResearchTranscriptional response to ER stressProtein kinase RNA-like ER kinaseActivating transcription factor 6Inositol-requiring enzyme-1ER stress responseUnfolded protein responseElevated endoplasmic reticulumAlzheimer's diseaseResponse to ER stressSarco/endoplasmic reticulum Ca2+-ATPaseNeural stem cellsRNA-like ER kinaseStress responseAnalysis of DE genesG1/S phase cell cycle arrestEndoplasmic reticulum stress responseInduced G1/S-phase cell cycle arrestPostmortem AD brainsGene network analysisTranscription factor 6E2F transcription factor 1Animal models of ADCell cycle arrestModel of ADBinding protein 1