Functional Cardiomyocytes Derived from Isl1 Cardiac Progenitors via Bmp4 Stimulation
Cagavi E, Bartulos O, Suh CY, Sun B, Yue Z, Jiang Z, Yue L, Qyang Y. Functional Cardiomyocytes Derived from Isl1 Cardiac Progenitors via Bmp4 Stimulation. PLOS ONE 2014, 9: e110752. PMID: 25522363, PMCID: PMC4270687, DOI: 10.1371/journal.pone.0110752.Peer-Reviewed Original ResearchConceptsCardiac progenitor cellsCardiac repairProliferative abilityProgenitor cellsCell-based cardiac regenerative therapySignificant therapeutic valueCardiac regenerative therapyAdult cardiac progenitor cellsStem cellsCPC culturesHigh proliferative abilityHeart failureCardiac originCardiac differentiationMyocardial infarctionAnterior heart fieldInduction of Bmp4Leading causePotential treatmentRole of BMP4Therapeutic valueCardiac progenitorsUntreated cardiomyocytesProtein expressionRegenerative therapyAdvancements in Induced Pluripotent Stem Cell Technology for Cardiac Regenerative Medicine
Suh CY, Wang Z, Bártulos O, Qyang Y. Advancements in Induced Pluripotent Stem Cell Technology for Cardiac Regenerative Medicine. Journal Of Cardiovascular Pharmacology And Therapeutics 2014, 19: 330-339. PMID: 24651517, PMCID: PMC4169350, DOI: 10.1177/1074248414523676.Peer-Reviewed Original ResearchCardiovascular diseaseCause of morbidityCardiac cellsCardiac regenerative medicineCardiac regenerative therapyPromising cell sourcePluripotent stem cell (iPSC) technologyDiseaseRegenerative therapyInduced pluripotent stem cell (iPSC) technologyCellular typesCell sourceTherapyStem cellsStem cell technologyPluripotent stem cellsRegenerative medicine