2007
Arabidopsis POT1 associates with the telomerase RNP and is required for telomere maintenance
Surovtseva Y, Shakirov E, Vespa L, Osbun N, Song X, Shippen D. Arabidopsis POT1 associates with the telomerase RNP and is required for telomere maintenance. The EMBO Journal 2007, 26: 3653-3661. PMID: 17627276, PMCID: PMC1949013, DOI: 10.1038/sj.emboj.7601792.Peer-Reviewed Original ResearchConceptsTelomere length regulationLength regulationChromosome end protectionSingle-copy geneNovel accessory factorTelomerase RNPTelomere proteinsTelomere maintenanceSequence similarityTelomeric DNAAccessory factorsEnd protectionTelomerase enzymeGenetic analysisSame pathwayUnsynchronized cellsS phaseRapid evolutionTelomerase activityTelomeraseTelomeresGenesProteinRegulationPOT1
2005
The Arabidopsis Pot1 and Pot2 Proteins Function in Telomere Length Homeostasis and Chromosome End Protection
Shakirov E, Surovtseva Y, Osbun N, Shippen D. The Arabidopsis Pot1 and Pot2 Proteins Function in Telomere Length Homeostasis and Chromosome End Protection. Molecular And Cellular Biology 2005, 25: 7725-7733. PMID: 16107718, PMCID: PMC1190295, DOI: 10.1128/mcb.25.17.7725-7733.2005.Peer-Reviewed Original ResearchConceptsChromosome end protectionTelomere length homeostasisEnd protectionLength homeostasisGenome instabilityWild typePot1-like proteinsSevere growth defectOligonucleotide/oligosaccharideMassive genome instabilityBulk telomeresTransgenic plantsGrowth defectProtein functionPositive regulationN-terminusBinding proteinAnalogous regionMutantsArabidopsisPlantsLength controlCorresponding regionPOT1Protein