2014
Common intermediates and kinetics, but different energetics, in the assembly of SNARE proteins
Zorman S, Rebane AA, Ma L, Yang G, Molski MA, Coleman J, Pincet F, Rothman JE, Zhang Y. Common intermediates and kinetics, but different energetics, in the assembly of SNARE proteins. ELife 2014, 3: e03348. PMID: 25180101, PMCID: PMC4166003, DOI: 10.7554/elife.03348.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsEnergy TransferHumansKineticsModels, MolecularMolecular Sequence DataMultiprotein ComplexesOptical TweezersProtein FoldingProtein Structure, QuaternaryProtein Structure, SecondaryQa-SNARE ProteinsRatsSequence Homology, Amino AcidSNARE ProteinsThermodynamicsVesicle-Associated Membrane Protein 2Vesicular Transport ProteinsConceptsSoluble N-ethylmaleimide-sensitive factor attachment protein receptorsSNARE complexN-ethylmaleimide-sensitive factor attachment protein receptorsMembrane fusionFactor attachment protein receptorsAttachment protein receptorsHigh-resolution optical tweezersNeuronal SNARE complexFolding/assemblyEnergy releaseSNARE proteinsSingle-molecule levelProtein receptorsDomain associationOptical tweezersTerminal partZippering mechanismFusion kineticsZipperingComplexesAssemblyDifferent energeticsEnergyYeastTweezers
2003
Statistical Mechanics of Sequence-Dependent Circular DNA and Its Application For DNA Cyclization
Zhang Y, Crothers DM. Statistical Mechanics of Sequence-Dependent Circular DNA and Its Application For DNA Cyclization. Biophysical Journal 2003, 84: 136-153. PMID: 12524271, PMCID: PMC1302599, DOI: 10.1016/s0006-3495(03)74838-3.Peer-Reviewed Original ResearchConceptsStatistical mechanicsAccurate analytic expressionsInhomogeneous DNAMonte Carlo simulationsAnalytic expressionsPartition functionHarmonic approximationEffect of curvatureCarlo simulationsEquilibrium configurationsLinear formThermal fluctuationsThermodynamic quantitiesSequence-dependent DNA bendingDNA cyclizationMinimum energy configurationIterative searchNew theoryMechanicsJ factorEnergy configurationTheoryCurvatureSimulationsApproximation