2023
Force redistribution in clathrin-mediated endocytosis revealed by coiled-coil force sensors
Ren Y, Yang J, Fujita B, Jin H, Zhang Y, Berro J. Force redistribution in clathrin-mediated endocytosis revealed by coiled-coil force sensors. Science Advances 2023, 9: eadi1535. PMID: 37831774, PMCID: PMC10575576, DOI: 10.1126/sciadv.adi1535.Peer-Reviewed Original ResearchConceptsActin cytoskeletonPlasma membraneHuntingtin Interacting Protein 1Clathrin-mediated endocytosisCountless cellular processesEndocytic machineryCellular processesClathrin latticesProtein condensationCytoskeletonEnd4pProtein 1Membrane deformationPiconewton forcesEndocytosisVivo force measurementsMembranePiconewtonsClathrinMachineryProteinCoatMolecular scale
2021
Rapid adaptation of endocytosis, exocytosis and eisosomes after an acute increase in membrane tension in yeast cells
Lemière J, Ren Y, Berro J. Rapid adaptation of endocytosis, exocytosis and eisosomes after an acute increase in membrane tension in yeast cells. ELife 2021, 10: e62084. PMID: 33983119, PMCID: PMC9045820, DOI: 10.7554/elife.62084.Peer-Reviewed Original ResearchConceptsClathrin-mediated endocytosisMembrane tensionActin machineryYeast cellsFission yeast cellsRate of endocytosisRate of exocytosisActin assemblyLarge membrane tensionPlasma membraneCell wallMolecular mechanismsTurgor pressureEndocytosisRapid adaptationEisosomesExocytosisMachineryQuantitative microscopyMinute time scaleHypotonic shockCellsEukaryotesMembraneTension regulation
2016
Increase in Growth Cone Size Correlates with Decrease in Neurite Growth Rate
Ren Y, Suter D. Increase in Growth Cone Size Correlates with Decrease in Neurite Growth Rate. Neural Plasticity 2016, 2016: 3497901. PMID: 27274874, PMCID: PMC4870373, DOI: 10.1155/2016/3497901.Peer-Reviewed Original Research
2015
Src and cortactin promote lamellipodia protrusion and filopodia formation and stability in growth cones
He Y, Ren Y, Wu B, Decourt B, Lee A, Taylor A, Suter D. Src and cortactin promote lamellipodia protrusion and filopodia formation and stability in growth cones. Molecular Biology Of The Cell 2015, 26: 3229-3244. PMID: 26224308, PMCID: PMC4569314, DOI: 10.1091/mbc.e15-03-0142.Peer-Reviewed Original ResearchConceptsActin network densityGrowth conesSrc tyrosine kinaseFluorescent speckle microscopyState of actinNeuronal growth conesGrowth cone motilityLamellipodia protrusionActin organizationActin assemblyFilopodia formationActin bundlesAplysia growth conesSpeckle microscopyTyrosine kinaseUnderlying cellular mechanismsFilopodial densityCone motilityCellular mechanismsSrcFilopodiaActivation stateLamellipodiaSRC2Axonal growth