2004
P.1.028 Persistent reduction in brain 5-HT1A receptorbinding in recovered depressed men using positron emission tomography and [11C]WAY-100835
Bhagwagar Z, Rabiner E, Sargente R, Grasby P, Cowen P. P.1.028 Persistent reduction in brain 5-HT1A receptorbinding in recovered depressed men using positron emission tomography and [11C]WAY-100835. European Neuropsychopharmacology 2004, 14: s185. DOI: 10.1016/s0924-977x(04)80117-2.Peer-Reviewed Original Research
2001
PET measurement of the influence of corticosteroids on serotonin-1A receptor number
Montgomery A, Bench C, Young A, Hammers A, Gunn R, Bhagwagar Z, Grasby P. PET measurement of the influence of corticosteroids on serotonin-1A receptor number. Biological Psychiatry 2001, 50: 668-676. PMID: 11704073, DOI: 10.1016/s0006-3223(01)01205-7.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnti-Inflammatory AgentsBinding, CompetitiveDose-Response Relationship, DrugDouble-Blind MethodDrug Administration ScheduleFemaleHippocampusHumansHydrocortisoneHypothalamo-Hypophyseal SystemMaleMiddle AgedPituitary-Adrenal SystemReceptors, SerotoninReceptors, Serotonin, 5-HT1Tomography, Emission-ComputedConceptsPositron emission tomographyReceptor numberReceptor bindingPlacebo-controlled designInfluence of corticosteroidsSingle doseSerotonergic systemPreclinical studiesCorticosteroidsNormal subjectsModulatory effectsAlters 5Corticosteroid levelsBrain regionsEmission tomographyElevated levelsPET measurementsHippocampusHuman brainPatientsHydrocortisoneDoseBrainReceptors