2023
Neurologic Complications of Babesiosis, United States, 2011–2021 - Volume 29, Number 6—June 2023 - Emerging Infectious Diseases journal - CDC
Locke S, O’Bryan J, Zubair A, Rethana M, Moffarah A, Krause P, Farhadian S. Neurologic Complications of Babesiosis, United States, 2011–2021 - Volume 29, Number 6—June 2023 - Emerging Infectious Diseases journal - CDC. Emerging Infectious Diseases 2023, 29: 1127-1135. PMID: 37209667, PMCID: PMC10202888, DOI: 10.3201/eid2906.221890.Peer-Reviewed Original ResearchConceptsNeurologic complicationsNeurologic symptomsRisk factorsYale-New Haven HospitalInfectious Diseases journal - CDCHigh-grade parasitemiaNeurologic risk factorsRange of symptomsAdult patientsRenal failureDiabetes mellitusFrequent symptomsHospital admissionImpaired consciousnessMedical recordsEndemic areasParasitic infectionsPatientsSymptomsIntraerythrocytic protozoaComplicationsBabesiosisNew HavenDeliriumMellitus
2022
Cardiac Complications of Human Babesiosis
Spichler-Moffarah A, Ong E, O’Bryan J, Krause PJ. Cardiac Complications of Human Babesiosis. Clinical Infectious Diseases 2022, 76: e1385-e1391. PMID: 35983604, PMCID: PMC10169432, DOI: 10.1093/cid/ciac525.Peer-Reviewed Original ResearchConceptsYale-New Haven HospitalCardiac complicationsRisk factorsIntensive care unit stayCardiovascular disease risk factorsHuman babesiosisCommon cardiac complicationHigh-grade parasitemiaLife-threatening complicationsDisease risk factorsLonger median lengthQT interval prolongationHigh mortality rateUnit stayComplication groupTick-borne diseaseAdult patientsCardiac outcomesMost patientsThin blood smearsHeart failureInterval prolongationModerate illnessRecord reviewAtrial fibrillation
2021
A new positive SARS-CoV-2 test months after severe COVID-19 illness: reinfection or intermittent viral shedding?
Tuan J, Spichler-Moffarah A, Ogbuagu O. A new positive SARS-CoV-2 test months after severe COVID-19 illness: reinfection or intermittent viral shedding? BMJ Case Reports 2021, 14: e240531. PMID: 33542020, PMCID: PMC8098910, DOI: 10.1136/bcr-2020-240531.Peer-Reviewed Case Reports and Technical NotesConceptsSARS-CoV-2 RNA testSevere acute respiratory syndrome coronavirus 2Acute respiratory syndrome coronavirus 2SARS-CoV-2 reinfectionSevere COVID-19 illnessRespiratory syndrome coronavirus 2COVID-19 reinfectionLong asymptomatic periodCOVID-19 illnessSyndrome coronavirus 2Intermittent viral sheddingAsymptomatic periodViral sheddingRNA testCoronavirus 2Clinical managementPersistent infectionDisease 4Molecular testingReinfectionRNA PCRCurrent presentationPotential casesMonthsPatients
2011
Outpatient follow-up of patients hospitalized for acute leptospirosis
Spichler A, Athanazio D, Seguro AC, Vinetz JM. Outpatient follow-up of patients hospitalized for acute leptospirosis. International Journal Of Infectious Diseases 2011, 15: e486-e490. PMID: 21616696, PMCID: PMC3117907, DOI: 10.1016/j.ijid.2011.03.020.Peer-Reviewed Original ResearchConceptsAcute leptospirosisHospital dischargeLate complicationsOutcome of leptospirosisChronic sequelaeProspective studyGeneral malaiseOutpatient settingPossible sequelaeAcute diseaseChronic diseasesMild casesSubjective complaintsFirst visitSame patientPatientsSecond visitPanic disorderObjective evidenceLeptospirosisStudy periodVisitsComplicationsSequelaeDisease
2008
Predictors of lethality in severe leptospirosis in urban Brazil.
Spichler AS, Vilaça PJ, Athanazio DA, Albuquerque JO, Buzzar M, Castro B, Seguro A, Vinetz JM. Predictors of lethality in severe leptospirosis in urban Brazil. American Journal Of Tropical Medicine And Hygiene 2008, 79: 911-4. PMID: 19052303, PMCID: PMC2640419, DOI: 10.4269/ajtmh.2008.79.911.Peer-Reviewed Original ResearchConceptsSevere leptospirosisRetrospective case-control studyPopulation-based surveillance dataDevelopment of oliguriaPredictors of deathStrong risk factorCase-control studyPredictors of lethalityDeath certificate reportingLung involvementPulmonary involvementPrognostic factorsSerologic findingsFatal outcomePatient hospitalizationRisk factorsSurvivor casesOdds ratioLethal casesHigh titersLeptospirosis casesSurveillance dataLeptospira interrogansLeptospirosisHospitalization