A statistical model for functional mapping of quantitative trait loci regulating drug response
Gong Y, Wang Z, Liu T, Zhao W, Zhu Y, Johnson J, Wu R. A statistical model for functional mapping of quantitative trait loci regulating drug response. The Pharmacogenomics Journal 2004, 4: 315-321. PMID: 15263889, DOI: 10.1038/sj.tpj.6500262.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsChromosome MappingGene FrequencyModels, StatisticalPharmaceutical PreparationsQuantitative Trait LociConceptsQuantitative trait lociComplex traitsGenetic mappingTrait lociDifferent QTL genotypesPopulation genetic parametersFunction-valued traitsDrug responseMultiple genesSpecific genesHigh-resolution mappingRecombination eventsQTL genotypesDisequilibrium mappingPolymorphic markersGenetic parametersFunctional mappingTraitsGenesLociPharmacogenomics researchEnvironmental influencesPowerful toolHistoric times