2024
Multi-modality imaging for assessment of the microcirculation in peripheral artery disease: Bench to clinical practice
Callegari S, Feher A, Smolderen K, Mena-Hurtado C, Sinusas A. Multi-modality imaging for assessment of the microcirculation in peripheral artery disease: Bench to clinical practice. American Heart Journal Plus Cardiology Research And Practice 2024, 42: 100400. PMID: 38779485, PMCID: PMC11108852, DOI: 10.1016/j.ahjo.2024.100400.Peer-Reviewed Original ResearchPeripheral arterial diseaseMicrovascular diseasePeripheral microcirculationArtery diseaseEvaluation of response to therapyResponse to therapyManagement of peripheral arterial diseaseImprove risk stratificationOutcomes of peripheral artery diseaseAssessment of perfusionPathophysiology of peripheral arterial diseaseRisk of mortalityMolecular imaging studiesMulti-modal imagesPredictors of amputationRisk stratificationPre-clinicalImaging studiesClinical perfusionProcedural treatmentsClinical practicePersonalized managementMicrocirculationDiseasePerfusionDeep learning-based epicardial adipose tissue measurement, maximizing prognostic information from attenuation correction imaging
Shanbhag A, Miller R, Killekar A, Lemley M, Bednarski B, Van Kriekinge S, Kavanagh P, Feher A, Miller E, Bateman T, Liang J, Builoff V, Berman D, Dey D, Slomka P. Deep learning-based epicardial adipose tissue measurement, maximizing prognostic information from attenuation correction imaging. Progress In Biomedical Optics And Imaging 2024, 12930: 129300b-129300b-6. DOI: 10.1117/12.3007914.Peer-Reviewed Original ResearchEpicardial adipose tissueUngated CTMyocardial infarctionEAT volumeRisk stratificationComputed tomographyEAT volume measurementEpicardial adipose tissue measurementsEpicardial adipose tissue volumeAssociated with risk of cardiovascular eventsRisk of cardiovascular eventsMedian follow-upIncreased risk of deathGated computed tomographyImprove risk stratificationAdipose tissue measurementsAssociated with riskRisk of deathAttenuation correction imagesGated CTChest CTNo significant differencePrognostic informationCardiovascular eventsFollow-up
2019
Molecular Imaging of the Heart
Boutagy NE, Feher A, Alkhalil I, Umoh N, Sinusas AJ. Molecular Imaging of the Heart. 2019, 9: 477-533. PMID: 30873600, DOI: 10.1002/cphy.c180007.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsCardiovascular diseaseRisk stratificationCardiovascular molecular imagingMultimodality cardiovascular imagingIschemic heart failureMolecular imagingMolecular imaging targetsPositron emission tomographySingle photon emissionNumerous cardiovascular diseasesClinical molecular imagingEjection fractionHeart failureMedical therapySystemic diseaseMyocardial infarctionPathophysiological changesCardiac functionEarly diagnosisDisease processCardiac arrhythmiasEmission tomographyCardiovascular imagingImaging strategiesPhoton emission
2018
Development and Validation of a Clinical Score for Cardiovascular Risk Stratification of Long‐Term Childhood Cancer Survivors
Oikonomou EK, Athanasopoulou SG, Kampaktsis PN, Kokkinidis DG, Papanastasiou CA, Feher A, Steingart RM, Oeffinger KC, Gupta D. Development and Validation of a Clinical Score for Cardiovascular Risk Stratification of Long‐Term Childhood Cancer Survivors. The Oncologist 2018, 23: 965-973. PMID: 29593100, PMCID: PMC6156177, DOI: 10.1634/theoncologist.2017-0502.Peer-Reviewed Original ResearchConceptsLong-term childhood cancer survivorsChildhood cancer survivorsCardiovascular risk stratificationCardiovascular mortalityCancer survivorsRisk scoreCardiovascular riskRisk stratificationRisk of CVMTreatment-related adverse eventsAdverse cardiovascular eventsRisk stratification toolSimple risk scoreCongestive heart failureCumulative incidence rateEnd Results ProgramMedian time periodPopulation-based studyHistory of lymphomaHigh-risk groupLow-risk groupSimple clinical toolHistory of radiationNon-white raceHealth care providers