Stiffness Dependent Separation of Cells in a Microfluidic Device
Wang G, Mao W, Byler R, Patel K, Henegar C, Alexeev A, Sulchek T. Stiffness Dependent Separation of Cells in a Microfluidic Device. PLOS ONE 2013, 8: e75901. PMID: 24146787, PMCID: PMC3797716, DOI: 10.1371/journal.pone.0075901.Peer-Reviewed Original ResearchMeSH KeywordsCell Line, TumorCell SeparationCell SizeElasticityEpithelial CellsEquipment DesignErythrocytesHardnessHumansJurkat CellsK562 CellsMicrofluidic Analytical TechniquesMicroscopy, Atomic ForceConceptsMicrofluidic channelMicrofluidic separation techniquesContinuous cell separationAtomic force microscopySecondary flowNew microfluidic techniqueDifferent stiffnessMechanical stiffnessMicrofluidic deviceMicrofluidic techniquesStiffnessForce microscopyMicrofluidic approachCell perpendicularSeparation techniquesProcessing throughputPhysical principlesChannel axisMicrochannels