2024
Propofol vs etomidate for induction prior to invasive mechanical ventilation in patients with acute myocardial infarction
Thomas A, Banna S, Shahu A, Ali T, Schenck C, Patel B, Notarianni A, Phommalinh M, Kochar A, Heck C, van Diepen S, Miller P. Propofol vs etomidate for induction prior to invasive mechanical ventilation in patients with acute myocardial infarction. American Heart Journal 2024, 272: 116-125. PMID: 38554762, DOI: 10.1016/j.ahj.2024.03.013.Peer-Reviewed Original ResearchConceptsAssociated with lower mortalityAcute myocardial infarctionInvasive mechanical ventilationLower mortalityUS national databaseClinical Data BaseMyocardial infarctionIll patient populationLength of stayCritically ill patient populationIn-hospital mortalityInverse probability treatmentOptimal induction agentInduction agentNational databaseClinical outcomesMechanical ventilationProbability treatmentPropensity weightingPatient populationRandomized trialsMortalityUtilization of propofolVentilator daysPropofol group
2022
Staffing models in the cardiac intensive care unit
Quien M, Thomas A, Ludmir J, Miller PE. Staffing models in the cardiac intensive care unit. Current Opinion In Critical Care 2022, 28: 453-459. PMID: 35757936, DOI: 10.1097/mcc.0000000000000958.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsCritical CareCritical IllnessHospital MortalityHumansIntensive Care UnitsRetrospective StudiesUnited StatesWorkforceConceptsCardiac intensive care unitIntensive care unitCare unitContemporary cardiac intensive care unitsModern cardiac intensive care unitMechanical circulatory supportSick patient populationFuture multicenter studiesStaffing modelsPreponderance of dataShock teamRespiratory failureIll patientsCirculatory supportMulticenter studyCardiac arrestPatient populationCardiac intensivistsIll populationMortalityRecent evidenceIntensivistsPatientsRecent dataPopulation
2021
Electronic health record risk score provides earlier prognostication of clinical outcomes in patients admitted to the cardiac intensive care unit
Kunitomo Y, Thomas A, Chouairi F, Canavan ME, Kochar A, Khera R, Katz JN, Murphy C, Jentzer J, Ahmad T, Desai NR, Brennan J, Miller PE. Electronic health record risk score provides earlier prognostication of clinical outcomes in patients admitted to the cardiac intensive care unit. American Heart Journal 2021, 238: 85-88. PMID: 33891906, DOI: 10.1016/j.ahj.2021.04.004.Peer-Reviewed Original ResearchConceptsCardiac intensive care unitIntensive care unitRothman IndexCare unitRisk scoreModern cardiac intensive care unitSequential Organ Failure Assessment scoreOrgan Failure Assessment scoreElectronic health recordsCICU mortalityCICU patientsSOFA scoreCICU admissionClinical outcomesEarly prognosticationObservational studyPrognostic abilityAssessment scoresOutcome predictionHealth recordsGood calibrationSuperior discriminationPatientsAdmissionScoresTransition From an Open to Closed Staffing Model in the Cardiac Intensive Care Unit Improves Clinical Outcomes
Miller PE, Chouairi F, Thomas A, Kunitomo Y, Aslam F, Canavan ME, Murphy C, Daggula K, Metkus T, Vallabhajosyula S, Carnicelli A, Katz JN, Desai NR, Ahmad T, Velazquez EJ, Brennan J. Transition From an Open to Closed Staffing Model in the Cardiac Intensive Care Unit Improves Clinical Outcomes. Journal Of The American Heart Association 2021, 10: e018182. PMID: 33412899, PMCID: PMC7955420, DOI: 10.1161/jaha.120.018182.Peer-Reviewed Original ResearchConceptsCardiac intensive care unitIntensive care unitHospital mortalityCare unitCICU mortalityClinical outcomesModern cardiac intensive care unitSurgical intensive care unitTotal hospital chargesSeverity of illnessMultivariable logistic regressionCICU lengthMultivariable adjustmentRespiratory insufficiencyPrimary outcomeUnique admissionsHospital chargesCardiac arrestSubgroup analysisImproved outcomesMortalityLogistic regressionAdmissionClosed unitStaffing models
2020
Prevalence of Noncardiac Multimorbidity in Patients Admitted to Two Cardiac Intensive Care Units and Their Association with Mortality
Miller PE, Thomas A, Breen TJ, Chouairi F, Kunitomo Y, Aslam F, Damluji AA, Anavekar NS, Murphy JG, van Diepen S, Barsness GW, Brennan J, Jentzer J. Prevalence of Noncardiac Multimorbidity in Patients Admitted to Two Cardiac Intensive Care Units and Their Association with Mortality. The American Journal Of Medicine 2020, 134: 653-661.e5. PMID: 33129785, PMCID: PMC8079541, DOI: 10.1016/j.amjmed.2020.09.035.Peer-Reviewed Original ResearchConceptsCritical care therapiesNoncardiac comorbiditiesCICU populationCare therapyLong-term adverse clinical outcomesCardiac intensive care unitIntensive care unit practiceBetter care pathwaysIncreased hospital mortalityNoncardiac organ failureUnique patient admissionsAdverse clinical outcomesIntensive care unitMultivariable logistic regressionLength of stayAcute cardiac illnessCICU patientsHospital mortalityNoncardiac indicationsICU admissionMultivariable adjustmentOrgan failureCare unitClinical outcomesCardiac illness