Statistical Mechanics of Sequence-Dependent Circular DNA and Its Application For DNA Cyclization
Zhang Y, Crothers DM. Statistical Mechanics of Sequence-Dependent Circular DNA and Its Application For DNA Cyclization. Biophysical Journal 2003, 84: 136-153. PMID: 12524271, PMCID: PMC1302599, DOI: 10.1016/s0006-3495(03)74838-3.Peer-Reviewed Original ResearchConceptsStatistical mechanicsAccurate analytic expressionsInhomogeneous DNAMonte Carlo simulationsAnalytic expressionsPartition functionHarmonic approximationEffect of curvatureCarlo simulationsEquilibrium configurationsLinear formThermal fluctuationsThermodynamic quantitiesSequence-dependent DNA bendingDNA cyclizationMinimum energy configurationIterative searchNew theoryMechanicsJ factorEnergy configurationTheoryCurvatureSimulationsApproximation