2008
Genomic imprinting of IGF2 in marsupials is methylation dependent
Lawton BR, Carone BR, Obergfell CJ, Ferreri GC, Gondolphi CM, VandeBerg JL, Imumorin I, O'Neill RJ, O'Neill MJ. Genomic imprinting of IGF2 in marsupials is methylation dependent. BMC Genomics 2008, 9: 205. PMID: 18454865, PMCID: PMC2386826, DOI: 10.1186/1471-2164-9-205.Peer-Reviewed Original ResearchConceptsMatrix attachment regionsGenomic imprintingSpecific CpG residuesParent-specific methylationSouth American opossum Monodelphis domesticaAllele-specific patternsMarsupial genomesTranscriptional silencingEvolutionary originImprinted lociImprinted genesSelective forcesCpG residuesEutherian mammalsBiallelic expressionDNA methylationRegulatory featuresCpG methylationKilobase regionOpossum Monodelphis domesticaKey regulatorPaternal Igf2 alleleIgf2 alleleMaternal alleleImprinting mechanism
2007
Physical mapping of the IGF2 locus in the South American opossum Monodelphis domestica
Lawton BR, Obergfell C, O’Neill R, O’Neill M. Physical mapping of the IGF2 locus in the South American opossum Monodelphis domestica. Cytogenetic And Genome Research 2007, 116: 130-131. PMID: 17268191, DOI: 10.1159/000097431.Peer-Reviewed Original ResearchConceptsSouth American opossum Monodelphis domesticaGenomic imprintingLarge-scale genome sequencing effortsOpossum Monodelphis domesticaGenome sequencing effortsInsulin-like growth factor II geneMonodelphis domesticaGrowth factor II geneFactor II geneGene functionModel organismsGene regulationSequencing effortsPhysical mappingIGF2 locusRegulatory mechanismsM. domesticaMarsupialsDomesticaImprintingRegulationGenesLociOrganismsMechanism
2005
Allelic expression of IGF2 in live-bearing, matrotrophic fishes
Lawton BR, Sevigny L, Obergfell C, Reznick D, O’Neill R, O’Neill M. Allelic expression of IGF2 in live-bearing, matrotrophic fishes. Development Genes And Evolution 2005, 215: 207-212. PMID: 15654625, DOI: 10.1007/s00427-004-0463-8.Peer-Reviewed Original ResearchConceptsInsulin-like growth factor 2Parent-specific gene expressionGenomic imprinting predictsGrowth regulatory genesMatrotrophic fishPoeciliopsis prolificaTranscriptional silencingHeterandria formosaRegulatory genesFish speciesAllelic expressionEmbryonic developmentIGF2 activityGene expressionPlacental animalsDevelopmental expressionGrowth factor 2GenesParental investmentEmbryonic growthSpeciesFactor 2ExpressionVertebratesEutherians