2024
Clinical physiology: the crucial role of MRI in evaluation of peripheral artery disease
Elsaid N, Peters D, Galiana G, Sinusas A. Clinical physiology: the crucial role of MRI in evaluation of peripheral artery disease. AJP Heart And Circulatory Physiology 2024, 326: h1304-h1323. PMID: 38517227, PMCID: PMC11381027, DOI: 10.1152/ajpheart.00533.2023.Peer-Reviewed Original ResearchPeripheral arterial diseaseMagnetic resonance imagingArtery diseaseClinical applicationEvaluation of peripheral arterial diseaseTranslation to clinical researchPre-clinical modelsMedial vascular calcificationDiagnosis of peripheral arterial diseaseExcellent soft tissue contrastPathophysiology of peripheral arterial diseaseAssessment of peripheral arterial diseaseNoninvasive imaging toolMR imaging technologyMR imaging techniquesSoft tissue contrastMultiplanar imaging capabilityAutonomic dysfunctionMicrovascular dysfunctionRisk stratificationPeripheral neuropathyComprehensive physiological assessmentTreatment outcomesVascular calcificationTherapy planningKiosk 5R-TA-01 Left Atrial Evaluation in Immune Check Point Inhibitor Myocarditis Using Cardiac Magnetic Resonance Imaging and Correlations with Cardiovascular Outcomes
Jeyashanmugaraja G, Kwan J, Shah N, Lamy J, Khattab M, Chehayeb R, Guajardo A, Lin D, Christofides A, Alkhatib D, Martinez C, Im Y, Salem J, Redheuil A, Peters D, Baldassarre L. Kiosk 5R-TA-01 Left Atrial Evaluation in Immune Check Point Inhibitor Myocarditis Using Cardiac Magnetic Resonance Imaging and Correlations with Cardiovascular Outcomes. Journal Of Cardiovascular Magnetic Resonance 2024, 26: 100677. DOI: 10.1016/j.jocmr.2024.100677.Peer-Reviewed Original ResearchCardiac magnetic resonance imagingMagnetic resonance imagingCardiovascular outcomesResonance imaging
2021
57884 Fast strain-encoded cardiac magnetic resonance detects immune checkpoint inhibitor associated cardiotoxicity
Cuomo J, Ragheb E, Feher A, Kwan J, Huber S, Mojibian H, Peters D, Sinusas A, Baldassarre L. 57884 Fast strain-encoded cardiac magnetic resonance detects immune checkpoint inhibitor associated cardiotoxicity. Journal Of Clinical And Translational Science 2021, 5: 141-142. PMCID: PMC8827987, DOI: 10.1017/cts.2021.761.Peer-Reviewed Original ResearchImmune checkpoint inhibitorsVentricular ejection fractionLV strainCardiotoxicity groupCheckpoint inhibitorsEjection fractionProspective studyCardiac functionNormal left ventricular ejection fractionLeft ventricular ejection fractionCardiac magnetic resonance imagingCardiac magnetic resonance imaging techniquesGlobal longitudinal LV strainAbnormal troponin valuesEvidence of cardiotoxicityProportion of myocardiumLarge prospective studiesLongitudinal LV strainStudy of patientsSteady-state free precession cine imagesAbnormal cardiac functionCircumferential LV strainT2-weighted imagingMagnetic resonance imagingDysfunctional segments
2020
Left atrial late gadolinium enhancement is associated with atrial fibrillation as detected by continuous monitoring
Bertelsen L, Diederichsen S, Haugan K, Brandes A, Graff C, Krieger D, Kronborg C, Kober L, Peters D, Olesen M, Hojberg S, Vejlstrup N, Svendsen J. Left atrial late gadolinium enhancement is associated with atrial fibrillation as detected by continuous monitoring. European Heart Journal 2020, 41: ehaa946.0308. DOI: 10.1093/ehjci/ehaa946.0308.Peer-Reviewed Original ResearchImplantable loop recorderIncident AFAtrial late gadolinium enhancementLA-LGELate gadolinium enhancementLoop recorderLA volumeLeft ventricularAF episodesGadolinium enhancementLV extracellular volume fractionCardiac magnetic resonance imagingAF ablation proceduresCox regression analysisMultivariable risk prediction modelMagnetic resonance imagingRisk prediction modelExtracellular volume fractionUnknown AFLA fibrosisHazard ratioAtrial fibrillationPrognostic valueAtrial fibrosisRisk factors
2019
Prognostic and functional implications of left atrial late gadolinium enhancement cardiovascular magnetic resonance
Quail M, Grunseich K, Baldassarre LA, Mojibian H, Marieb MA, Cornfeld D, Soufer A, Sinusas AJ, Peters DC. Prognostic and functional implications of left atrial late gadolinium enhancement cardiovascular magnetic resonance. Journal Of Cardiovascular Magnetic Resonance 2019, 21: 2. PMID: 30602395, PMCID: PMC6317232, DOI: 10.1186/s12968-018-0514-3.Peer-Reviewed Original ResearchConceptsLA late gadolinium enhancementNew-onset atrial arrhythmiasLate gadolinium enhancementAtrial arrhythmiasAtrial late gadolinium enhancementLA functionAtrial fibrillationGadolinium enhancementCardiovascular magnetic resonance imagingNew atrial arrhythmiasPoor procedural outcomesLV diastolic functionLA ejection fractionVentricular mechanical functionCardiovascular magnetic resonanceMagnetic resonance imagingSeptal eDiastolic functionEjection fractionHazard ratioLA volumeProcedural outcomesPrognostic biomarkerCardiac diseasePrior history
2018
Assessment of diastolic function and atrial remodeling by MRI – validation and correlation with echocardiography and filling pressure
Seemann F, Baldassarre LA, Llanos‐Chea F, Gonzales RA, Grunseich K, Hu C, Sugeng L, Meadows J, Heiberg E, Peters DC. Assessment of diastolic function and atrial remodeling by MRI – validation and correlation with echocardiography and filling pressure. Physiological Reports 2018, 6: e13828. PMID: 30187654, PMCID: PMC6125607, DOI: 10.14814/phy2.13828.Peer-Reviewed Original ResearchConceptsLate gadolinium enhancementMagnetic resonance imagingPulmonary capillary wedge pressureLA late gadolinium enhancementCapillary wedge pressureTransthoracic echocardiographyDiastolic functionDiastolic parametersWedge pressureAtrial remodelingFilling pressureCardiovascular magnetic resonance imagingLeft atrial remodelingVentricular filling pressureAtrial late gadolinium enhancementLGE-magnetic resonance imagingDiastolic dysfunctionMedical chartsLA volumeAtrial fibrosisGadolinium enhancementResonance imagingPressure catheterizationLow interobserverEchocardiography
2014
Cardiovascular Magnetic Resonance Imaging of Scar Development Following Pulmonary Vein Isolation: A Prospective Study
Hsing J, Peters DC, Knowles BR, Manning WJ, Josephson ME. Cardiovascular Magnetic Resonance Imaging of Scar Development Following Pulmonary Vein Isolation: A Prospective Study. PLOS ONE 2014, 9: e104844. PMID: 25251403, PMCID: PMC4174508, DOI: 10.1371/journal.pone.0104844.Peer-Reviewed Original ResearchMeSH KeywordsAdultAtrial FibrillationCardiovascular SystemCatheter AblationCicatrixContrast MediaEdemaFemaleGadolinium DTPAHumansImage EnhancementLinear ModelsMagnetic Resonance ImagingMaleMiddle AgedProspective StudiesPulmonary VeinsRadiographyReproducibility of ResultsSensitivity and SpecificityTime FactorsConceptsPulmonary vein isolationCardiovascular magnetic resonanceVein isolationAtrial wall thicknessLGE enhancementLGE volumeCardiovascular magnetic resonance imagingVolume of LGEAtrial fibrillation patientsPattern of edemaSubsequent scar formationLate gadolinium enhancement (LGE) imagingMagnetic resonanceAtrial wall thickeningNon-invasive assessmentMagnetic resonance imagingEdema enhancementFibrillation patientsProspective studyPost ablationEarly edemaLGE scarScar formationEdemaResonance imaging
2013
Evaluation of current algorithms for segmentation of scar tissue from late Gadolinium enhancement cardiovascular magnetic resonance of the left atrium: an open-access grand challenge
Karim R, Housden RJ, Balasubramaniam M, Chen Z, Perry D, Uddin A, Al-Beyatti Y, Palkhi E, Acheampong P, Obom S, Hennemuth A, Lu Y, Bai W, Shi W, Gao Y, Peitgen HO, Radau P, Razavi R, Tannenbaum A, Rueckert D, Cates J, Schaeffter T, Peters D, MacLeod R, Rhode K. Evaluation of current algorithms for segmentation of scar tissue from late Gadolinium enhancement cardiovascular magnetic resonance of the left atrium: an open-access grand challenge. Journal Of Cardiovascular Magnetic Resonance 2013, 15: 105. PMID: 24359544, PMCID: PMC3878126, DOI: 10.1186/1532-429x-15-105.Peer-Reviewed Original ResearchConceptsRadio-frequency catheter ablationAtrial fibrillationTreatment of AFEnhancement cardiovascular magnetic resonance imagingLate gadolinium enhancement cardiovascular magnetic resonanceReference standardEnhancement cardiovascular magnetic resonanceCardiovascular magnetic resonance imagingPost-ablation imagesRegions of fibrosisAssessment of treatmentCardiovascular magnetic resonanceMagnetic resonance imagingPost-ablation imagingLA fibrosisCatheter ablationLGE CMR imagesCMR imagesLeft atriumTreatment stratificationScar tissueResonance imagingFibrosisStandardised evaluationKing's College London
2010
Hypertrophic Cardiomyopathy: Quantification of Late Gadolinium Enhancement with Contrast-enhanced Cardiovascular MR Imaging
Harrigan CJ, Peters DC, Gibson CM, Maron BJ, Manning WJ, Maron MS, Appelbaum E. Hypertrophic Cardiomyopathy: Quantification of Late Gadolinium Enhancement with Contrast-enhanced Cardiovascular MR Imaging. Radiology 2010, 258: 128-33. PMID: 21045187, DOI: 10.1148/radiol.10090526.Peer-Reviewed Original ResearchConceptsLate gadolinium enhancementHypertrophic cardiomyopathyGadolinium enhancementExtent of LGEMean signal intensityCardiovascular magnetic resonance imagingLGE cardiovascular magnetic resonance imagingNormal remote myocardiumVisual assessmentMagnetic resonance imagingInternal Review BoardStudy patientsMean ageBland-Altman analysisLarge cohortRemote myocardiumBody weightMore weeksPatientsSignal intensityResonance imagingGadopentetate dimeglumineMore SDsMR imagingReview boardEvaluation of Papillary Muscle Function Using Cardiovascular Magnetic Resonance Imaging in Mitral Valve Prolapse
Han Y, Peters DC, Kissinger KV, Goddu B, Yeon SB, Manning WJ, Nezafat R. Evaluation of Papillary Muscle Function Using Cardiovascular Magnetic Resonance Imaging in Mitral Valve Prolapse. The American Journal Of Cardiology 2010, 106: 243-248. PMID: 20599010, PMCID: PMC2929955, DOI: 10.1016/j.amjcard.2010.02.035.Peer-Reviewed Original ResearchConceptsMitral valve prolapseValve prolapseSystolic velocityPapillary musclesCMR imagingCardiovascular magnetic resonance imagingPapillary muscle functionHealthy adult subjectsMagnetic resonance imagingCardiovascular magnetic resonance techniquesPhase-contrast CMRAbnormal tractionElectrophysiologic stabilityPM tipsVentricular systoleMuscle functionLGE-CMRPatientsUnderlying myocardiumResonance imagingAdult subjectsProlapseCMRImagingFibrosisLate Gadolinium Enhancement of the Esophagus is Common on Cardiac MR Several Months after Pulmonary Vein Isolation: Preliminary Observations
MENG J, PETERS DC, HSING JM, CHUANG ML, CHAN J, FISH A, JOSEPHSON ME, MANNING WJ. Late Gadolinium Enhancement of the Esophagus is Common on Cardiac MR Several Months after Pulmonary Vein Isolation: Preliminary Observations. Pacing And Clinical Electrophysiology 2010, 33: 661-666. PMID: 20059713, DOI: 10.1111/j.1540-8159.2009.02671.x.Peer-Reviewed Original ResearchConceptsPulmonary vein isolationCardiovascular magnetic resonance imagingAtrial fibrillationVein isolationLGE-CMRPost-pulmonary vein isolationLate gadolinium enhancement cardiovascular magnetic resonance imagingEnhancement cardiovascular magnetic resonance imagingFrequent imaging findingsLeft atrium cavityLate gadolinium enhancementMagnetic resonance imagingEsophageal positionImaging findingsEsophageal locationGadolinium enhancementHyperenhancementNoninvasive assessmentVertebral bodyResonance imagingClinical implicationsAblation siteLonger ablation timePatientsCardiac MR
2008
Evaluating the left atrium by magnetic resonance imaging
Hauser TH, Peters DC, Wylie JV, Manning WJ. Evaluating the left atrium by magnetic resonance imaging. EP Europace 2008, 10: iii22-iii27. PMID: 18955395, PMCID: PMC2573030, DOI: 10.1093/europace/eun223.Peer-Reviewed Original ResearchConceptsLeft atriumPulmonary veinsRecurrent atrial fibrillationAtrial fibrillation ablationMagnetic resonance imagingFibrillation ablationAtrial fibrillationVariant anatomyAblation therapyMagnetic resonance imaging methodResonance imagingAtriumVeinAnatomyCatheterFibrillationImaging methodTherapyPreventionLeft atrial function and scar after catheter ablation of atrial fibrillation
Wylie JV, Peters DC, Essebag V, Manning WJ, Josephson ME, Hauser TH. Left atrial function and scar after catheter ablation of atrial fibrillation. Heart Rhythm 2008, 5: 656-662. PMID: 18452866, DOI: 10.1016/j.hrthm.2008.02.008.Peer-Reviewed Original ResearchConceptsAtrial systolic functionLA ejection fractionAtrial fibrillationCatheter ablationEjection fractionRadiofrequency ablationLeft atriumAF ablationSystolic functionLA functionCircumferential pulmonary vein isolationMaximum RA volumeRA ejection fractionCardiovascular magnetic resonance imagingPulmonary vein isolationLA scarPersistent atrial fibrillationMaximum LA volumeCine CMR imagingScar volumeMagnetic resonance imagingThromboembolic riskAtrial functionVein isolationConsecutive patients
2007
Detection of Pulmonary Vein and Left Atrial Scar after Catheter Ablation with Three-dimensional Navigator-gated Delayed Enhancement MR Imaging: Initial Experience
Peters DC, Wylie JV, Hauser TH, Kissinger KV, Botnar RM, Essebag V, Josephson ME, Manning WJ. Detection of Pulmonary Vein and Left Atrial Scar after Catheter Ablation with Three-dimensional Navigator-gated Delayed Enhancement MR Imaging: Initial Experience. Radiology 2007, 243: 690-5. PMID: 17517928, DOI: 10.1148/radiol.2433060417.Peer-Reviewed Original ResearchConceptsPulmonary veinsLeft atriumEnhancement MR imagingLeft inferior pulmonary veinMR imagingInferior pulmonary veinEnhancement magnetic resonance imagingLocal institutional review boardUnpaired t-testMagnetic resonance imagingInstitutional review boardIsolation therapyCatheter ablationAtrial fibrillationRadiofrequency ablationInteratrial septumAtrial wallEnhancement patternPatientsInitial experienceAtrial scarResonance imagingRF ablationMR imaging methodsInformed consent
2005
Invasive human magnetic resonance imaging: Feasibility during revascularization in a combined XMR suite
Dick AJ, Raman VK, Raval AN, Guttman MA, Thompson RB, Ozturk C, Peters DC, Stine AM, Wright VJ, Schenke WH, Lederman RJ. Invasive human magnetic resonance imaging: Feasibility during revascularization in a combined XMR suite. Catheterization And Cardiovascular Interventions 2005, 64: 265-274. PMID: 15736247, PMCID: PMC1317610, DOI: 10.1002/ccd.20302.Peer-Reviewed Original ResearchConceptsInvasive magnetic resonance imagingMagnetic resonance imagingIntravascular ultrasoundPeripheral angioplastyReal-time magnetic resonance imagingTherapeutic proceduresActive guidewireReceiver coilNoninvasive magnetic resonance imagingX-ray fluoroscopyMRI coilsAdvanced therapeutic proceduresIntravascular magnetic resonance imagingArtery revascularizationEligible patientsDiagnostic catheterizationRevascularization proceduresDevice dislodgmentNephrotoxic contrastPatientsResonance imagingCoilCatheter deviceGuidewire visualizationSoft tissue
2002
Catheter-Based Endomyocardial Injection With Real-Time Magnetic Resonance Imaging
Lederman RJ, Guttman MA, Peters DC, Thompson RB, Sorger JM, Dick AJ, Raman VK, McVeigh ER. Catheter-Based Endomyocardial Injection With Real-Time Magnetic Resonance Imaging. Circulation 2002, 105: 1282-1284. PMID: 11901036, PMCID: PMC1317571, DOI: 10.1161/circ.105.11.1282.Peer-Reviewed Original ResearchConceptsReal-time MRIMRI-compatible needleFirst generation prototypeRtMRI guidanceEndomyocardial injectionNeedle injectorReconstruction engineLeft ventricular cavityMagnetic resonance imagingTime magnetic resonance imagingMyocardial segmentsT MRI scannerVentricular cavityGadolinium-DTPAResonance imagingDrug deliveryLV wallCatheter navigationMultiple injectionsInjectionInjectorEngineMRI scannerCoilImaging software