Beyond Statins: Novel Lipid-Lowering Agents for Reducing Risk of Atherosclerotic Cardiovascular Disease
Kayani T, Ahmad B, Chang R, Qian F, Sahinoz M, Rehan M, Giaimo A, Spatz E, Hu J. Beyond Statins: Novel Lipid-Lowering Agents for Reducing Risk of Atherosclerotic Cardiovascular Disease. Pharmacoepidemiology 2024, 3: 117-168. DOI: 10.3390/pharma3010009.Peer-Reviewed Original ResearchAtherosclerotic cardiovascular diseaseSmall interfering RNACholesteryl ester transfer proteinRandomized trialsReduced risk of atherosclerotic cardiovascular diseasePhase III randomized trialMedications due to side effectsCardiovascular diseaseNon-statin therapiesRisk of atherosclerotic cardiovascular diseaseLipid-lowering strategiesEmergence of therapiesLowering of lipid levelsOmega-3 polyunsaturated fatty acidsSmall-molecule agentsRandomized controlled trialsStatin monotherapyTarget doseOlder therapiesPharmacological loweringSide effectsControlled trialsLipid levelsCholesterol reductionLyase inhibitor