The Diversity of Vaginal Microbiota Predicts Neoadjuvant Chemotherapy Responsiveness in Locally Advanced Cervical Cancer
Wang Z, Xiao R, Huang J, Qin X, Hu D, Guo E, Liu C, Lu F, You L, Sun C, Chen G. The Diversity of Vaginal Microbiota Predicts Neoadjuvant Chemotherapy Responsiveness in Locally Advanced Cervical Cancer. Microbial Ecology 2021, 84: 302-313. PMID: 34405250, DOI: 10.1007/s00248-021-01800-0.Peer-Reviewed Original ResearchMeSH KeywordsFemaleHumansMicrobiotaNeoadjuvant TherapyRNA, Ribosomal, 16SUterine Cervical NeoplasmsVaginaConceptsLocally advanced cervical cancerLocally advanced cervical cancer patientsPlatinum-based chemotherapy responseAdvanced cervical cancerCervical cancerChemotherapy responseAlpha diversityVaginal microbiotaVaginal samplesCC patientsVaginal microbiomeHealthy controlsPredicting neoadjuvant chemotherapy responsePlatinum-resistant patientsNeoadjuvant chemotherapy responseAssociated with platinum-based chemotherapy responseCervical cancer patientsVaginal microbiota diversityNeoadjuvant chemotherapyHPV infectionBeta diversityBacteroides genusChemotherapy effectCancer patientsBacteroides abundance