Balance of the Sexes: Addressing Sex Differences in Preclinical Research.
Zakiniaeiz Y, Cosgrove KP, Potenza MN, Mazure CM. Balance of the Sexes: Addressing Sex Differences in Preclinical Research. The Yale Journal Of Biology And Medicine 2016, 89: 255-9. PMID: 27354851, PMCID: PMC4918870.Peer-Reviewed Original ResearchSex differences in amphetamine-induced dopamine release in the dorsolateral prefrontal cortex of tobacco smokers
Zakiniaeiz Y, Hillmer AT, Matuskey D, Nabulsi N, Ropchan J, Mazure CM, Picciotto MR, Huang Y, McKee SA, Morris ED, Cosgrove KP. Sex differences in amphetamine-induced dopamine release in the dorsolateral prefrontal cortex of tobacco smokers. Neuropsychopharmacology 2019, 44: 2205-2211. PMID: 31269510, PMCID: PMC6897943, DOI: 10.1038/s41386-019-0456-y.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsMeSH KeywordsAdultAmphetamineDopamineFemaleHumansMalePositron-Emission TomographyPrefrontal CortexReceptors, Dopamine D2Sex CharacteristicsSmokersConceptsDA releasePositron emission tomographyD2R availabilityDorsolateral prefrontal cortexMale smokersFemale smokersTobacco smokingPrefrontal cortexAmphetamine-induced DA releaseAmphetamine-induced dopamine releaseCortical DA releaseMesocortical DA systemEffects of nicotineSmoking-related behaviorsMesolimbic dopamine systemLong-term abstinenceSex differencesGender-specific treatmentFemale nonsmokersTobacco smokersAmphetamine administrationDopamine releaseNeurochemical mechanismsNonsmokersSmokersSex Differences across Retrospective Transitions in Posttraumatic Stress and Substance Use Disorders
Peltier MR, Roberts W, Verplaetse TL, Zakiniaeiz Y, Burke C, Moore KE, McKee SA. Sex Differences across Retrospective Transitions in Posttraumatic Stress and Substance Use Disorders. Journal Of Dual Diagnosis 2021, 18: 11-20. PMID: 34965199, PMCID: PMC9086923, DOI: 10.1080/15504263.2021.2016027.Peer-Reviewed Original ResearchMeSH KeywordsComorbidityFemaleHumansMaleRetrospective StudiesSex CharacteristicsStress Disorders, Post-TraumaticSubstance-Related DisordersConceptsDrug use disordersOngoing posttraumatic stress disorderSubstance use disordersSUD/PTSDPosttraumatic stress disorderNew PTSD diagnosisImpact of sexUse disordersDiagnosis of SUDPast-year substance use disorderPTSD diagnosisConcurrent substance use disordersDiagnosis of PTSDPoor treatment outcomesNational Epidemiologic SurveyBidirectional relationshipSex-specific analysesPotential sex-specific differencesTreatment outcomesDiagnostic group differences and exploratory sex differences in intrinsic connectivity during fMRI Stroop in individuals with and without cocaine use disorder
Zakiniaeiz Y, Lacadie C, Macdonald-Gagnon G, DeVito E, Potenza M. Diagnostic group differences and exploratory sex differences in intrinsic connectivity during fMRI Stroop in individuals with and without cocaine use disorder. Drug And Alcohol Dependence 2023, 251: 110962. PMID: 37716288, PMCID: PMC10557108, DOI: 10.1016/j.drugalcdep.2023.110962.Peer-Reviewed Original ResearchMeSH KeywordsBrainBrain MappingCocaineFemaleHumansMagnetic Resonance ImagingMaleSex CharacteristicsStroop TestSubstance-Related DisordersConceptsCocaine use disorderCognitive controlStroop performanceIntrinsic connectivityStroop task performanceFMRI Stroop taskDiagnostic groupsUse disordersDiagnostic group differencesMain effectHealthy comparison subjectsStroop effectStroop taskBehavioral resultsTask performanceFrontal gyrusIntrinsic connectivity distributionPrefrontal cortexAuditory areasGroup differencesBrain connectivityCingulate gyrusStroopBehavioral differencesHC group