2010
Intraflagellar Transport Proteins Are Essential for Cilia Formation and for Planar Cell Polarity
Cao Y, Park A, Sun Z. Intraflagellar Transport Proteins Are Essential for Cilia Formation and for Planar Cell Polarity. Journal Of The American Society Of Nephrology 2010, 21: 1326-1333. PMID: 20576807, PMCID: PMC2938599, DOI: 10.1681/asn.2009091001.Peer-Reviewed Original ResearchMeSH KeywordsAdaptor Proteins, Signal TransducingAnimalsCell PolarityCiliaMutationZebrafishZebrafish ProteinsConceptsPlanar cell polarityIntraflagellar transport proteinsCell polarityCilia formationIFT mutantsIFT proteinsDefective planar cell polarityTransport proteinsCore PCP componentsKidney cyst formationConserved roleEarly developmental stagesCiliary assemblyIFT genesPCP componentsCilia formMulticiliated cellsPronephric ductGene productsMaternal contributionBasal bodiesMultiple organismsDevelopmental stagesMaternal depositionProtein
2008
Cystic Kidney Gene seahorse Regulates Cilia-Mediated Processes and Wnt Pathways
Kishimoto N, Cao Y, Park A, Sun Z. Cystic Kidney Gene seahorse Regulates Cilia-Mediated Processes and Wnt Pathways. Developmental Cell 2008, 14: 954-961. PMID: 18539122, DOI: 10.1016/j.devcel.2008.03.010.Peer-Reviewed Original ResearchConceptsWnt pathwayCiliary signalsImportant sensory organelleKidney cyst formationNoncanonical Wnt pathwayCanonical Wnt pathwayLeft-right asymmetryCilia assemblySensory organellesCiliated tissuesCellular eventsCell typesSeahorsesCiliary functionPathwayCiliaCyst formationDishevelledInversinGastrulationVertebratesOrganellesTranscriptsProteinCascade