2023
Evidence Accumulates: Patients with Ascending Aneurysms Are Strongly Protected from Atherosclerotic Disease
Waldron C, Zafar M, Ziganshin B, Weininger G, Grewal N, Elefteriades J. Evidence Accumulates: Patients with Ascending Aneurysms Are Strongly Protected from Atherosclerotic Disease. International Journal Of Molecular Sciences 2023, 24: 15640. PMID: 37958625, PMCID: PMC10650782, DOI: 10.3390/ijms242115640.Peer-Reviewed Original ResearchConceptsThoracic aortic aneurysmAortic aneurysmCarotid intima-media thicknessLow-density lipoprotein levelsIntima-media thicknessDevelopment of atherosclerosisMatrix metalloproteinase proteinsAscending aneurysmAortic calcificationAtherosclerotic diseaseLipoprotein levelsMyocardial infarctionLeading causeAneurysmsMetalloproteinase proteinsGrowth factorProtective relationshipDiseasePossible mechanismCurrent understandingMorbidityInfarctionAtherosclerosisPatientsPathophysiology
2015
Atenolol versus Losartan in Marfan's Syndrome
Ziganshin B, Mukherjee S, Elefteriades J. Atenolol versus Losartan in Marfan's Syndrome. New England Journal Of Medicine 2015, 372: 977-981. PMID: 25738681, DOI: 10.1056/nejmc1500128.Peer-Reviewed Original Research
2014
Surgical management of thoracoabdominal aneurysms
Ziganshin BA, Elefteriades JA. Surgical management of thoracoabdominal aneurysms. Heart 2014, 100: 1577. PMID: 25092876, DOI: 10.1136/heartjnl-2013-305131.Peer-Reviewed Original ResearchConceptsThoracoabdominal aneurysmsSurgical managementApplication of hypothermiaCerebrospinal fluid drainageType of treatmentParaplegia ratePostoperative mortalityHospital stayComplication rateSurgical treatmentHeart bypassHybrid repairTreatment adjunctsMorbid conditionsFluid drainageHigh mortalityTAAASignificant decreaseAneurysmsTreatmentMortalityNeuromonitoringPatientsStayAortaStraight deep hypothermic circulatory arrest for cerebral protection during aortic arch surgery: Safe and effective
Ziganshin BA, Rajbanshi BG, Tranquilli M, Fang H, Rizzo JA, Elefteriades JA. Straight deep hypothermic circulatory arrest for cerebral protection during aortic arch surgery: Safe and effective. Journal Of Thoracic And Cardiovascular Surgery 2014, 148: 888-900. PMID: 25052822, DOI: 10.1016/j.jtcvs.2014.05.027.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAorta, ThoracicAortic Aneurysm, ThoracicAortic DissectionCerebrovascular CirculationChi-Square DistributionCirculatory Arrest, Deep Hypothermia InducedFemaleHumansKaplan-Meier EstimateLogistic ModelsMaleMiddle AgedMultivariate AnalysisOdds RatioOperative TimePostoperative ComplicationsRetrospective StudiesRisk FactorsTime FactorsTreatment OutcomeVascular Surgical ProceduresYoung AdultConceptsDeep hypothermic circulatory arrestMinutes of DHCAStraight deep hypothermic circulatory arrestAortic arch surgeryHypothermic circulatory arrestCerebral protectionStroke rateArch surgeryCirculatory arrestAortic archPostoperative stroke rateSignificant postoperative mortalityComposite adverse outcomeOverall stroke rateExtensive clinical experienceDHCA durationElective mortalityPostoperative mortalityNeurologic sequelaeExperienced centersRenal failureAortic dissectionConsecutive patientsOverall mortalityDHCA time
2013
Midterm experience with modified Cabrol procedure: Safe and durable for complex aortic root replacement
Ziganshin BA, Williams FE, Tranquilli M, Elefteriades JA. Midterm experience with modified Cabrol procedure: Safe and durable for complex aortic root replacement. Journal Of Thoracic And Cardiovascular Surgery 2013, 147: 1233-1239. PMID: 23628496, DOI: 10.1016/j.jtcvs.2013.03.027.Peer-Reviewed Original ResearchConceptsDacron interposition graftComposite graft replacementCabrol techniqueInterposition graftGraft replacementCoronary ostiumSocial Security Death IndexMain aortic graftTotal late mortalityAortic root replacementBetter survival rateActuarial survivalCoronary aneurysmsCoronary anomaliesCoronary buttonsMidterm experienceCoronary reimplantationLate mortalityRoot replacementAortic graftCabrol procedureCoronary graftsAortic databaseDeath IndexEarly mortality
2010
Does Straight Deep Hypothermic Circulatory Arrest Suffice for Brain Preservation in Aortic Surgery?
Ziganshin B, Elefteriades JA. Does Straight Deep Hypothermic Circulatory Arrest Suffice for Brain Preservation in Aortic Surgery? Seminars In Thoracic And Cardiovascular Surgery 2010, 22: 291-301. PMID: 21549269, DOI: 10.1053/j.semtcvs.2011.01.011.Peer-Reviewed Original Research