2024
Early Experience with Diclofenac Topical Gel for Moderate to Severe Post-Ablation Phlebitis
Melesio F, Mesa-Damiano M, Quinones-Rodriguez J, Staudaher S, Ochoa Chaar C, Rodriguez L. Early Experience with Diclofenac Topical Gel for Moderate to Severe Post-Ablation Phlebitis. Journal Of Vascular Surgery Venous And Lymphatic Disorders 2024, 101994. PMID: 39419265, DOI: 10.1016/j.jvsv.2024.101994.Peer-Reviewed Original ResearchNon-steroidal anti-inflammatory drugsDiclofenac topical gelTopical gelNumeric Pain Rating ScaleLocalized pain reductionSignificant pain reliefPain rating scaleFirst-line treatmentRetrospective cohort studyTopical diclofenac gelAnti-inflammatory drugsNPRS scoreDiclofenac gelPain reductionInitial treatmentPain reliefNSAID groupPost-ablationAlone groupCohort studyPhlebitisPatientsRating ScaleTreatmentFour-time intervalsThe Incidence and Impact of Cardiac Function Decline after Lower Extremity Revascularization
Jamil Y, Huttler J, Alameddine D, Wu Z, Mena-Hurtado C, Velazquez E, Guzman R, Ochoa Chaar C. The Incidence and Impact of Cardiac Function Decline after Lower Extremity Revascularization. Annals Of Vascular Surgery 2024 PMID: 39343374, DOI: 10.1016/j.avsg.2024.07.119.Peer-Reviewed Original ResearchCardiac functional declineStable cardiac functionLower extremity revascularizationPeripheral arterial diseaseCardiac functionFollow-upExtremity revascularizationFunctional declineElectronic records of patientsKaplan-Meier analysisRecords of patientsMode of revascularizationAdverse limb eventsLower-extremity revascularizationTransthoracic echocardiogramReintervention rateHeart failureDiabetes mellitusPeriprocedural bleedingPatient characteristicsArtery diseasePatientsLimb eventsIncreased mortalityRevascularizationAtherectomy – The Options, the Evidence, and When Should It Be Used
Pinto P, Ochoa Chaar C. Atherectomy – The Options, the Evidence, and When Should It Be Used. Annals Of Vascular Surgery 2024, 107: 127-135. PMID: 38583766, DOI: 10.1016/j.avsg.2023.12.104.Peer-Reviewed Original ResearchPeripheral vascular interventionsEndovascular techniquesLack of level 1 evidenceFirst-line therapyLevel 1 evidenceOffice-based laboratoriesComplex atherosclerotic lesionsProspective studyDissection riskEndovascular technologyBailout stentingArtery calcificationAmbulatory surgery centersSurgery centersModerate disease burdenVascular interventionsPlaque modificationDisease burdenAtherectomyAtherosclerotic lesionsPatientsTheoretical benefitsPractitioner preferencesAtherectomy technologiesTherapyThe Use and Impact of Cilostazol on Patients Undergoing Endovascular Peripheral Interventions
Alameddine D, Damara F, Pinto Rodriguez P, Huttler J, Slade M, Arhuidese I, Aboian E, Ochoa Chaar C. The Use and Impact of Cilostazol on Patients Undergoing Endovascular Peripheral Interventions. Annals Of Vascular Surgery 2024, 103: 47-57. PMID: 38387798, DOI: 10.1016/j.avsg.2023.12.071.Peer-Reviewed Original ResearchImpact of cilostazolPeripheral vascular interventionsPeripheral arterial diseaseTreatment of intermittent claudicationRates of long-term mortalityPeripheral vascular interventional proceduresKaplan-Meier methodCongestive heart failureLong-term mortalityLong-term outcomesEndovascular peripheral interventionsRenal complicationsPatient demographicsBaseline characteristicsHeart failureDiabetes mellitusArtery diseaseIntermittent claudicationCilostazolPatientsVascular interventionsPeripheral interventionsClaudicationOutcomesIntervention
2023
A comparison of below-knee vs above-knee endovenous ablation of varicose veins
Bai H, Gokani V, Storch J, Kibrik P, Aziz F, Sachdev U, Fukaya E, Chaar C, T. A, Ting W. A comparison of below-knee vs above-knee endovenous ablation of varicose veins. Journal Of Vascular Surgery Venous And Lymphatic Disorders 2023, 12: 101679. PMID: 37708939, PMCID: PMC11523341, DOI: 10.1016/j.jvsv.2023.08.018.Peer-Reviewed Original ResearchVenous Clinical Severity ScorePatient-reported outcomesKnee treatmentKnee interventionsComposite scoreVascular Quality Initiative Varicose Vein RegistryMultivariable logistic regression analysisClinical severity scoreDeep vein thrombosisMultivariable logistic regressionOdds of improvementLogistic regression analysisQuality of lifeVein ablationVein thrombosisAnatomic distributionSeverity scoreMultivariable modelTreatment outcomesVaricose veinsHigher oddsVein treatmentPatientsLogistic regressionCategorical variablesSystematic review of inferior vena cava atresia
Saab K, Brahmandam A, Brackett A, Desai M, Dardik A, Guzman R, Chaar C. Systematic review of inferior vena cava atresia. Journal Of Vascular Surgery Venous And Lymphatic Disorders 2023, 11: 1253-1264. PMID: 37453547, DOI: 10.1016/j.jvsv.2023.07.002.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsDeep vein thrombosisIVC atresiaCongenital anomaliesLeg painMost patientsDevelopment of DVTSystematic reviewAcceptable mid-term resultsInferior vena cava atresiaEndovascular surgical interventionsMortality of patientsOutcomes of patientsMid-term resultsRare venous anomalyTerms of patencyVein thrombosisSymptomatic reliefVenous anomaliesIliac veinInferior venaSurgical interventionMean ageTreatment groupsPatientsAtresia
2021
Association Between Preexisting Versus Newly Identified Atrial Fibrillation and Outcomes of Patients With Acute Pulmonary Embolism
Bikdeli B, Jiménez D, del Toro J, Piazza G, Rivas A, Fernández‐Reyes J, Sampériz Á, Otero R, Suriñach J, Siniscalchi C, Martín‐Guerra J, Castro J, Muriel A, Lip G, Goldhaber S, Monreal M, Monreal M, Prandoni P, Brenner B, Farge‐Bancel D, Barba R, Di Micco P, Bertoletti L, Schellong S, Tzoran I, Reis A, Bosevski M, Bounameaux H, Malý R, Verhamme P, Caprini J, Bui H, Adarraga M, Agud M, Aibar J, Aibar M, Amado C, Arcelus J, Baeza C, Ballaz A, Barba R, Barbagelata C, Barrón M, Barrón‐Andrés B, Blanco‐Molina Á, Botella E, Camon A, Cañas I, Casado I, Castro J, Chasco L, Criado J, de Ancos C, de Miguel J, del Toro J, Demelo‐Rodríguez P, Díaz‐Peromingo J, Di Campli M, Díez‐Sierra J, Domínguez I, Escribano J, Falgá C, Farfán‐Sedano A, Fernández‐Capitán C, Fernández‐Reyes J, Fidalgo M, Flores K, Font C, Font L, Francisco I, Gabara C, Galeano‐Valle F, Galindo D, García M, García‐Bragado F, de Herreros M, García‐Hernáez R, García‐Mullor M, García‐Raso A, Gavín‐Sebastián O, Gil‐Díaz A, Gómez‐Cuervo C, Grau E, Guirado L, Gutiérrez J, Hernández‐Blasco L, Hernando E, Herreros M, Jara‐Palomares L, Jaras M, Jiménez D, Jiménez R, Joya M, León J, Lima J, Llamas P, Lobo J, López‐Jiménez L, López‐Miguel P, López‐Núñez J, López‐Reyes R, López‐Ruiz A, López‐Sáez J, Lorenzo A, Madridano O, Maestre A, Marchena P, del Pozo M, Martín‐Guerra J, Martín‐Martos F, Mella C, Mellado M, Mercado M, Moisés J, Monreal M, del Valle Morales M, Muñoz‐Blanco A, Muñoz‐Rivas N, Navas M, Nieto J, Núñez‐Fernández M, Obispo B, Olid M, Olivares M, Orcastegui J, Ortega‐Michel C, Osorio J, Otalora S, Otero R, Parra P, Parra V, Pedrajas J, Pellejero G, Porras J, Portillo J, Riera‐Mestre A, Rivas A, Rivera‐Civico F, Rodríguez‐Chiaradía D, Rodríguez‐Cobo A, Rodríguez‐Matute C, Rogado J, Roig S, Rosa V, Ruiz‐Artacho P, Ruiz‐Giménez N, Ruiz‐Ruiz J, Ruiz‐Sada P, Salgueiro G, Sánchez‐Martínez R, Sánchez‐Muñoz‐Torrero J, Sancho T, Sirisi M, Soler S, Suriñach J, Tirado R, Torres M, Tolosa C, Trujillo‐Santos J, Uresandi F, Valero B, Valle R, Vela J, Vidal G, Villares P, Zamora C, Gutiérrez P, Vázquez F, Engelen M, Vanassche T, Verhamme P, Hirmerova J, Malý R, Salgado E, Abdallah N, Bertoletti L, Bura‐Riviere A, Crichi B, Debourdeau P, Olivier E, Falvo N, Farge‐Bancel D, Galliazzo S, Helfer H, Mahé I, Moustafa F, Poenou G, Schellong S, Braester A, Brenner B, Tzoran I, Bilora F, Bucherini E, Ciammaichella M, Di Micco P, Imbalzano E, Maida R, Mastroiacovo D, Pace F, Pesavento R, Pomero F, Prandoni P, Quintavalla R, Rocci A, Romualdi R, Siniscalchi C, Tufano A, Visonà A, Zalunardo B, Gibietis V, Kigitovica D, Skride A, Fonseca S, Martins F, Meireles J, Bosevski M, Bounameaux H, Mazzolai L, Bikdeli B, Caprini J, Tafur A, Ochoa‐Chaar C, Weinberg I, Wilkins H, Bui H. Association Between Preexisting Versus Newly Identified Atrial Fibrillation and Outcomes of Patients With Acute Pulmonary Embolism. Journal Of The American Heart Association 2021, 10: e021467. PMID: 34459215, PMCID: PMC8649245, DOI: 10.1161/jaha.121.021467.Peer-Reviewed Original ResearchConceptsAcute pulmonary embolismIncident atrial fibrillationPulmonary embolismAtrial fibrillationAcute symptomatic pulmonary embolismNew incident atrial fibrillationTiming of AFNew atrial fibrillationOutcomes of patientsSymptomatic pulmonary embolismAdverse clinical outcomesBackground Atrial fibrillationAF onsetCause mortalityMultivariable adjustmentIschemic strokeClinical outcomesMultivariable analysisAdverse outcomesPatientsMortalityStrokeEmbolismOutcomesFibrillationAortic remodeling and competitive flow after surgical treatment of aortic dissection
Chan SM, Brahmandam A, Cardella JA, Elefteriades J, Setaro JF, Mangi AA, Chaar C. Aortic remodeling and competitive flow after surgical treatment of aortic dissection. Journal Of Vascular Surgery Cases And Innovative Techniques 2021, 7: 404-407. PMID: 34278070, PMCID: PMC8261546, DOI: 10.1016/j.jvscit.2021.05.009.Peer-Reviewed Original ResearchAortic remodelingCompetitive flowAortic dissectionAcute lower extremity ischemiaExtra-anatomic conduitLower extremity ischemiaAxillobifemoral bypassExtremity ischemiaSurgical treatmentPatient outcomesVascular phenomenaNative aortaDissectionRemodelingPresent reportMalperfusionRecanalizationIschemiaThrombosisPatientsAortaReinstitutionBypassEmergent percutaneous chimney endovascular aortic repair of a secondary aortoenteric fistula in the setting of a solitary kidney
Chen JF, Chaar C, Cardella J, Dardik A, Guzman RJ, Nassiri N. Emergent percutaneous chimney endovascular aortic repair of a secondary aortoenteric fistula in the setting of a solitary kidney. Journal Of Vascular Surgery Cases And Innovative Techniques 2021, 7: 253-257. PMID: 33997566, PMCID: PMC8095080, DOI: 10.1016/j.jvscit.2021.01.009.Peer-Reviewed Original ResearchSecondary aortoenteric fistulaAortoenteric fistulaAortic surgerySolitary kidneyEndovascular repairChimney endovascular aortic repairUrgent endovascular repairExtra-anatomic bypassOpen aortic surgeryEndovascular aortic repairEndovascular aneurysm repairAlternative treatment modalityGraft excisionAortic repairAneurysm repairSeptic shockLethal complicationTreatment modalitiesPoor candidatesSitu reconstructionFistulaTraditional treatmentPatientsSurgeryKidneyDiagnostic and Technical Challenges in the Care of a Complex Patient With Post-Thrombotic Syndrome
Chan SM, Lee A, Roy B, Chaar CIO. Diagnostic and Technical Challenges in the Care of a Complex Patient With Post-Thrombotic Syndrome. Vascular And Endovascular Surgery 2021, 55: 515-518. PMID: 33563142, DOI: 10.1177/1538574421995020.Peer-Reviewed Original ResearchConceptsPost-thrombotic syndromeDeep vein thrombosisVein thrombosisComplex patientsIliofemoral deep vein thrombosisExtensive deep vein thrombosisAccurate patient evaluationVenous recanalizationEndovascular treatmentSymptomatic reliefPatient evaluationMorbid conditionsClinical successSyndromePatientsThrombosisAlternative accessCareRecanalizationSymptomsStrokeStrategies to Minimize Iodinated Contrast Volume in Patients with Chronic Kidney Disease Undergoing Peripheral Vascular Interventions
Lee SR, Dardik A, Chaar CIO. Strategies to Minimize Iodinated Contrast Volume in Patients with Chronic Kidney Disease Undergoing Peripheral Vascular Interventions. Annals Of Vascular Surgery 2021, 73: 490-495. PMID: 33556507, DOI: 10.1016/j.avsg.2021.01.081.Peer-Reviewed Original ResearchConceptsPeripheral vascular interventionsChronic kidney diseaseVascular interventionsPostcontrast acute kidney injuryChronic limb threatening ischemiaSuccessful endovascular revascularizationAcute kidney injuryCKD stage 4Limb threatening ischemiaPC-AKIEndovascular revascularizationKidney injuryUse of ICMContrast volumeKidney diseaseIntravascular lesionsContrast mediumPatientsStage 4InterventionRiskRevascularizationIschemiaInjuryTherapy
2020
Correlation of venous symptoms with iliac vein stenosis on magnetic resonance imaging
Aurshina A, Huber S, Deng Y, Attaran R, Nassiri N, Dardik A, Ochoa Chaar CI. Correlation of venous symptoms with iliac vein stenosis on magnetic resonance imaging. Journal Of Vascular Surgery Venous And Lymphatic Disorders 2020, 9: 1291-1296.e1. PMID: 33387666, DOI: 10.1016/j.jvsv.2020.12.077.Peer-Reviewed Original ResearchConceptsIliac vein stenosisMagnetic resonance imagingElectronic medical recordsVenous symptomsVein stenosisEMR reviewResonance imagingLower extremity venous diseaseTelephone survey resultsConsecutive adult patientsThird of patientsBrief telephone surveyAdult patientsPatient characteristicsConsecutive patientsVenous stenosisVenous diseaseRetrospective studyMean ageMedical recordsStenosisPatientsMRI scansSymptomsPelvisOutcomes of treatment with paclitaxel-coated devices for peripheral arterial disease
Kim TI, Kiwan G, Mohamedali A, Zhang Y, Mena-Hurtado C, Mojibian H, Guzman RJ, Ochoa Chaar CI. Outcomes of treatment with paclitaxel-coated devices for peripheral arterial disease. Journal Of Vascular Surgery 2020, 73: 911-917. PMID: 33038480, DOI: 10.1016/j.jvs.2020.08.146.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAmputation, SurgicalCardiovascular AgentsCoated Materials, BiocompatibleDrug-Eluting StentsEndovascular ProceduresFemaleHumansLimb SalvageMaleMiddle AgedPaclitaxelPeripheral Arterial DiseaseProsthesis DesignRetreatmentRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeVascular PatencyConceptsPaclitaxel-coated devicesPeripheral artery diseaseCause of mortalityPCD useRisk of mortalityCumulative doseFemoropopliteal peripheral artery diseaseKaplan-Meier survival curvesLong-term mortalityPeripheral arterial diseaseCox regression analysisDrug-coated balloonsOutcome of treatmentDrug-eluting stentsMajor amputationPrimary patencyReintervention rateArtery diseaseArterial diseaseRandomized trialsOpen surgeryPresent studySingle institutionEndovascular interventionPatientsDiscrepancy in Outcomes after Revascularization for Chronic Limb-Threatening Ischemia Warrants Separate Reporting of Rest Pain and Tissue Loss
Brahmandam A, Gholitabar N, Cardella J, Nassiri N, Dardik A, Georgi M, Ochoa Chaar CI. Discrepancy in Outcomes after Revascularization for Chronic Limb-Threatening Ischemia Warrants Separate Reporting of Rest Pain and Tissue Loss. Annals Of Vascular Surgery 2020, 70: 237-244. PMID: 32659417, DOI: 10.1016/j.avsg.2020.06.057.Peer-Reviewed Original ResearchMeSH KeywordsAgedAmputation, SurgicalBenchmarkingChronic DiseaseComorbidityDatabases, FactualFemaleHospital MortalityHumansInpatientsIntermittent ClaudicationIschemiaMalePeripheral Arterial DiseaseQuality Indicators, Health CareRetrospective StudiesRisk AssessmentRisk FactorsTreatment OutcomeUnited StatesVascular Surgical ProceduresConceptsLower extremity revascularizationCharlson Comorbidity IndexRest painMajor amputationInpatient mortalityTissue lossEndovascular lower extremity revascularizationWorse short-term outcomesShort-term outcomesNational Inpatient SampleLength of stayMultivariable regression analysisComorbidity indexExtremity revascularizationPatient characteristicsMultivariable analysisInpatient SampleHigh comorbidityMean costPatientsAmputationMortalityTL groupOutcomesRevascularization
2019
Intraoperative Ultrasound Guidance for Banding of an Arteriovenous Fistula Causing High Cardiac Output Heart Failure
Turner AD, Chen M, Dahl N, Scoutt L, Dardik A, Ochoa Chaar C. Intraoperative Ultrasound Guidance for Banding of an Arteriovenous Fistula Causing High Cardiac Output Heart Failure. Annals Of Vascular Surgery 2019, 66: 665.e5-665.e8. PMID: 31863947, DOI: 10.1016/j.avsg.2019.12.011.Peer-Reviewed Case Reports and Technical NotesConceptsEnd-stage renal diseaseArteriovenous fistulaHigh cardiac output heart failureHigh cardiac output failureHigh-output cardiac failureOutput cardiac failureIntraoperative ultrasound guidanceRare complicationCardiac failureHeart failureRenal diseaseCase reportCardiac functionUltrasound guidanceIntraoperative ultrasoundFlow volumeOutput failureFistulaPatientsGradual declineFailureBandingComplicationsHemodialysisHigh flow volumesTreatment of superior vena cava syndrome with kissing brachiocephalic stents and exchange of pacemaker leads
Ochoa Chaar C, Gholitabar N, Rezek I, Luciano R, Clancy J. Treatment of superior vena cava syndrome with kissing brachiocephalic stents and exchange of pacemaker leads. Journal Of Vascular Surgery Venous And Lymphatic Disorders 2019, 8: 143-144. PMID: 31231057, DOI: 10.1016/j.jvsv.2019.04.009.Peer-Reviewed Original ResearchConceptsSuperior vena cava syndromeVena cava syndromeRecurrence of symptomsUpper extremity accessElectrophysiology teamMultidisciplinary managementKissing stentsBalloon angioplastySuperior venaBrachiocephalic veinComplex patientsHemodialysis accessCase reportChallenging complicationVascular surgeryPatientsSyndromeJoint proceduresPacemakerMultiple attemptsStentsAngioplastyHemodialysisComplicationsVena
2017
Whole-exome sequencing in evaluation of patients with venous thromboembolism
Lee EJ, Dykas DJ, Leavitt AD, Camire RM, Ebberink E, García de Frutos P, Gnanasambandan K, Gu SX, Huntington JA, Lentz SR, Mertens K, Parish CR, Rezaie AR, Sayeski PP, Cromwell C, Bar N, Halene S, Neparidze N, Parker TL, Burns AJ, Dumont A, Yao X, Chaar CIO, Connors JM, Bale AE, Lee AI. Whole-exome sequencing in evaluation of patients with venous thromboembolism. Blood Advances 2017, 1: 1224-1237. PMID: 29296762, PMCID: PMC5728544, DOI: 10.1182/bloodadvances.2017005249.Peer-Reviewed Original ResearchWhole-exome sequencingVenous thromboembolismStudy patientsThrombophilia panelVTE patientsHeritable thrombophiliaThrombophilia testingDisease-causing genetic variantsEvaluation of patientsControl patientsThrombophilia mutationsProtein modelingThrombotic historyProtein structurePatientsThrombophilia genesVTE pathogenesisWES variantsUnknown significanceThrombophiliaGenetic variantsGenesPrior reportsSequencingThromboembolism
2015
Management of isolated calf vein thrombosis in cancer patients
Brahmandam AS, Brownson K, Skrip L, Parker T, Indes J, Sarac T, Dardik A, Chaar CI. Management of isolated calf vein thrombosis in cancer patients. Vascular 2015, 24: 64-69. PMID: 25957344, DOI: 10.1177/1708538115584726.Peer-Reviewed Original ResearchConceptsCalf vein thrombosisIsolated calf vein thrombosisVein thrombosisHistory of cancerCancer patientsBenefits of anticoagulationInitiation of anticoagulationPatient risk factorsRetrospective chart reviewLong-term recurrenceChart reviewConsecutive patientsTreatment modalitiesRisk factorsThrombosisHigh incidencePatientsAnticoagulationOlder ageCancerMortalityIncidenceAnatomical characteristicsTreatmentRecurrence
2010
Cologastric fistula with a foreign body in a patient with Crohn's disease.
McGillicuddy EA, Chaar CI, Flynn C, Villalona G, Longo WE. Cologastric fistula with a foreign body in a patient with Crohn's disease. The Yale Journal Of Biology And Medicine 2010, 83: 113-7. PMID: 20885896, PMCID: PMC2946122.Peer-Reviewed Original Research
2009
Endovascular aneurysm repair is associated with less malnutrition than open abdominal aortic aneurysm repair
Chaar CI, Fitzgerald TN, Dewan M, Huddle M, Schlosser FJ, Perkal M, Muhs BE, Dardik A. Endovascular aneurysm repair is associated with less malnutrition than open abdominal aortic aneurysm repair. The American Journal Of Surgery 2009, 198: 623-627. PMID: 19887189, PMCID: PMC2774903, DOI: 10.1016/j.amjsurg.2009.07.022.Peer-Reviewed Original ResearchConceptsEndovascular aneurysm repairAbdominal aortic aneurysm repairAortic aneurysm repairAneurysm repairPostoperative malnutritionAAA repairOpen repairOpen abdominal aortic aneurysm repairIntensive care unit stayNutritional Risk Index scoresVeterans Affairs Connecticut Healthcare SystemNutritional Risk IndexDuration of intubationLength of hospitalizationOpen AAA repairRecords of patientsRisk index scoreLess malnutritionUnit stayAlbumin levelsPrimary outcomePatientsIndex scoreMalnutritionHealthcare system