2018
Novel Eye Plaque Designs for Brachytherapy of Iris and Ciliary Body Melanoma and the First Clinical Application
Liu W, Kim JM, Young BK, Nath R, Chen Z, Decker RH, Astrahan MA, Pointdujour-Lim R. Novel Eye Plaque Designs for Brachytherapy of Iris and Ciliary Body Melanoma and the First Clinical Application. Ocular Oncology And Pathology 2018, 5: 220-228. PMID: 31049331, PMCID: PMC6489066, DOI: 10.1159/000493269.Peer-Reviewed Original ResearchIris melanomaCiliary bodyFirst clinical applicationPlaque designPoor patient tolerabilityCiliary body melanomaClinical applicationEye plaque brachytherapyPatient tolerabilityAdverse eventsCorneal edemaPlaque brachytherapyTumor apexTumor baseClinical casesMelanomaPatientsPlaquesSurgical maneuverabilityPlaque modelEffective dose distributionTreatment planningTolerabilityTreatmentImage-based treatment planning
2017
Local DNA Repair Inhibition for Sustained Radiosensitization of High-Grade Gliomas
King AR, Corso CD, Chen EM, Song E, Bongiorni P, Chen Z, Sundaram RK, Bindra RS, Saltzman WM. Local DNA Repair Inhibition for Sustained Radiosensitization of High-Grade Gliomas. Molecular Cancer Therapeutics 2017, 16: 1456-1469. PMID: 28566437, PMCID: PMC5545124, DOI: 10.1158/1535-7163.mct-16-0788.Peer-Reviewed Original ResearchConceptsHigh-grade gliomasPoor blood-brain barrier penetrationLocal disease progressionBlood-brain barrier penetrationEffect of radiotherapyIntrinsic pontine gliomaTreatment of glioblastomaMol Cancer TherCranial radiationDosing schedulesMultimodal treatmentIntracranial gliomasDisease progressionExtracranial tumorsPontine gliomaAggressive phenotypeRadiotherapy approachesGliomasMinimal toxicityRadiotherapyGlioblastomaBarrier penetrationTreatmentRadiosensitizerChemotherapy