2015
Munc18-1-regulated stage-wise SNARE assembly underlying synaptic exocytosis
Ma L, Rebane AA, Yang G, Xi Z, Kang Y, Gao Y, Zhang Y. Munc18-1-regulated stage-wise SNARE assembly underlying synaptic exocytosis. ELife 2015, 4: e09580. PMID: 26701912, PMCID: PMC4744192, DOI: 10.7554/elife.09580.Peer-Reviewed Original ResearchConceptsN-terminal regulatory domainSNARE assemblyMunc18-1Folding/assemblySNARE domainVesicle dockingDifferent assembly stagesRegulatory domainLinker domainSynaptic exocytosisDistinct functionsRapid exocytosisC-terminalN-terminalExocytosisAttachment receptorAssemblyDistinct stagesSyntaxinDomainMutationsFusionOptical tweezersAssembly stageDocking
2012
Single-molecule observation of helix staggering, sliding, and coiled coil misfolding
Xi Z, Gao Y, Sirinakis G, Guo H, Zhang Y. Single-molecule observation of helix staggering, sliding, and coiled coil misfolding. Proceedings Of The National Academy Of Sciences Of The United States Of America 2012, 109: 5711-5716. PMID: 22451899, PMCID: PMC3326506, DOI: 10.1073/pnas.1116784109.Peer-Reviewed Original Research