Mapping and characterizing N6-methyladenine in eukaryotic genomes using single-molecule real-time sequencing
Zhu S, Beaulaurier J, Deikus G, Wu TP, Strahl M, Hao Z, Luo G, Gregory JA, Chess A, He C, Xiao A, Sebra R, Schadt EE, Fang G. Mapping and characterizing N6-methyladenine in eukaryotic genomes using single-molecule real-time sequencing. Genome Research 2018, 28: 1067-1078. PMID: 29764913, PMCID: PMC6028124, DOI: 10.1101/gr.231068.117.Peer-Reviewed Original ResearchConceptsSingle-molecule real-time sequencingEukaryotic genomesReal-time sequencingDAS eventsN6-methyladenineHuman lymphoblastoid cellsGenome-wide mapsSingle-nucleotide resolutionSingle-molecule resolutionLINE-1 elementsFull-length LINE-1 elementsGreen algaeProkaryotic genomesGenomeHigh-resolution mappingSequencing dataLymphoblastoid cellsSequencingEukaryotesProkaryotesMethylomeNovel formAlgaePromoterJoint analysis