2007
A Novel CaV1.2 N Terminus Expressed in Smooth Muscle Cells of Resistance Size Arteries Modifies Channel Regulation by Auxiliary Subunits*
Cheng X, Liu J, Asuncion-Chin M, Blaskova E, Bannister J, Dopico A, Jaggar J. A Novel CaV1.2 N Terminus Expressed in Smooth Muscle Cells of Resistance Size Arteries Modifies Channel Regulation by Auxiliary Subunits*. Journal Of Biological Chemistry 2007, 282: 29211-29221. PMID: 17699517, PMCID: PMC2276565, DOI: 10.1074/jbc.m610623200.Peer-Reviewed Original ResearchConceptsExon 1cN-terminusExon 1bAuxiliary subunitsRich N-terminusCysteine-rich N-terminusNovel alternative splicingResistance-size cerebral arteriesPlasma membrane insertionExon 1Arterial myocytesMultiple vascular functionsIsoform-dependent differencesWhole-cell current densityN-terminal variantsAlternative splicingMembrane insertionChannel regulationExon 1AMolecular identityHuman diseasesSubunitsTerminusEntry pathwaySmooth muscle cells
2001
Inhibition of Ryanodine Binding to Sarcoplasmic Reticulum Vesicles of Cardiac Muscle by Zn2+ Ions
Wang H, Wei Q, Cheng X, Chen K, Zhu P. Inhibition of Ryanodine Binding to Sarcoplasmic Reticulum Vesicles of Cardiac Muscle by Zn2+ Ions. Cellular Physiology And Biochemistry 2001, 11: 83-92. PMID: 11275686, DOI: 10.1159/000047795.Peer-Reviewed Original ResearchConceptsInhibitory effectCardiac muscleModulators of RyRSarcoplasmic reticulumSkeletal muscleSarcoplasmic reticulum vesiclesMuscleScatchard analysisRyanodine receptorRyanodine bindingRyRsThiol-reducing agentsPhysiological significanceReticulum vesiclesHill coefficientObvious changeActivation siteMM dithiothreitol