2024
Racial and Ethnic Disparities in Age-Specific All-Cause Mortality During the COVID-19 Pandemic
Faust J, Renton B, Bongiovanni T, Chen A, Sheares K, Du C, Essien U, Fuentes-Afflick E, Haywood T, Khera R, King T, Li S, Lin Z, Lu Y, Marshall A, Ndumele C, Opara I, Loarte-Rodriguez T, Sawano M, Taparra K, Taylor H, Watson K, Yancy C, Krumholz H. Racial and Ethnic Disparities in Age-Specific All-Cause Mortality During the COVID-19 Pandemic. JAMA Network Open 2024, 7: e2438918. PMID: 39392630, DOI: 10.1001/jamanetworkopen.2024.38918.Peer-Reviewed Original ResearchConceptsCOVID-19 public health emergencyNon-HispanicPublic health emergencyOther Pacific IslanderExcess mortalityAlaska NativesUS populationExcess deathsRates of excess mortalityCross-sectional study analyzed dataYears of potential lifeMortality relative riskNon-Hispanic whitesCross-sectional studyPacific IslandersStudy analyzed dataAll-cause mortalityEthnic groupsMortality disparitiesMortality ratioTotal populationDeath certificatesEthnic disparitiesMain OutcomesDecedent ageCause-Specific Mortality Rates Among the US Black Population
Arun A, Caraballo C, Sawano M, Lu Y, Khera R, Yancy C, Krumholz H. Cause-Specific Mortality Rates Among the US Black Population. JAMA Network Open 2024, 7: e2436402. PMID: 39348122, PMCID: PMC11443349, DOI: 10.1001/jamanetworkopen.2024.36402.Peer-Reviewed Original ResearchAssociation of marital/partner status with hospital readmission among young adults with acute myocardial infarction.
Zhu C, Dreyer R, Li F, Spatz E, Caraballo C, Mahajan S, Raparelli V, Leifheit E, Lu Y, Krumholz H, Spertus J, D'Onofrio G, Pilote L, Lichtman J. Association of marital/partner status with hospital readmission among young adults with acute myocardial infarction. PLOS ONE 2024, 19: e0287949. PMID: 38277368, PMCID: PMC10817183, DOI: 10.1371/journal.pone.0287949.Peer-Reviewed Original ResearchConceptsMarital/partner statusPsychosocial factorsAcute myocardial infarctionYoung adultsHospital dischargeYear of hospital dischargeYoung acute myocardial infarctionAssociated with 1.3-foldCohort of young adultsLong-term readmissionCox proportional hazards modelsStatus interactionSimilar-aged menMyocardial infarctionProportional hazards modelUnpartnered statusPatient interviewsPhysician panelCardiovascular healthHospital readmissionSocioeconomic factorsAMI survivorsSequential adjustmentCardiac readmissionMultiple imputation
2023
Impact of Marital Stress on 1‐Year Health Outcomes Among Young Adults With Acute Myocardial Infarction
Zhu C, Dreyer R, Li F, Spatz E, Caraballo‐Cordovez C, Mahajan S, Raparelli V, Leifheit E, Lu Y, Krumholz H, Spertus J, D'Onofrio G, Pilote L, Lichtman J. Impact of Marital Stress on 1‐Year Health Outcomes Among Young Adults With Acute Myocardial Infarction. Journal Of The American Heart Association 2023, 12: e030031. PMID: 37589125, PMCID: PMC10547344, DOI: 10.1161/jaha.123.030031.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionCardiac-specific qualityGeneric health statusMyocardial infarctionBaseline healthMarital stressHealth outcomesHealth statusWorse patient-reported outcomesMental healthYoung adultsObservational cohort studyPatient-reported outcomesSocioeconomic factorsWorse mental healthReadmission 1Cause readmissionCohort studyYounger patientsRoutine screeningDepressive symptomsGreater oddsAnginaMale participantsOutcomesNonexercise machine learning models for maximal oxygen uptake prediction in national population surveys.
Liu Y, Herrin J, Huang C, Khera R, Dhingra L, Dong W, Mortazavi B, Krumholz H, Lu Y. Nonexercise machine learning models for maximal oxygen uptake prediction in national population surveys. Journal Of The American Medical Informatics Association 2023, 30: 943-952. PMID: 36905605, PMCID: PMC10114129, DOI: 10.1093/jamia/ocad035.Peer-Reviewed Original Research
2022
Sex-Specific Risk Factors Associated With First Acute Myocardial Infarction in Young Adults
Lu Y, Li SX, Liu Y, Rodriguez F, Watson KE, Dreyer RP, Khera R, Murugiah K, D’Onofrio G, Spatz ES, Nasir K, Masoudi FA, Krumholz HM. Sex-Specific Risk Factors Associated With First Acute Myocardial Infarction in Young Adults. JAMA Network Open 2022, 5: e229953. PMID: 35503221, PMCID: PMC9066284, DOI: 10.1001/jamanetworkopen.2022.9953.Peer-Reviewed Original ResearchConceptsFirst acute myocardial infarctionAcute myocardial infarctionPsychosocial risk factorsRisk factor profilePopulation attributable fractionRisk factor associationsRisk factorsOdds ratioYoung womenAMI subtypesMyocardial infarctionPrevention of AMIType 1 acute myocardial infarctionFactor profileRisk of AMITraditional cardiovascular risk factorsSex-specific risk factorsFactor associationsYoung adultsRisk factor modificationCardiovascular risk factorsStrong associationNutrition Examination SurveyCase-control studyPopulation-based controlsAnalysis of Dual Combination Therapies Used in Treatment of Hypertension in a Multinational Cohort
Lu Y, Van Zandt M, Liu Y, Li J, Wang X, Chen Y, Chen Z, Cho J, Dorajoo SR, Feng M, Hsu MH, Hsu JC, Iqbal U, Jonnagaddala J, Li YC, Liaw ST, Lim HS, Ngiam KY, Nguyen PA, Park RW, Pratt N, Reich C, Rhee SY, Sathappan SMK, Shin SJ, Tan HX, You SC, Zhang X, Krumholz HM, Suchard MA, Xu H. Analysis of Dual Combination Therapies Used in Treatment of Hypertension in a Multinational Cohort. JAMA Network Open 2022, 5: e223877. PMID: 35323951, PMCID: PMC8948532, DOI: 10.1001/jamanetworkopen.2022.3877.Peer-Reviewed Original ResearchConceptsDual combination therapyUse of ACEIAntihypertensive drug classesProportion of patientsKhoo Teck Puat HospitalCombination therapyUniversity Hospital databaseHospital databaseDrug classesDual combinationSouth Western Sydney Local Health DistrictWestern Sydney Local Health DistrictPatients age 65 yearsSydney Local Health DistrictElectronic health record databasePatients age 18Local Health DistrictAge 65 yearsTreatment of hypertensionHealth record databaseARB monotherapyTreatment escalationAdult patientsCohort studyCombination regimen
2021
Effectiveness of an impedance cardiography guided treatment strategy to improve blood pressure control in a real-world setting: results from a pragmatic clinical trial
Wang L, Lu Y, Wang H, Gu J, J Z, Lian Z, Zhang Z, Krumholz H, Sun N. Effectiveness of an impedance cardiography guided treatment strategy to improve blood pressure control in a real-world setting: results from a pragmatic clinical trial. Open Heart 2021, 8: e001719. PMID: 34580169, PMCID: PMC8477318, DOI: 10.1136/openhrt-2021-001719.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAntihypertensive AgentsBlood PressureCardiography, ImpedanceChinaClinical Decision-MakingFemaleFollow-Up StudiesHumansHypertensionIncidenceMaleMiddle AgedPractice Guidelines as TopicRetrospective StudiesTherapy, Computer-AssistedTime FactorsTreatment OutcomeYoung AdultConceptsBody mass indexPeking University People's HospitalStandard care groupBlood pressure controlSystolic BPHaemodynamic groupsTreatment strategiesImpedance cardiographyBaseline BPBP goalHypertension clinicHaemodynamic profileBP levelsCare groupPeople's HospitalMean baseline systolic BPPressure controlReal-world clinical practiceBaseline systolic BPMean systolic BPDiastolic BP levelsProportion of patientsPragmatic clinical trialsReal-world populationBaseline DBP
2017
Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults
Abarca-Gómez L, Abdeen Z, Hamid Z, Abu-Rmeileh N, Acosta-Cazares B, Acuin C, Adams R, Aekplakorn W, Afsana K, Aguilar-Salinas C, Agyemang C, Ahmadvand A, Ahrens W, Ajlouni K, Akhtaeva N, Al-Hazzaa H, Al-Othman A, Al-Raddadi R, Al Buhairan F, Al Dhukair S, Ali M, Ali O, Alkerwi A, Alvarez-Pedrerol M, Aly E, Amarapurkar D, Amouyel P, Amuzu A, Andersen L, Anderssen S, Andrade D, Ängquist L, Anjana R, Aounallah-Skhiri H, Araújo J, Ariansen I, Aris T, Arlappa N, Arveiler D, Aryal K, Aspelund T, Assah F, Assunção M, Aung M, Avdicová M, Azevedo A, Azizi F, Babu B, Bahijri S, Baker J, Balakrishna N, Bamoshmoosh M, Banach M, Bandosz P, Banegas J, Barbagallo C, Barceló A, Barkat A, Barros A, Barros M, Bata I, Batieha A, Batista R, Batyrbek A, Baur L, Beaglehole R, Romdhane H, Benedics J, Benet M, Bennett J, Bernabe-Ortiz A, Bernotiene G, Bettiol H, Bhagyalaxmi A, Bharadwaj S, Bhargava S, Bhatti Z, Bhutta Z, Bi H, Bi Y, Biehl A, Bikbov M, Bista B, Bjelica D, Bjerregaard P, Bjertness E, Bjertness M, Björkelund C, Blokstra A, Bo S, Bobak M, Boddy L, Boehm B, Boeing H, Boggia J, Boissonnet C, Bonaccio M, Bongard V, Bovet P, Braeckevelt L, Braeckman L, Bragt M, Brajkovich I, Branca F, Breckenkamp J, Breda J, Brenner H, Brewster L, Brian G, Brinduse L, Bruno G, Bueno-de-Mesquita H, Bugge A, Buoncristiano M, Burazeri G, Burns C, de León A, Cacciottolo J, Cai H, Cama T, Cameron C, Camolas J, Can G, Cândido A, Capanzana M, Capuano V, Cardoso V, Carlsson A, Carvalho M, Casanueva F, Casas J, Caserta C, Chamukuttan S, Chan A, Chan Q, Chaturvedi H, Chaturvedi N, Chen C, Chen F, Chen H, Chen S, Chen Z, Cheng C, Chetrit A, Chikova-Iscener E, Chiolero A, Chiou S, Chirita-Emandi A, Chirlaque M, Cho B, Cho Y, Christensen K, Christofaro D, Chudek J, Cifkova R, Cinteza E, Claessens F, Clays E, Concin H, Confortin S, Cooper C, Cooper R, Coppinger T, Costanzo S, Cottel D, Cowell C, Craig C, Crujeiras A, Cucu A, D'Arrigo G, d'Orsi E, Dallongeville J, Damasceno A, Damsgaard C, Danaei G, Dankner R, Dantoft T, Dastgiri S, Dauchet L, Davletov K, De Backer G, De Bacquer D, De Curtis A, de Gaetano G, De Henauw S, de Oliveira P, De Ridder K, De Smedt D, Deepa M, Deev A, Dehghan A, Delisle H, Delpeuch F, Deschamps V, Dhana K, Di Castelnuovo A, Dias-da-Costa J, Diaz A, Dika Z, Djalalinia S, Do H, Dobson A, Donati M, Donfrancesco C, Donoso S, Döring A, Dorobantu M, Dorosty A, Doua K, Drygas W, Duan J, Duante C, Duleva V, Dulskiene V, Dzerve V, Dziankowska-Zaborszczyk E, Egbagbe E, Eggertsen R, Eiben G, Ekelund U, El Ati J, Elliott P, Engle-Stone R, Erasmus R, Erem C, Eriksen L, Eriksson J, la Peña J, Evans A, Faeh D, Fall C, Sant'Angelo V, Farzadfar F, Felix-Redondo F, Ferguson T, Fernandes R, Fernández-Bergés D, Ferrante D, Ferrari M, Ferreccio C, Ferrieres J, Finn J, Fischer K, Flores E, Föger B, Foo L, Forslund A, Forsner M, Fouad H, Francis D, Franco M, Franco O, Frontera G, Fuchs F, Fuchs S, Fujita Y, Furusawa T, Gaciong Z, Gafencu M, Galeone D, Galvano F, Garcia-de-la-Hera M, Gareta D, Garnett S, Gaspoz J, Gasull M, Gates L, Geiger H, Geleijnse J, Ghasemian A, Giampaoli S, Gianfagna F, Gill T, Giovannelli J, Giwercman A, Godos J, Gogen S, Goldsmith R, Goltzman D, Gonçalves H, González-Leon M, González-Rivas J, Gonzalez-Gross M, Gottrand F, Graça A, Graff-Iversen S, Grafnetter D, Grajda A, Grammatikopoulou M, Gregor R, Grodzicki T, Grøntved A, Grosso G, Gruden G, Grujic V, Gu D, Gualdi-Russo E, Guallar-Castillón P, Guan O, Gudmundsson E, Gudnason V, Guerrero R, Guessous I, Guimaraes A, Gulliford M, Gunnlaugsdottir J, Gunter M, Guo X, Guo Y, Gupta P, Gupta R, Gureje O, Gurzkowska B, Gutierrez L, Gutzwiller F, Hadaegh F, Hadjigeorgiou C, Si-Ramlee K, Halkjær J, Hambleton I, Hardy R, Kumar R, Hassapidou M, Hata J, Hayes A, He J, Heidinger-Felso R, Heinen M, Hendriks M, Henriques A, Cadena L, Herrala S, Herrera V, Herter-Aeberli I, Heshmat R, Hihtaniemi I, Ho S, Ho S, Hobbs M, Hofman A, Hopman W, Horimoto A, Hormiga C, Horta B, Houti L, Howitt C, Htay T, Htet A, Htike M, Hu Y, Huerta J, Petrescu C, Huisman M, Husseini A, Huu C, Huybrechts I, Hwalla N, Hyska J, Iacoviello L, Iannone A, Ibarluzea J, Ibrahim M, Ikeda N, Ikram M, Irazola V, Islam M, Ismail A, Ivkovic V, Iwasaki M, Jackson R, Jacobs J, Jaddou H, Jafar T, Jamil K, Jamrozik K, Janszky I, Jarani J, Jasienska G, Jelakovic A, Jelakovic B, Jennings G, Jeong S, Jiang C, Jiménez-Acosta S, Joffres M, Johansson M, Jonas J, Jørgensen T, Joshi P, Jovic D, Józwiak J, Juolevi A, Jurak G, Jureša V, Kaaks R, Kafatos A, Kajantie E, Kalter-Leibovici O, Kamaruddin N, Kapantais E, Karki K, Kasaeian A, Katz J, Kauhanen J, Kaur P, Kavousi M, Kazakbaeva G, Keil U, Boker L, Keinänen-Kiukaanniemi S, Kelishadi R, Kelleher C, Kemper H, Kengne A, Kerimkulova A, Kersting M, Key T, Khader Y, Khalili D, Khang Y, Khateeb M, Khaw K, Khouw I, Kiechl-Kohlendorfer U, Kiechl S, Killewo J, Kim J, Kim Y, Klimont J, Klumbiene J, Knoflach M, Koirala B, Kolle E, Kolsteren P, Korrovits P, Kos J, Koskinen S, Kouda K, Kovacs V, Kowlessur S, Koziel S, Kratzer W, Kriemler S, Kristensen P, Krokstad S, Kromhout D, Kruger H, Kubinova R, Kuciene R, Kuh D, Kujala U, Kulaga Z, Kumar R, Kunešová M, Kurjata P, Kusuma Y, Kuulasmaa K, Kyobutungi C, La Q, Laamiri F, Laatikainen T, Lachat C, Laid Y, Lam T, Landrove O, Lanska V, Lappas G, Larijani B, Laugsand L, Lauria L, Laxmaiah A, Bao K, Le T, Lebanan M, Leclercq C, Lee J, Lee J, Lehtimäki T, León-Muñoz L, Levitt N, Li Y, Lilly C, Lim W, Lima-Costa M, Lin H, Lin X, Lind L, Linneberg A, Lissner L, Litwin M, Liu J, Loit H, Lopes L, Lorbeer R, Lotufo P, Lozano J, Luksiene D, Lundqvist A, Lunet N, Lytsy P, Ma G, Ma J, Machado-Coelho G, Machado-Rodrigues A, Machi S, Maggi S, Magliano D, Magriplis E, Mahaletchumy A, Maire B, Majer M, Makdisse M, Malekzadeh R, Malhotra R, Rao K, Malyutina S, Manios Y, Mann J, Manzato E, Margozzini P, Markaki A, Markey O, Marques L, Marques-Vidal P, Marrugat J, Martin-Prevel Y, Martin R, Martorell R, Martos E, Marventano S, Masoodi S, Mathiesen E, Matijasevich A, Matsha T, Mazur A, Mbanya J, McFarlane S, McGarvey S, McKee M, McLachlan S, McLean R, McLean S, McNulty B, Yusof S, Mediene-Benchekor S, Medzioniene J, Meirhaeghe A, Meisfjord J, Meisinger C, Menezes A, Menon G, Mensink G, Meshram I, Metspalu A, Meyer H, Mi J, Michaelsen K, Michels N, Mikkel K, Miller J, Minderico C, Miquel J, Miranda J, Mirkopoulou D, Mirrakhimov E, Mišigoj-Durakovic M, Mistretta A, Mocanu V, Modesti P, Mohamed M, Mohammad K, Mohammadifard N, Mohan V, Mohanna S, Yusoff M, Molbo D, Møllehave L, Møller N, Molnár D, Momenan A, Mondo C, Monterrubio E, Monyeki K, Moon J, Moreira L, Morejon A, Moreno L, Morgan K, Mortensen E, Moschonis G, Mossakowska M, Mostafa A, Mota J, Mota-Pinto A, Motlagh M, Motta J, Mu T, Muc M, Muiesan M, Müller-Nurasyid M, Murphy N, Mursu J, Murtagh E, Musil V, Nabipour I, Nagel G, Naidu B, Nakamura H, Námešná J, Nang E, Nangia V, Nankap M, Narake S, Nardone P, Navarrete-Muñoz E, Neal W, Nenko I, Neovius M, Nervi F, Nguyen C, Nguyen N, Nguyen Q, Nieto-Martínez R, Ning G, Ninomiya T, Nishtar S, Noale M, Noboa O, Norat T, Norie S, Noto D, Nsour M, O'Reilly D, Obreja G, Oda E, Oehlers G, Oh K, Ohara K, Olafsson Ö, Olinto M, Oliveira I, Oltarzewski M, Omar M, Onat A, Ong S, Ono L, Ordunez P, Ornelas R, Ortiz A, Osler M, Osmond C, Ostojic S, Ostovar A, Otero J, Overvad K, Owusu-Dabo E, Paccaud F, Padez C, Pahomova E, Pajak A, Palli D, Palloni A, Palmieri L, Pan W, Panda-Jonas S, Pandey A, Panza F, Papandreou D, Park S, Parnell W, Parsaeian M, Pascanu I, Patel N, Pecin I, Pednekar M, Peer N, Peeters P, Peixoto S, Peltonen M, Pereira A, Perez-Farinos N, Pérez C, Peters A, Petkeviciene J, Petrauskiene A, Peykari N, Pham S, Pierannunzio D, Pigeot I, Pikhart H, Pilav A, Pilotto L, Pistelli F, Pitakaka F, Piwonska A, Plans-Rubió P, Poh B, Pohlabeln H, Pop R, Popovic S, Porta M, Portegies M, Posch G, Poulimeneas D, Pouraram H, Pourshams A, Poustchi H, Pradeepa R, Prashant M, Price J, Puder J, Pudule I, Puiu M, Punab M, Qasrawi R, Qorbani M, Bao T, Radic I, Radisauskas R, Rahman M, Rahman M, Raitakari O, Raj M, Rao S, Ramachandran A, Ramke J, Ramos E, Ramos R, Rampal L, Rampal S, Rascon-Pacheco R, Redon J, Reganit P, Ribas-Barba L, Ribeiro R, Riboli E, Rigo F, de Wit T, Rito A, Ritti-Dias R, Rivera J, Robinson S, Robitaille C, Rodrigues D, Rodríguez-Artalejo F, del Cristo Rodriguez-Perez M, Rodríguez-Villamizar L, Rojas-Martinez R, Rojroongwasinkul N, Romaguera D, Ronkainen K, Rosengren A, Rouse I, Roy J, Rubinstein A, Rühli F, Ruiz-Betancourt B, Russo P, Rutkowski M, Sabanayagam C, Sachdev H, Saidi O, Salanave B, Martinez E, Salmerón D, Salomaa V, Salonen J, Salvetti M, Sánchez-Abanto J, Sandjaja, Sans S, Marina L, Santos D, Santos I, Santos O, dos Santos R, Santos R, Saramies J, Sardinha L, Sarrafzadegan N, Saum K, Savva S, Savy M, Scazufca M, Rosario A, Schargrodsky H, Schienkiewitz A, Schipf S, Schmidt C, Schmidt I, Schultsz C, Schutte A, Sein A, Sen A, Senbanjo I, Sepanlou S, Serra-Majem L, Shalnova S, Sharma S, Shaw J, Shibuya K, Shin D, Shin Y, Shiri R, Siani A, Siantar R, Sibai A, Silva A, Silva D, Simon M, Simons J, Simons L, Sjöberg A, Sjöström M, Skovbjerg S, Slowikowska-Hilczer J, Slusarczyk P, Smeeth L, Smith M, Snijder M, So H, Sobngwi E, Söderberg S, Soekatri M, Solfrizzi V, Sonestedt E, Song Y, Sørensen T, Soric M, Jérome C, Soumare A, Spinelli A, Spiroski I, Staessen J, Stamm H, Starc G, Stathopoulou M, Staub K, Stavreski B, Steene-Johannessen J, Stehle P, Stein A, Stergiou G, Stessman J, Stieber J, Stöckl D, Stocks T, Stokwiszewski J, Stratton G, Stronks K, Strufaldi M, Suárez-Medina R, Sun C, Sundström J, Sung Y, Sunyer J, Suriyawongpaisal P, Swinburn B, Sy R, Szponar L, Tai E, Tammesoo M, Tamosiunas A, Tan E, Tang X, Tanser F, Tao Y, Tarawneh M, Tarp J, Tarqui-Mamani C, Tautu O, Braunerová R, Taylor A, Tchibindat F, Theobald H, Theodoridis X, Thijs L, Thuesen B, Tjonneland A, Tolonen H, Tolstrup J, Topbas M, Topór-Madry R, Tormo M, Tornaritis M, Torrent M, Toselli S, Traissac P, Trichopoulos D, Trichopoulou A, Trinh O, Trivedi A, Tshepo L, Tsigga M, Tsugane S, Tulloch-Reid M, Tullu F, Tuomainen T, Tuomilehto J, Turley M, Tynelius P, Tzotzas T, Tzourio C, Ueda P, Ugel E, Ukoli F, Ulmer H, Unal B, Uusitalo H, Valdivia G, Vale S, Valvi D, van der Schouw Y, Van Herck K, Van Minh H, van Rossem L, Van Schoor N, van Valkengoed I, Vanderschueren D, Vanuzzo D, Vatten L, Vega T, Veidebaum T, Velasquez-Melendez G, Velika B, Veronesi G, Verschuren W, Victora C, Viegi G, Viet L, Viikari-Juntura E, Vineis P, Vioque J, Virtanen J, Visvikis-Siest S, Viswanathan B, Vlasoff T, Vollenweider P, Völzke H, Voutilainen S, Vrijheid M, Wade A, Wagner A, Waldhör T, Walton J, Bebakar W, Mohamud W, Wanderley R, Wang M, Wang Q, Wang Y, Wang Y, Wannamethee S, Wareham N, Weber A, Wedderkopp N, Weerasekera D, Whincup P, Widhalm K, Widyahening I, Wiecek A, Wijga A, Wilks R, Willeit J, Willeit P, Wilsgaard T, Wojtyniak B, Wong-McClure R, Wong J, Wong J, Wong T, Woo J, Woodward M, Wu F, Wu J, Wu S, Xu H, Xu L, Yamborisut U, Yan W, Yang X, Yardim N, Ye X, Yiallouros P, Yngve A, Yoshihara A, You Q, Younger-Coleman N, Yusoff F, Yusoff M, Zaccagni L, Zafiropulos V, Zainuddin A, Zambon S, Zampelas A, Zamrazilová H, Zdrojewski T, Zeng Y, Zhao D, Zhao W, Zheng W, Zheng Y, Zholdin B, Zhou M, Zhu D, Zhussupov B, Zimmermann E, Cisneros J, Bentham J, Di Cesare M, Bilano V, Bixby H, Zhou B, Stevens G, Riley L, Taddei C, Hajifathalian K, Lu Y, Savin S, Cowan M, Paciorek C, Chirita-Emandi A, Hayes A, Katz J, Kelishadi R, Kengne A, Khang Y, Laxmaiah A, Li Y, Ma J, Miranda J, Mostafa A, Neovius M, Padez C, Rampal L, Zhu A, Bennett J, Danaei G, Bhutta Z, Ezzati M. Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128·9 million children, adolescents, and adults. The Lancet 2017, 390: 2627-2642. PMID: 29029897, PMCID: PMC5735219, DOI: 10.1016/s0140-6736(17)32129-3.Peer-Reviewed Original ResearchConceptsMean body mass indexBody mass indexPrevalence of obesitySevere underweightAge-standardised mean body mass indexPrevalence of BMIGlobal age-standardised prevalenceCentral Latin AmericaAge-standardised prevalencePopulation-based studyAdolescent body mass indexAdverse health consequencesNon-significant increaseAndean Latin AmericaBMI categoriesWHO growth referencesMeasurements of heightPooled analysisHigh-income countriesObesityUnderweightHealth programsPrevalenceHealth consequencesGrowth referencesTrends in obesity and diabetes across Africa from 1980 to 2014: an analysis of pooled population-based studies
Kengne A, Bentham J, Zhou B, Peer N, Matsha T, Bixby H, Di Cesare M, Hajifathalian K, Lu Y, Taddei C, Bovet P, Kyobutungi C, Agyemang C, Aounallah-Skhiri H, Assah F, Barkat A, Romdhane H, Chan Q, Chaturvedi N, Damasceno A, Delisle H, Delpeuch F, Doua K, Egbagbe E, Ati J, Elliott P, Engle-Stone R, Erasmus R, Fouad H, Gareta D, Gureje O, Hendriks M, Houti L, Ibrahim M, Kemper H, Killewo J, Kowlessur S, Kruger H, Laamiri F, Laid Y, Levitt N, Lunet N, Magliano D, Maire B, Martin-Prevel Y, Mediene-Benchekor S, Mohamed M, Mondo C, Monyeki K, Mostafa A, Nankap M, Owusu-Dabo E, de Wit T, Saidi O, Schultsz C, Schutte A, Senbanjo I, Shaw J, Smeeth L, Sobngwi E, Jérome C, Stronks K, Tanser F, Tchibindat F, Traissac P, Tshepo L, Tullu F, Ukoli F, Viswanathan B, Wade A, Danaei G, Stevens G, Riley L, Ezzati M, Mbanya J. Trends in obesity and diabetes across Africa from 1980 to 2014: an analysis of pooled population-based studies. International Journal Of Epidemiology 2017, 46: 1421-1432. PMID: 28582528, PMCID: PMC5837192, DOI: 10.1093/ije/dyx078.Peer-Reviewed Original ResearchConceptsMean body mass indexBody mass indexAge-standardized mean body mass indexPopulation-based studyNon-communicable diseasesWorldwide population-based studyAge-standardized prevalenceBurden of diabetesDiabetes prevalence estimatesPopulation-based surveyDiabetes statusDiabetes prevalenceMass indexControl diabetesDiabetes estimatesDiabetesPrevalence estimatesPrevalenceObesityPositive associationWomenSaharan AfricaSexMenHigher numberSex Differences in Inflammatory Markers and Health Status Among Young Adults With Acute Myocardial Infarction
Lu Y, Zhou S, Dreyer RP, Spatz ES, Geda M, Lorenze NP, D'Onofrio G, Lichtman JH, Spertus JA, Ridker PM, Krumholz HM. Sex Differences in Inflammatory Markers and Health Status Among Young Adults With Acute Myocardial Infarction. Circulation Cardiovascular Quality And Outcomes 2017, 10: e003470. PMID: 28228461, PMCID: PMC5459381, DOI: 10.1161/circoutcomes.116.003470.Peer-Reviewed Original ResearchMeSH Keywords1-Alkyl-2-acetylglycerophosphocholine EsteraseAdolescentAdultAge of OnsetBiomarkersC-Reactive ProteinChi-Square DistributionComorbidityFemaleHealth Status DisparitiesHumansInflammation MediatorsLinear ModelsMaleMiddle AgedMultivariate AnalysisMyocardial InfarctionProspective StudiesRisk AssessmentRisk FactorsSex FactorsSocioeconomic FactorsUnited StatesUp-RegulationYoung AdultConceptsHigh-sensitivity C-reactive proteinAcute myocardial infarctionHigher inflammatory levelsInflammatory markersPoor health statusHealth statusYoung womenMyocardial infarctionInflammatory levelsTargeted anti-inflammatory treatmentsElevated inflammatory markersResidual cholesterol riskResidual inflammatory riskSex differencesAnti-inflammatory treatmentAnti-inflammatory therapyC-reactive proteinHigher mortality riskYoung menPhospholipase A2Years of ageCardiovascular outcomesMultivariable adjustmentPatient characteristicsSecondary prevention
2016
Sex differences in lipid profiles and treatment utilization among young adults with acute myocardial infarction: Results from the VIRGO study
Lu Y, Zhou S, Dreyer RP, Caulfield M, Spatz ES, Geda M, Lorenze NP, Herbert P, D'Onofrio G, Jackson EA, Lichtman JH, Bueno H, Spertus JA, Krumholz HM. Sex differences in lipid profiles and treatment utilization among young adults with acute myocardial infarction: Results from the VIRGO study. American Heart Journal 2016, 183: 74-84. PMID: 27979045, PMCID: PMC5459396, DOI: 10.1016/j.ahj.2016.09.012.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionLipid profileYoung womenLipoprotein cholesterolLipoprotein profileMyocardial infarctionTreatment utilizationLow-density lipoprotein cholesterolHigh-density lipoprotein cholesterolLow HDL cholesterol levelsYoung adultsHigh-intensity doseMajor lipid abnormalitiesSex differencesAdverse lipid profileFavorable lipoprotein profileHDL cholesterol ratioLower total cholesterolHDL cholesterol levelsHigher HDL cholesterolImportant risk factorHigher mortality riskMultivariate regression analysisVIRGO StudyCardiovascular outcomesTrends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19·2 million participants
Analysis and Writing P, Di Cesare M, Bentham J, Stevens G, Zhou B, Danaei G, Lu Y, Bixby H, Cowan M, Riley L, Hajifathalian K, Fortunato L, Taddei C, Bennett J, Ikeda N, Khang Y, Kyobutungi C, Laxmaiah A, Li Y, Lin H, Miranda J, Mostafa A, Turley M, Paciorek C, Gunter M, Ezzati M, Data C, Abdeen Z, Hamid Z, Abu-Rmeileh N, Acosta-Cazares B, Adams R, Aekplakorn W, Aguilar-Salinas C, Ahmadvand A, Ahrens W, Ali M, Alkerwi A, Alvarez-Pedrerol M, Aly E, Amouyel P, Amuzu A, Andersen L, Anderssen S, Andrade D, Anjana R, Aounallah-Skhiri H, Ariansen I, Aris T, Arlappa N, Arveiler D, Assah F, Avdicová M, Azizi F, Babu B, Balakrishna N, Bandosz P, Banegas J, Barbagallo C, Barceló A, Barkat A, Barros M, Bata I, Batieha A, Batista R, Baur L, Beaglehole R, Romdhane H, Benet M, Bernabe-Ortiz A, Bernotiene G, Bettiol H, Bhagyalaxmi A, Bharadwaj S, Bhargava S, Bhatti Z, Bhutta Z, Bi H, Bi Y, Bjerregaard P, Bjertness E, Bjertness M, Björkelund C, Blake M, Blokstra A, Bo S, Bobak M, Boddy L, Boehm B, Boeing H, Boissonnet C, Bongard V, Bovet P, Braeckman L, Bragt M, Brajkovich I, Branca F, Breckenkamp J, Brenner H, Brewster L, Brian G, Bruno G, Bueno-de-Mesquita H, Bugge A, Burns C, de León A, Cacciottolo J, Cama T, Cameron C, Camolas J, Can G, Cândido A, Capuano V, Cardoso V, Carvalho M, Casanueva F, Casas J, Caserta C, Castetbon K, Chamukuttan S, Chan A, Chan Q, Chaturvedi H, Chaturvedi N, Chen C, Chen F, Chen H, Chen S, Chen Z, Cheng C, Chetrit A, Chiolero A, Chiou S, Chirita-Emandi A, Cho Y, Christensen K, Chudek J, Cifkova R, Claessens F, Clays E, Concin H, Cooper C, Cooper R, Coppinger T, Costanzo S, Cottel D, Cowell C, Craig C, Crujeiras A, D’Arrigo G, d’Orsi E, Dallongeville J, Damasceno A, Damsgaard C, Danaei G, Dankner R, Dauchet L, De Backer G, De Bacquer D, de Gaetano G, De Henauw S, De Smedt D, Deepa M, Deev A, Dehghan A, Delisle H, Delpeuch F, Dhana K, Di Castelnuovo A, Dias-da-Costa J, Diaz A, Djalalinia S, P H, Dobson A, Donfrancesco C, Döring A, Doua K, Drygas W, Egbagbe E, Eggertsen R, Ekelund U, Ati J, Elliott P, Engle-Stone R, Erasmus R, Erem C, Eriksen L, la Peña J, Evans A, Faeh D, Fall C, Farzadfar F, Felix-Redondo F, Ferguson T, Fernández-Bergés D, Ferrante D, Ferrari M, Ferreccio C, Ferrieres J, Finn J, Fischer K, Flores E, Föger B, Foo L, Forslund A, Fortmann S, Fouad H, Francis D, do Carmo Franco M, Franco O, Frontera G, Fuchs F, Fuchs S, Fujita Y, Furusawa T, Gaciong Z, Gafencu M, Gareta D, Garnett S, Gaspoz J, Gasull M, Gates L, Geleijnse J, Ghasemian A, Giampaoli S, Gianfagna F, Giovannelli J, Giwercman A, Goldsmith R, Gross M, Rivas J, Gorbea M, Gottrand F, Graff-Iversen S, Grafnetter D, Grajda A, Grammatikopoulou M, Gregor R, Grodzicki T, Grøntved A, Gruden G, Grujic V, Gu D, Guan O, Gudnason V, Guerrero R, Guessous I, Guimaraes A, Gulliford M, Gunnlaugsdottir J, Gunter M, Guo X, Guo Y, Gupta P, Gureje O, Gurzkowska B, Gutierrez L, Gutzwiller F, Halkjær J, Hardy R, Kumar R, Hayes A, He J, Hendriks M, Cadena L, Heshmat R, Hihtaniemi I, Ho S, Ho S, Hobbs M, Hofman A, Hormiga C, Horta B, Houti L, Htay T, Htet A, Htike M, Hu Y, Hussieni A, Huu C, Huybrechts I, Hwalla N, Iacoviello L, Iannone A, Ibrahim M, Ikeda N, Ikram M, Irazola V, Islam M, Iwasaki M, Jackson R, Jacobs J, Jafar T, Jamil K, Jamrozik K, Jasienska G, Jiang C, Joffres M, Johansson M, Jonas J, Jørgensen T, Joshi P, Juolevi A, Jurak G, Jureša V, Kaaks R, Kafatos A, Kalter-Leibovici O, Kapantais E, Kasaeian A, Katz J, Kaur P, Kavousi M, Keil U, Boker L, Kelishadi R, Kemper H, Kengne A, Kersting M, Key T, Khader Y, Khalili D, Khang Y, Khaw K, Khouw I, Kiechl S, Killewo J, Kim J, Kiyohara Y, Klimont J, Kolle E, Kolsteren P, Korrovits P, Koskinen S, Kouda K, Koziel S, Kratzer W, Krokstad S, Kromhout D, Kruger H, Kula K, Kulaga Z, Kumar R, Kusuma Y, Kuulasmaa K, Kyobutungi C, Laamiri F, Laatikainen T, Lachat C, Laid Y, Lam T, Landrove O, Lanska V, Lappas G, Laugsand L, Laxmaiah A, Le Nguyen Bao K, Le T, Leclercq C, Lee J, Lee J, Lehtimäki T, Lekhraj R, León-Muñoz L, Li Y, Lim W, Lima-Costa M, Lin H, Lin X, Linneberg A, Lissner L, Litwin M, Liu J, Lorbeer R, Lotufo P, Lozano J, Luksiene D, Lundqvist A, Lunet N, Lytsy P, Ma G, Machi S, Maggi S, Magliano D, Makdisse M, Malekzadeh R, Malhotra R, Rao K, Manios Y, Mann J, Manzato E, Margozzini P, Markey O, Marques-Vidal P, Marrugat J, Martin-Prevel Y, Martorell R, Masoodi S, Matsha T, Mazur A, Mbanya J, McFarlane S, McGarvey S, McKee M, McLachlan S, McLean R, McNulty B, Yusof S, Mediene-Benchekor S, Meirhaeghe A, Meisinger C, Mendes L, Menezes A, Mensink G, Meshram I, Metspalu A, Mi J, Michaelsen K, Mikkel K, Miller J, Miquel J, Miranda J, Mišigoj-Duraković M, Mohamed M, Mohammad K, Mohammadifard N, Mohan V, Yusoff M, Molbo D, Møller N, Molnár D, Mondo C, Monterrubio E, Monyeki K, Moreira L, Morejon A, Moreno L, Morgan K, Mortensen E, Moschonis G, Mossakowska M, Mostafa A, Mota J, Motlagh M, Motta J, Mu T, Muiesan M, Müller-Nurasyid M, Murphy N, Mursu J, Murtagh E, Musa K, Musil V, Nagel G, Nakamura H, Námešná J, Nang E, Nangia V, Nankap M, Narake S, Navarrete-Muñoz E, Nenko I, Neovius M, Nervi F, Neuhauser H, Nguyen N, Nguyen Q, Nieto-Martínez R, Ning G, Ninomiya T, Nishtar S, Noale M, Norat T, Noto D, Al Nsour M, O’Reilly D, Ochoa-Avilés A, Oh K, Olayan I, Olinto M, Oltarzewski M, Omar M, Onat A, Ordunez P, Ortiz A, Osler M, Osmond C, Ostojic S, Otero J, Overvad K, Paccaud F, Padez C, Pajak A, Palli D, Palloni A, Palmieri L, Panda-Jonas S, Panza F, Parnell W, Parsaeian M, Pednekar M, Peeters P, Peixoto S, Pereira A, Pérez C, Peters A, Peykari N, Pham S, Pigeot I, Pikhart H, Pilav A, Pilotto L, Pistelli F, Pitakaka F, Piwonska A, Piwonski J, Plans-Rubió P, Poh B, Porta M, Portegies M, Poulimeneas D, Pradeepa R, Prashant M, Price J, Puiu M, Punab M, Qasrawi R, Qorbani M, Bao T, Radic I, Radisauskas R, Rahman M, Raitakari O, Raj M, Rao S, Ramachandran A, Ramke J, Ramos R, Rampal S, Rasmussen F, Redon J, Reganit P, Ribeiro R, Riboli E, Rigo F, de Wit T, Ritti-Dias R, Rivera J, Robinson S, Robitaille C, Rodríguez-Artalejo F, del Cristo Rodriguez-Perez M, Rodríguez-Villamizar L, Rojas-Martinez R, Rojroongwasinkul N, Romaguera D, Ronkainen K, Rosengren A, Rouse I, Rubinstein A, Rühli F, Rui O, Ruiz-Betancourt B, Horimoto A, Rutkowski M, Sabanayagam C, Sachdev H, Saidi O, Salanave B, Martinez E, Salomaa V, Salonen J, Salvetti M, Sánchez-Abanto J, Sandjaja, Sans S, Santos D, Santos O, dos Santos R, Santos R, Sardinha L, Sarrafzadegan N, Saum K, Savva S, Scazufca M, Rosario A, Schargrodsky H, Schienkiewitz A, Schmidt I, Schneider I, Schultsz C, Schutte A, Sein A, Sen A, Senbanjo I, Sepanlou S, Shalnova S, Shaw J, Shibuya K, Shin Y, Shiri R, Siantar R, Sibai A, Silva A, Silva D, Simon M, Simons J, Simons L, Sjostrom M, Slowikowska-Hilczer J, Slusarczyk P, Smeeth L, Smith M, Snijder M, So H, Sobngwi E, Soderberg S, Soekatri M, Solfrizzi V, Sonestedt E, Sørensen T, Sorić M, Jérome C, Soumare A, Staessen J, Starc G, Stathopoulou M, Staub K, Stavreski B, Steene-Johannessen J, Stehle P, Stein A, Stergiou G, Stessman J, Stieber J, Stöckl D, Stocks T, Stokwiszewski J, Stratton G, Strufaldi M, Sun C, Sundström J, Sung Y, Sunyer J, Suriyawongpaisal P, Swinburn B, Sy R, Szponar L, Tai E, Tammesoo M, Tamosiunas A, Tang L, Tang X, Tanser F, Tao Y, Tarawneh M, Tarp J, Tarqui-Mamani C, Taylor A, Tchibindat F, Thijs L, Thuesen B, Tjonneland A, Tolonen H, Tolstrup J, Topbas M, Topór-Madry R, Torrent M, Traissac P, Trichopoulou A, Trichopoulos D, Trinh O, Trivedi A, Tshepo L, Tulloch-Reid M, Tuomainen T, Tuomilehto J, Turley M, Tynelius P, Tzotzas T, Tzourio C, Ueda P, Ukoli F, Ulmer H, Unal B, Valdivia G, Vale S, Valvi D, van der Schouw Y, Van Herck K, Van Minh H, van Valkengoed I, Vanderschueren D, Vanuzzo D, Vatten L, Vega T, Velasquez-Melendez G, Veronesi G, Verschuren W, Viegi G, Viet L, Viikari-Juntura E, Vineis P, Vioque J, Virtanen J, Visvikis-Siest S, Viswanathan B, Vollenweider P, Voutilainen S, Vrijheid M, Wade A, Wagner A, Walton J, Mohamud W, Wang M, Wang Q, Wang Y, Wannamethee S, Wareham N, Weerasekera D, Whincup P, Widhalm K, Widyahening I, Wiecek A, Wilks R, Willeit J, Wojtyniak B, Wong J, Wong T, Woo J, Woodward M, Wu F, Wu J, Wu S, Xu H, Xu L, Yamborisut U, Yan W, Yang X, Yardim N, Ye X, Yiallouros P, Yoshihara A, You Q, Younger-Coleman N, Yusoff A, Zainuddin A, Zambon S, Zdrojewski T, Zeng Y, Zhao D, Zhao W, Zheng Y, Zhou M, Zhu D, Zimmermann E, Cisneros J. Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19·2 million participants. The Lancet 2016, 387: 1377-1396. PMID: 27115820, PMCID: PMC7615134, DOI: 10.1016/s0140-6736(16)30054-x.Peer-Reviewed Original ResearchConceptsBody-mass indexMean body-mass indexHighest prevalence of underweightPrevalence of BMI categoriesBody-mass index categoryAdult body-mass indexPopulation-based data sourcesPrevalence of underweightAge-standardised prevalencePrevalence of obesityAdverse health outcomesPopulation-based studyGlobal obesity prevalenceObesity prevalenceBMI categoriesPrevalence of morbid obesityHealth outcomesMeasured heightUnderweightAdult participantsElevated riskMorbid obesityWorld's poorest regionsObesity targetsEstimate trends
2012
A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010
Lim SS, Vos T, Flaxman AD, Danaei G, Shibuya K, Adair-Rohani H, AlMazroa M, Amann M, Anderson H, Andrews K, Aryee M, Atkinson C, Bacchus L, Bahalim A, Balakrishnan K, Balmes J, Barker-Collo S, Baxter A, Bell M, Blore J, Blyth F, Bonner C, Borges G, Bourne R, Boussinesq M, Brauer M, Brooks P, Bruce N, Brunekreef B, Bryan-Hancock C, Bucello C, Buchbinder R, Bull F, Burnett R, Byers T, Calabria B, Carapetis J, Carnahan E, Chafe Z, Charlson F, Chen H, Chen J, Cheng A, Child J, Cohen A, Colson K, Cowie B, Darby S, Darling S, Davis A, Degenhardt L, Dentener F, Jarlais D, Devries K, Dherani M, Ding E, Dorsey E, Driscoll T, Edmond K, Ali S, Engell R, Erwin P, Fahimi S, Falder G, Farzadfar F, Ferrari A, Finucane M, Flaxman S, Fowkes F, Freedman G, Freeman M, Gakidou E, Ghosh S, Giovannucci E, Gmel G, Graham K, Grainger R, Grant B, Gunnell D, Gutierrez H, Hall W, Hoek H, Hogan A, Hosgood H, Hoy D, Hu H, Hubbell B, Hutchings S, Ibeanusi S, Jacklyn G, Jasrasaria R, Jonas J, Kan H, Kanis J, Kassebaum N, Kawakami N, Khang Y, Khatibzadeh S, Khoo J, Kok C, Laden F, Lalloo R, Lan Q, Lathlean T, Leasher J, Leigh J, Li Y, Lin J, Lipshultz S, London S, Lozano R, Lu Y, Mak J, Malekzadeh R, Mallinger L, Marcenes W, March L, Marks R, Martin R, McGale P, McGrath J, Mehta S, Memish Z, Mensah G, Merriman T, Micha R, Michaud C, Mishra V, Hanafiah K, Mokdad A, Morawska L, Mozaffarian D, Murphy T, Naghavi M, Neal B, Nelson P, Nolla J, Norman R, Olives C, Omer S, Orchard J, Osborne R, Ostro B, Page A, Pandey K, Parry C, Passmore E, Patra J, Pearce N, Pelizzari P, Petzold M, Phillips M, Pope D, Pope C, Powles J, Rao M, Razavi H, Rehfuess E, Rehm J, Ritz B, Rivara F, Roberts T, Robinson C, Rodriguez-Portales J, Romieu I, Room R, Rosenfeld L, Roy A, Rushton L, Salomon J, Sampson U, Sanchez-Riera L, Sanman E, Sapkota A, Seedat S, Shi P, Shield K, Shivakoti R, Singh G, Sleet D, Smith E, Smith K, Stapelberg N, Steenland K, Stöckl H, Stovner L, Straif K, Straney L, Thurston G, Tran J, Van Dingenen R, van Donkelaar A, Veerman J, Vijayakumar L, Weintraub R, Weissman M, White R, Whiteford H, Wiersma S, Wilkinson J, Williams H, Williams W, Wilson N, Woolf A, Yip P, Zielinski J, Lopez A, Murray C, Ezzati M. A comparative risk assessment of burden of disease and injury attributable to 67 risk factors and risk factor clusters in 21 regions, 1990–2010: a systematic analysis for the Global Burden of Disease Study 2010. The Lancet 2012, 380: 2224-2260. PMID: 23245609, PMCID: PMC4156511, DOI: 10.1016/s0140-6736(12)61766-8.Peer-Reviewed Original ResearchConceptsSecond-hand smokeDisease Study 2010High blood pressureRisk factorsDisease burdenGlobal disease burdenTobacco smokingRisk factor exposureBlood pressureGlobal DALYsChildhood underweightRelative riskGlobal burdenStudy 2010Unimproved waterCommunicable diseasesHigh-income North AmericaHigher body mass indexAlcohol useChildhood communicable diseasesDisability-adjusted life yearsRisk factor clustersDietary risk factorsCause-specific deathBody mass index
2011
National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9·1 million participants
Finucane MM, Stevens GA, Cowan MJ, Danaei G, Lin JK, Paciorek CJ, Singh GM, Gutierrez HR, Lu Y, Bahalim AN, Farzadfar F, Riley LM, Ezzati M, Group O. National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9·1 million participants. The Lancet 2011, 377: 557-567. PMID: 21295846, PMCID: PMC4472365, DOI: 10.1016/s0140-6736(10)62037-5.Peer-Reviewed Original ResearchMeSH KeywordsAdultBayes TheoremBody Mass IndexFemaleGlobal HealthHealth SurveysHumansLogistic ModelsMaleYoung AdultConceptsBody mass indexHealth Examination SurveyHigher body mass indexFemale body mass indexMale body mass indexExamination SurveyEpidemiological studiesPopulation body mass indexMean body mass indexMajor public health concernNational Health Examination SurveyAdults 20 yearsPublic health concernNon-significant decreaseBMI changeExcess bodyweightMetabolic mediatorsHigh-income countriesHealth concernMelinda Gates FoundationHealth effectsWomenMenSaharan AfricaGates Foundation