2021
The effect of calorie intake, fasting, and dietary composition on metabolic health and gut microbiota in mice
Zhang Z, Chen X, Loh Y, Yang X, Zhang C. The effect of calorie intake, fasting, and dietary composition on metabolic health and gut microbiota in mice. BMC Biology 2021, 19: 51. PMID: 33740961, PMCID: PMC7977615, DOI: 10.1186/s12915-021-00987-5.Peer-Reviewed Original ResearchConceptsHigh-fat dietAd libitum groupMetabolic healthGut microbiotaIntermittent fastingNormal chow miceTotal energy intakeGut microbiota modulationDietary structureIF regimenMetabolic ameliorationNormal chowCR regimenMicrobiota modulationFood intakeDietary regimensCalorie intakeCR groupCR miceRegimenControl groupEnergy intakeGut microbial communityLipid metabolismFasting-refeeding cycle
2019
Timing of Calorie Restriction in Mice Impacts Host Metabolic Phenotype with Correlative Changes in Gut Microbiota
Zhang L, Xue X, Zhai R, Yang X, Li H, Zhao L, Zhang C. Timing of Calorie Restriction in Mice Impacts Host Metabolic Phenotype with Correlative Changes in Gut Microbiota. MSystems 2019, 4: 10.1128/msystems.00348-19. PMID: 31796564, PMCID: PMC6890928, DOI: 10.1128/msystems.00348-19.Peer-Reviewed Original ResearchGut microbiotaCalorie restrictionMetabolic phenotypeLate-night eatingRestricted calorie intakeSystemic inflammatory markersIntestinal barrier functionCalorie-restricted miceHost metabolic phenotypeEffects of CRRestriction of foodGut microbiota structureExtended fasting periodPhysiological changesInflammatory markersNormal chowFat accumulationFood intakeCalorie intakeCR miceGlucose metabolismMuscle lossOverall healthFasting periodMice