Featured Publications
Mechanisms and Clinical Features of Co-Occurring Opioid and Nicotine Use
Lichenstein SD, Zakiniaeiz Y, Yip SW, Garrison KA. Mechanisms and Clinical Features of Co-Occurring Opioid and Nicotine Use. Current Addiction Reports 2019, 6: 114-125. PMID: 32864292, PMCID: PMC7451029, DOI: 10.1007/s40429-019-00245-3.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsNicotine useClinical featuresCholinergic systemUse disordersOpioid use disorderPurpose of ReviewToSubstance use disordersSex/gender considerationsRecent FindingsOpioidPathophysiological mechanismsSmoking cessationRisk factorsTreatment outcomesDrug rewardOpioidsFurther studiesHigh rateTreatmentDisordersHighlight areasPainReviewToEtiologyPharmacologicalCessationThe role of neurosteroids in posttraumatic stress disorder and alcohol use disorder: A review of 10 years of clinical literature and treatment implications
Peltier M, Verplaetse T, Altemus M, Zakiniaeiz Y, Ralevski E, Mineur Y, Gueorguieva R, Picciotto M, Cosgrove K, Petrakis I, McKee S. The role of neurosteroids in posttraumatic stress disorder and alcohol use disorder: A review of 10 years of clinical literature and treatment implications. Frontiers In Neuroendocrinology 2024, 73: 101119. PMID: 38184208, PMCID: PMC11185997, DOI: 10.1016/j.yfrne.2023.101119.Peer-Reviewed Original ResearchPosttraumatic stress disorderAlcohol use disorderStress disorderContext of PTSDPTSD/AUDConcurrent posttraumatic stress disorderUnderlying neurobiological mechanismsUse disordersAlcohol-related variablesNeurobiological mechanismsPTSD diagnosisTreatment developmentTreatment implicationsBody of literatureNovel interventionsClinical literatureRole of neurosteroidsDisordersTreatment outcomesYears of researchAlcohol consumptionExogenous pregnenolonePharmacological treatmentBiological variablesAllopregnanolone
2021
Neurobiology of Addiction
Gogliettino A, Potenza M, Yip S, Zakiniaeiz Y, Zhai Z. Neurobiology of Addiction. DeckerMed Medical Cannabis 2021 DOI: 10.2310/cannabis.13044.ChaptersFunctional magnetic resonance imagingBrain functionCo-occurring disordersCognitive aspectsGambling disorderBehavioral addictionsCognitive functionAddictive disordersSubstance addictionDSM-5Substance useNegative consequencesNeurochemical systemsNegative healthVisual representationAddictionSocial consequencesExtant literatureNeurobiologyDisordersCurrent treatment strategiesQuality of lifeMagnetic resonance imagingPositron emission tomographyGamblingNeurobiology of Addiction
Gogliettino A, Potenza M, Yip S, Zakiniaeiz Y, Zhai Z. Neurobiology of Addiction. DeckerMed Psychiatry 2021 DOI: 10.2310/psych.13044.ChaptersFunctional magnetic resonance imagingBrain functionCo-occurring disordersCognitive aspectsGambling disorderBehavioral addictionsCognitive functionAddictive disordersSubstance addictionDSM-5Substance useNegative consequencesNeurochemical systemsNegative healthVisual representationAddictionSocial consequencesExtant literatureNeurobiologyDisordersCurrent treatment strategiesQuality of lifeMagnetic resonance imagingPositron emission tomographyGambling
2020
Chapter 9 Sex and the dopaminergic system: Insights from addiction studies
Woodcock EA, Zakiniaeiz Y, Morris ED, Cosgrove KP. Chapter 9 Sex and the dopaminergic system: Insights from addiction studies. Handbook Of Clinical Neurology 2020, 175: 141-165. PMID: 33008522, PMCID: PMC11267480, DOI: 10.1016/b978-0-444-64123-6.00011-4.Peer-Reviewed Original ResearchConceptsDopaminergic systemSex differencesSubstance use disordersDopamine neurobiologyTobacco smokingSex hormonesPsychiatric disordersUse disordersDopamine functionClinical disparitiesCognitive functionDisordersAddiction researchAddiction studiesNeurobiologySmokingDifferencesGenetic underpinningsHormone