2006
Genetic Ablation of Caveolin‐1 Modifies Ca2+ Spark Coupling in Murine Arterial Smooth Muscle Cells
Cheng X, Jaggar J. Genetic Ablation of Caveolin‐1 Modifies Ca2+ Spark Coupling in Murine Arterial Smooth Muscle Cells. The FASEB Journal 2006, 20: a1173-a1174. DOI: 10.1096/fasebj.20.5.a1173-d.Peer-Reviewed Original ResearchSmooth muscle cellsKCa channelsMurine arterial smooth muscle cellsCerebral artery smooth muscle cellsL-type voltage-dependent calcium channelsGenetic ablationMuscle cellsArtery smooth muscle cellsSpark frequencyVoltage-dependent calcium channelsArterial smooth muscle cellsSmooth muscle contractilityLarge-conductance Ca2Ryanodine-sensitive Ca2Caveolin-1-deficient miceKCa currentsNOS activityDeficient miceChannel blockersMuscle contractilityCoupling of Ca2SR Ca2Calcium channelsIntracellular Ca2Alters Ca2
2002
Carbon Monoxide Dilates Cerebral Arterioles by Enhancing the Coupling of Ca2+ Sparks to Ca2+-Activated K+ Channels
Jaggar J, Leffler C, Cheranov S, Tcheranova D, E S, Cheng X. Carbon Monoxide Dilates Cerebral Arterioles by Enhancing the Coupling of Ca2+ Sparks to Ca2+-Activated K+ Channels. Circulation Research 2002, 91: 610-617. PMID: 12364389, DOI: 10.1161/01.res.0000036900.76780.95.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsArteriolesCalcium Channel BlockersCalcium SignalingCarbon MonoxideCells, CulturedCerebral ArteriesCulture TechniquesElectric ConductivityHemeKineticsLysineMuscle, Smooth, VascularPotassium Channels, Calcium-ActivatedRyanodineRyanodine Receptor Calcium Release ChannelSignal TransductionSwineVasodilationVasodilator AgentsConceptsCerebral arteriolesArteriole smooth muscle cellsRelease channel blockerSmooth muscle cellsLarge-conductance Ca2Ryanodine-sensitive Ca2Enzyme heme oxygenasePial arteriolesCerebral circulationChannel blockersCoupling of Ca2Cellular signaling mechanismsPotent effectsArteriolesMuscle cellsHeme oxygenaseVasodilatorsPotent activatorControl conditionDilationPresent studySignaling mechanismCa2Source of controversyPercentage of Ca2