2022
Lower Dopamine D2/3 Receptor Availability is Associated With Worse Verbal Learning and Memory in People Who Smoke Cigarettes
Zakiniaeiz Y, Gueorguieva R, Peltier M, Roberts W, Verplaetse T, Burke C, Morris E, McKee S, Cosgrove K. Lower Dopamine D2/3 Receptor Availability is Associated With Worse Verbal Learning and Memory in People Who Smoke Cigarettes. Nicotine & Tobacco Research 2022, 25: 1047-1051. PMID: 36107715, PMCID: PMC10077933, DOI: 10.1093/ntr/ntac215.Peer-Reviewed Original ResearchConceptsCognitive functionVerbal learningPrefrontal cortexCognitive deficitsWorse verbal learningBrain-behavior relationshipsD2R availabilityDorsolateral prefrontal cortexCognitive performanceComputerized testsTask performanceCogState batteryInhibitory controlNeurocognitive testsReceptor availabilityMesocortical dopaminePositron emission tomographyDopamine D2/3 receptor availabilityMemoryCognitionD2/3 receptor availabilityDopamine releaseSmoking variablesSubject samplesDeficitsAdverse Childhood Experiences and Pathways to Violent Behavior for Women and Men
Burke C, Ellis JD, Peltier MR, Roberts W, Verplaetse TL, Phillips S, Moore KE, Marotta PL, McKee SA. Adverse Childhood Experiences and Pathways to Violent Behavior for Women and Men. Journal Of Interpersonal Violence 2022, 38: 4034-4060. PMID: 35978533, PMCID: PMC9852029, DOI: 10.1177/08862605221113012.Peer-Reviewed Original ResearchConceptsAdverse childhood experiencesViolent behaviorChildhood experiencesViolent crimeFuture violenceViolenceLatent class analysisClass analysisBiological sexTypology groupsRepresentative sampleLow adversityCrimeExperienceWomenHigh riskFour-class modelMaltreatmentChildhood maltreatmentChildhood traumaRelationshipMenAdversityRiskCurrent findingsUsing machine learning to predict heavy drinking during outpatient alcohol treatment
Roberts W, Zhao Y, Verplaetse T, Moore KE, Peltier MR, Burke C, Zakiniaeiz Y, McKee S. Using machine learning to predict heavy drinking during outpatient alcohol treatment. Alcohol Clinical And Experimental Research 2022, 46: 657-666. PMID: 35420710, PMCID: PMC9180421, DOI: 10.1111/acer.14802.Peer-Reviewed Original ResearchConceptsAlcohol use disorderHeavy drinkingTreatment outcomesInvasive assessment methodsOutpatient AUD treatmentLast monthOutpatient alcohol treatmentMultisite clinical trialAccurate clinical predictionsHeavy alcohol useSex differencesBi-weekly sessionsAlcohol treatment outcomesPatient characteristicsClinical outcomesClinical trialsClinical dataStratified analysisEffective treatmentPsychiatric disordersUse disordersAUD treatmentSubstantial sex differencesAlcohol treatmentFirst monthSexual minority disparities in opioid and benzodiazepine misuse among adults with opioid use disorder
Struble CA, Thomas K, Stenersen MR, Moore KE, Burke C, Pittman B, McKee SA. Sexual minority disparities in opioid and benzodiazepine misuse among adults with opioid use disorder. American Journal On Addictions 2022, 31: 200-209. PMID: 35243706, PMCID: PMC9117396, DOI: 10.1111/ajad.13258.Peer-Reviewed Original ResearchConceptsPast-year alcohol use disorderAlcohol use disorderSubstance use patternsBenzodiazepine misuseUse disordersConcurrent misusePast-year misuseOpioid use disorderCo-occurring alcoholSubstance use disordersTargeted prevention effortsSexual minority disparitiesConcurrent opioidBenzodiazepine useHigher oddsOpioidsElevated riskOverdose deathsConcurrent alcoholBisexual femalesDrug usePrevention effortsSubstance useSexual minority individualsBenzodiazepines
2021
Sex Differences across Retrospective Transitions in Posttraumatic Stress and Substance Use Disorders
Peltier MR, Roberts W, Verplaetse TL, Zakiniaeiz Y, Burke C, Moore KE, McKee SA. Sex Differences across Retrospective Transitions in Posttraumatic Stress and Substance Use Disorders. Journal Of Dual Diagnosis 2021, 18: 11-20. PMID: 34965199, PMCID: PMC9086923, DOI: 10.1080/15504263.2021.2016027.Peer-Reviewed Original ResearchConceptsDrug use disordersOngoing posttraumatic stress disorderSubstance use disordersSUD/PTSDPosttraumatic stress disorderNew PTSD diagnosisImpact of sexUse disordersDiagnosis of SUDPast-year substance use disorderPTSD diagnosisConcurrent substance use disordersDiagnosis of PTSDPoor treatment outcomesNational Epidemiologic SurveyBidirectional relationshipSex-specific analysesPotential sex-specific differencesTreatment outcomesThe impact of self-help groups on successful substance use treatment completion for opioid use: An intersectional analysis of race/ethnicity and sex
Stenersen MR, Thomas K, Struble C, Moore KE, Burke C, McKee S. The impact of self-help groups on successful substance use treatment completion for opioid use: An intersectional analysis of race/ethnicity and sex. Journal Of Substance Use And Addiction Treatment 2021, 136: 108662. PMID: 34840040, PMCID: PMC8940633, DOI: 10.1016/j.jsat.2021.108662.Peer-Reviewed Original ResearchConceptsOpioid useTreatment completionRace/ethnicitySelf-help groupsCompletion of treatmentTreatment Episodes DataSelf-help group participationTreatment outcomesSex disparitiesEpisode dataCurrent studyStimulant useSubstance useSexTreatmentPositive associationHigh rateBlack menEthnicityAssociationMenGroupSex and alcohol use disorder predict the presence of cancer, respiratory, and other medical conditions: Findings from the National Epidemiologic Survey on Alcohol and Related Conditions-III
Verplaetse TL, Peltier MR, Roberts W, Burke C, Moore KE, Pittman B, McKee SA. Sex and alcohol use disorder predict the presence of cancer, respiratory, and other medical conditions: Findings from the National Epidemiologic Survey on Alcohol and Related Conditions-III. Addictive Behaviors 2021, 123: 107055. PMID: 34311184, PMCID: PMC8419091, DOI: 10.1016/j.addbeh.2021.107055.Peer-Reviewed Original ResearchConceptsSignificant medical conditionsMedical conditionsNational Epidemiologic SurveyDSM-5 AUDRespiratory conditionsEpidemiologic SurveyAlcohol useU.S. National Epidemiologic SurveyRate of drinkingPresence of cancerAlcohol use disorderRelated Conditions-IIIHeavy alcohol useGreater health consequencesYears cancerProblematic alcohol useUse disordersOrgan systemsCancerHealth consequencesRelated conditionsEffective interventionsWomenConditions-IIISex
2020
A prospective study of the association between rate of nicotine metabolism and alcohol use in tobacco users in the United States
Roberts W, Marotta PL, Verplaetse TL, Peltier MR, Burke C, Ramchandani VA, McKee SA. A prospective study of the association between rate of nicotine metabolism and alcohol use in tobacco users in the United States. Drug And Alcohol Dependence 2020, 216: 108210. PMID: 32805549, PMCID: PMC7609495, DOI: 10.1016/j.drugalcdep.2020.108210.Peer-Reviewed Original ResearchConceptsNicotine metabolite ratioRisk factorsAlcohol useTobacco usersNicotine metabolismTrans-3'-HydroxycotinineWave 1Biochemical risk factorsAlcohol consumption amountCurrent tobacco usersNicotine metabolism rateAssociated health outcomesSex differencesAlcohol use outcomesCigarette smokersNicotine exposureProspective studyOdds ratioTobacco useDrinking statusHealth StudyAlcohol consumptionNicotine useMetabolite ratiosHealth outcomes