Biphasic modulation of ryanodine binding to sarcoplasmic reticulum vesicles of skeletal muscle by Zn2+ ions
XIA R, CHENG X, Hui W, CHEN K, WEI Q, ZHANG X, ZHU P. Biphasic modulation of ryanodine binding to sarcoplasmic reticulum vesicles of skeletal muscle by Zn2+ ions. Biochemical Journal 2000, 345: 279-286. PMID: 10620505, PMCID: PMC1220757, DOI: 10.1042/bj3450279.Peer-Reviewed Original ResearchConceptsSarcoplasmic reticulum vesiclesReticulum vesiclesBiphasic modulationSkeletal muscle ryanodine receptorPeak bindingInhibitory effectMuscle ryanodine receptorHeavy sarcoplasmic reticulum vesiclesSkeletal muscleScatchard analysisRyanodine receptorBiphasic time courseRyanodine bindingTime courseMicroMThiol-reducing agentsPhysiological significanceInactivation site