Does Dexmedetomidine Ameliorate Postoperative Cognitive Dysfunction? A Brief Review of the Recent Literature
Carr ZJ, Cios TJ, Potter KF, Swick JT. Does Dexmedetomidine Ameliorate Postoperative Cognitive Dysfunction? A Brief Review of the Recent Literature. Current Neurology And Neuroscience Reports 2018, 18: 64. PMID: 30083844, DOI: 10.1007/s11910-018-0873-z.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsUse of dexmedetomidinePostoperative deliriumCognitive dysfunctionAcute postoperative deliriumPostoperative cognitive dysfunctionAlpha-2 agonistsIncidence of POCDAnti-inflammatory propertiesHigh patient mortalityHospital lengthElderly patientsHeart failurePostsurgical patientsPatient mortalityImmunomodulatory effectsVascular diseaseBrain injuryFavorable outcomeClinical studiesDexmedetomidineHigh prevalenceHuman trialsClinical investigationRecent FindingsThereAnimal models