Structural proteomics of an archaeon
Christendat D, Yee A, Dharamsi A, Kluger Y, Savchenko A, Cort J, Booth V, Mackereth C, Saridakis V, Ekiel I, Kozlov G, Maxwell K, Wu N, McIntosh L, Gehring K, Kennedy M, Davidson A, Pai E, Gerstein M, Edwards A, Arrowsmith C. Structural proteomics of an archaeon. Nature Structural & Molecular Biology 2000, 7: 903-909. PMID: 11017201, DOI: 10.1038/82823.Peer-Reviewed Original ResearchConceptsStructural proteomicsHigh-throughput strategyFunctional genomicsNonmembrane proteinsPutative functionsBiochemical functionsSequence analysisMethanobacterium thermoautotrophicumProtein propertiesThroughput strategyX-ray crystallographicBiochemical methodsProteomicsStructural studiesCentral roleProteinStructural targetsNMR spectroscopic analysisProteomeArchaeonGenomicsThermoautotrophicumSequenceFunctionSpectroscopic analysis