2023
In Situ Simulation and Clinical Outcomes in Infants Born Preterm
Chitkara R, Bennett M, Bohnert J, Yamada N, Fuerch J, Halamek L, Quinn J, Padua K, Gould J, Profit J, Xu X, Lee H. In Situ Simulation and Clinical Outcomes in Infants Born Preterm. The Journal Of Pediatrics 2023, 263: 113715. PMID: 37659586, PMCID: PMC10841094, DOI: 10.1016/j.jpeds.2023.113715.Peer-Reviewed Original ResearchConceptsChronic lung diseaseClinical outcomesNeonatal resuscitationDelivery room continuous positive airway pressureVery low birth weight birthsNeonatal intensive care unit admissionCalifornia Perinatal Quality Care CollaborativeContinuous positive airway pressureVery low birth weightSecondary outcomesNeonatal intensive care unitInfants born pretermLow birth weight birthsSevere intraventricular hemorrhageIntensive care unit admissionPositive airway pressureLow birth weightInfant born pretermEvaluate clinical outcomesIntensive care unitParticipating sitesIntraventricular hemorrhageWeeks gestationBorn pretermCollaborative quality improvement project
2022
Maternal Outcomes in Subsequent Pregnancies After Classical Cesarean Delivery
Thompson BB, Reddy UM, Burn M, Abdel-Razeq S, Xu X. Maternal Outcomes in Subsequent Pregnancies After Classical Cesarean Delivery. Obstetrics And Gynecology 2022, 140: 212-219. PMID: 35852271, DOI: 10.1097/aog.0000000000004869.Peer-Reviewed Original ResearchConceptsPrior classical cesarean deliveryLow transverse cesarean deliveryPrior low transverse cesarean deliveryClassical cesarean deliverySevere maternal morbidityClinical risk factorsCesarean deliveryUterine ruptureMaternal outcomesSubsequent pregnancyHospital characteristicsRate of SMMPatient clinical risk factorsNational Inpatient Sample databaseLive singleton birthsWeeks of gestationMode of deliveryCross-sectional analysisMaternal morbiditySingleton birthsRisk factorsOutcome measuresMultivariable regressionHigh riskPropensity score methods
2020
Trial of Labor After Two Prior Cesarean Deliveries: Patient and Hospital Characteristics and Birth Outcomes.
Dombrowski M, Illuzzi JL, Reddy UM, Lipkind HS, Lee HC, Lin H, Lundsberg LS, Xu X. Trial of Labor After Two Prior Cesarean Deliveries: Patient and Hospital Characteristics and Birth Outcomes. Obstetrics And Gynecology 2020, 136: 109-117. PMID: 32541284, PMCID: PMC7321852, DOI: 10.1097/aog.0000000000003845.Peer-Reviewed Original ResearchConceptsComposite severe maternal morbidityTrial of laborPrior cesarean deliverySevere maternal morbidityCesarean deliveryMaternal morbidityNewborn complicationsHospital characteristicsPropensity score-matched analysisSevere neonatal morbiditySuccessful vaginal birthSingleton live birthsAssociation of patientCohort of mothersBirth certificate dataSample eligibility criteriaModest increaseNeonatal morbidityNeonatal outcomesHospital dischargeBirth outcomesVaginal birthClear contraindicationsLive birthsMultivariable regression
2019
Low‐Interventional Approaches to Intrapartum Care: Hospital Variation in Practice and Associated Factors
Lundsberg LS, Main EK, Lee HC, Lin H, Illuzzi JL, Xu X. Low‐Interventional Approaches to Intrapartum Care: Hospital Variation in Practice and Associated Factors. Journal Of Midwifery & Women's Health 2019, 65: 33-44. PMID: 31502407, DOI: 10.1111/jmwh.13017.Peer-Reviewed Original ResearchConceptsIntrapartum careMultivariable logistic regressionHigh intervention groupLow-intervention groupMedical-legal concernsIntrapartum practicesNewborn morbidityHospital variationCesarean birthAssociated FactorsPatient outcomesInterventional approachesProcedure ratesAmerican CollegeHospital useHospital's likelihoodHospital groupHospitalBivariate analysisLogistic regressionMidwifery modelCalifornia hospitalsCareLatent class analysisHospital culture
2018
Hospital variation in utilization and success of trial of labor after a prior cesarean
Xu X, Lee HC, Lin H, Lundsberg LS, Campbell KH, Lipkind HS, Pettker CM, Illuzzi JL. Hospital variation in utilization and success of trial of labor after a prior cesarean. American Journal Of Obstetrics And Gynecology 2018, 220: 98.e1-98.e14. PMID: 30278176, DOI: 10.1016/j.ajog.2018.09.034.Peer-Reviewed Original ResearchMeSH KeywordsAdultCaliforniaCesarean SectionCohort StudiesDatabases, FactualFemaleGestational AgeHospitals, High-VolumeHospitals, Low-VolumeHumansInfant, NewbornMaternal AgePatient SafetyPregnancyPregnancy OutcomeRetrospective StudiesRisk AssessmentTrial of LaborUterine RuptureVaginal Birth after CesareanConceptsSuccess of trialCesarean deliveryTrial of laborHospital variationSuccess rateLow success rateNewborn hospital discharge recordsPatient clinical risk factorsSevere unexpected newborn complicationsNewborn respiratory complicationsUnexpected newborn complicationsClinical risk factorsPrior cesarean deliveryHospital discharge recordsPatient case mixBirth certificate dataMidwife-attended birthsAnesthesia availabilityNewborn infectionRespiratory complicationsUterine ruptureNewborn morbidityPrior cesareanNewborn complicationsVaginal birthOptimal maternal and neonatal outcomes and associated hospital characteristics
Campbell KH, Illuzzi JL, Lee HC, Lin H, Lipkind HS, Lundsberg LS, Pettker CM, Xu X. Optimal maternal and neonatal outcomes and associated hospital characteristics. Birth 2018, 46: 289-299. PMID: 30251270, DOI: 10.1111/birt.12400.Peer-Reviewed Original ResearchMeSH KeywordsAdultBirth CertificatesCaliforniaCesarean SectionFemaleGestational AgeHospitalsHumansInfant, NewbornInfant, Newborn, DiseasesMorbidityObstetric Labor ComplicationsObstetricsPatient DischargePoisson DistributionPregnancyQuality Indicators, Health CareRegression AnalysisRisk FactorsYoung AdultConceptsRisk-standardized ratesMorbidity rateNeonatal outcomesObstetrical performancePatient clinical risk factorsFuture quality improvement effortsMaternal morbidity ratesNeonatal morbidity ratesProcedures/surgeriesSevere newborn morbiditySevere maternal morbidityClinical risk factorsShock/resuscitationHospital discharge recordsMaternal-newborn outcomesQuality improvement effortsPrevalent morbidityMaternal morbidityNeonatal morbidityRespiratory complicationsIntravascular coagulationNewborn morbidityHeart failureTerm birthsHospital variation
2017
Hospital variation in cost of childbirth and contributing factors: a cross‐sectional study
Xu X, Lee H, Lin H, Lundsberg L, Pettker C, Lipkind H, Illuzzi J. Hospital variation in cost of childbirth and contributing factors: a cross‐sectional study. BJOG An International Journal Of Obstetrics & Gynaecology 2017, 125: 829-839. PMID: 29090498, DOI: 10.1111/1471-0528.15007.Peer-Reviewed Original ResearchConceptsChildbirth hospitalisationsHospital variationObstetric interventionsHospital variancePatient clinical risk factorsSevere maternal morbiditySevere newborn morbidityClinical risk factorsMaternal sociodemographic characteristicsHospital discharge dataCross-sectional studyUrban-rural statusCross-sectional analysisCosts of childbirthHigh-cost hospitalsVertex birthsMaternal morbidityCaesarean deliveryNewborn morbidityBirth attendantsRisk factorsHospital typeCare capacityHospitalisationBetter outcomesEconomic evaluation of a behavioral intervention versus brief advice for substance use treatment in pregnant women: results from a randomized controlled trial
Xu X, Yonkers KA, Ruger JP. Economic evaluation of a behavioral intervention versus brief advice for substance use treatment in pregnant women: results from a randomized controlled trial. BMC Pregnancy And Childbirth 2017, 17: 83. PMID: 28270105, PMCID: PMC5341449, DOI: 10.1186/s12884-017-1260-5.Peer-Reviewed Original ResearchConceptsBrief adviceMET-CBTClinical outcomesPregnant womenPsychotropic medicationsHealth care system perspectiveBehavioral interventionsSevere substance use disordersIntervention costsSimilar clinical outcomesOverall medical costsNon-medical costsCost of careCost-minimization analysisSubstance use disordersQuality of lifeWilcoxon rank sum testSubstance use treatmentMotivational enhancement therapyCognitive behavioral therapyRank sum testFetal morbidityPostpartum periodClinical trialsIntake assessment
2016
Variation in Hospital Intrapartum Practices and Association With Cesarean Rate
Lundsberg LS, Illuzzi JL, Gariepy AM, Sheth SS, Pettker CM, Lee HC, Lipkind HS, Xu X. Variation in Hospital Intrapartum Practices and Association With Cesarean Rate. Journal Of Obstetric Gynecologic & Neonatal Nursing 2016, 46: 5-17. PMID: 27886948, DOI: 10.1016/j.jogn.2016.07.011.Peer-Reviewed Original ResearchConceptsCesarean rateIntrapartum practicesIntrapartum interventionsIntrapartum careLow-risk womenLower cesarean ratesRegular reviewHospital cesarean rateCross-sectional surveyRank sum testKendall's tau-b correlation coefficientLiberal indicationsLabor inductionVaginal birthHospital variationNewborn careAntibody screenCesarean birthIntravenous lineObstetric servicesHospital characteristicsEligible hospitalsMassachusetts hospitalsFetal monitoringClinical staff
2015
Cost-Effectiveness of Immediate Compared With Delayed Postpartum Etonogestrel Implant Insertion
Gariepy AM, Duffy JY, Xu X. Cost-Effectiveness of Immediate Compared With Delayed Postpartum Etonogestrel Implant Insertion. Obstetrics And Gynecology 2015, 126: 47-55. PMID: 26241255, PMCID: PMC4526123, DOI: 10.1097/aog.0000000000000907.Peer-Reviewed Original ResearchConceptsImplant insertionUnintended pregnancyContraceptive implantsImmediate postpartum implant insertionHealth care system perspectiveEtonogestrel implant insertionImmediate implant insertionImmediate postpartum provisionIncremental cost-effectiveness ratioFirst postpartum yearFuture unintended pregnanciesAlternative contraceptive methodsOne-way sensitivity analysesCost-effectiveness ratioForm of contraceptionDecision analytic modelPostpartum visitPostpartum yearYear postpartumPostpartum placementContraceptive failureMedical costsContraceptive methodsPregnancyImmediate insertionWide Variation Found In Hospital Facility Costs For Maternity Stays Involving Low-Risk Childbirth
Xu X, Gariepy A, Lundsberg LS, Sheth SS, Pettker CM, Krumholz HM, Illuzzi JL. Wide Variation Found In Hospital Facility Costs For Maternity Stays Involving Low-Risk Childbirth. Health Affairs 2015, 34: 1212-1219. PMID: 26153317, DOI: 10.1377/hlthaff.2014.1088.Peer-Reviewed Original ResearchConceptsCesarean deliveryHospital costsMaternity staysSerious maternal morbidityNationwide Inpatient SampleCoordination of careValue of careMaternal morbidityHospital admissionInpatient SampleDelivery system reformRural hospitalsUS hospitalsHospital practiceSafe reductionHospitalChildbirthStayLong stayHigh rateCareLower proportionUnited StatesFacility costsProbability of pregnancy after sterilization: a comparison of hysteroscopic versus laparoscopic sterilization
Gariepy AM, of: O, Creinin M, Smith K, Xu X. Probability of pregnancy after sterilization: a comparison of hysteroscopic versus laparoscopic sterilization. Contraception 2015, 91: 521. PMID: 25769439, DOI: 10.1016/j.contraception.2015.03.005.Commentaries, Editorials and Letters
2014
Probability of pregnancy after sterilization: a comparison of hysteroscopic versus laparoscopic sterilization
Gariepy AM, Creinin MD, Smith KJ, Xu X. Probability of pregnancy after sterilization: a comparison of hysteroscopic versus laparoscopic sterilization. Contraception 2014, 90: 174-181. PMID: 24767963, DOI: 10.1016/j.contraception.2014.03.010.Peer-Reviewed Original ResearchConceptsProbability of pregnancyLaparoscopic bipolar coagulationLaparoscopic sterilizationPregnancy rateBipolar coagulationHysteroscopic sterilizationCumulative pregnancy rateRisk of pregnancyBase-case analysisUse failure ratesFemale sterilization proceduresSterilization proceduresLaparoscopic bandPregnancy riskProcedure successHysteroscopicPregnancy probabilityCumulative riskPregnancyPopulation riskCoil placementWomenRiskAvailable dataFailure rateCosts of a Motivational Enhancement Therapy Coupled with Cognitive Behavioral Therapy versus Brief Advice for Pregnant Substance Users
Xu X, Yonkers KA, Ruger JP. Costs of a Motivational Enhancement Therapy Coupled with Cognitive Behavioral Therapy versus Brief Advice for Pregnant Substance Users. PLOS ONE 2014, 9: e95264. PMID: 24760017, PMCID: PMC3997437, DOI: 10.1371/journal.pone.0095264.Peer-Reviewed Original Research
2010
Pelvic Floor Consequences of Cesarean Delivery on Maternal Request in Women with a Single Birth: A Cost-effectiveness Analysis
Xu X, Ivy JS, Patel DA, Patel SN, Smith DG, Ransom SB, Fenner D, DeLancey JO. Pelvic Floor Consequences of Cesarean Delivery on Maternal Request in Women with a Single Birth: A Cost-effectiveness Analysis. Journal Of Women's Health 2010, 19: 147-160. PMID: 20088671, PMCID: PMC2828240, DOI: 10.1089/jwh.2009.1404.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsCesarean SectionCost-Benefit AnalysisDecision Support TechniquesDelivery, ObstetricElective Surgical ProceduresFecal IncontinenceFemaleGravidityHumansMonte Carlo MethodPelvic FloorPelvic Organ ProlapsePregnancyPregnancy OutcomeQuality of LifeQuality-Adjusted Life YearsTrial of LaborUrinary IncontinenceConceptsPelvic floor disordersTrial of laborObstetric indicationsCost-effectiveness analysisCesarean deliveryPrimigravid womenMaternal requestQuality of lifeSingle childbirthMaternal morbidityNeonatal outcomesPerinatal morbidityEmergency hysterectomyLifelong managementMean costSocietal perspectiveSingle birthsWomenCDMRMorbidityMortalityChildbirthIndicationsDeliveryPotential benefits
2008
Malpractice Burden, Rural Location, and Discontinuation of Obstetric Care: A Study of Obstetric Providers in Michigan
Xu X, Siefert KA, Jacobson PD, Lori JR, Gueorguieva I, Ransom SB. Malpractice Burden, Rural Location, and Discontinuation of Obstetric Care: A Study of Obstetric Providers in Michigan. The Journal Of Rural Health 2008, 25: 33-42. PMID: 19166559, PMCID: PMC3063488, DOI: 10.1111/j.1748-0361.2009.00196.x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedCareer MobilityFamily PracticeFemaleGynecologyHumansInsurance, LiabilityLiability, LegalMalpracticeMichiganMiddle AgedMultivariate AnalysisObstetricsPractice Management, MedicalPregnancyProfessional Practice LocationRegression AnalysisRiskRural Health ServicesUrban Health ServicesWorkforceConceptsObstetric careFamily physiciansRural family physiciansMalpractice burdenObstetric providersHigher likelihoodUrban family physiciansRural-urban differencesObstetrical servicesPhysicians' likelihoodPhysician's decisionCare supplyPhysiciansFuture interventionsCareRural locationsRural-urban locationDiscontinuationPractice environmentRegression analysisBurdenProfessional liability problemsMedical liability crisisMore researchRural Michigan
2007
The effects of medical liability on obstetric care supply in Michigan
Xu X, Siefert KA, Jacobson PD, Lori JR, Ransom SB. The effects of medical liability on obstetric care supply in Michigan. American Journal Of Obstetrics And Gynecology 2007, 198: 205.e1-205.e9. PMID: 17997388, PMCID: PMC2259238, DOI: 10.1016/j.ajog.2007.08.043.Peer-Reviewed Original ResearchMeSH KeywordsAttitude of Health PersonnelDecision MakingDelivery, ObstetricFamily PracticeFemaleHealth Services AccessibilityHumansInsurance, LiabilityLiability, LegalMaleMalpracticeMaternal Health ServicesMichiganMiddle AgedNurse MidwivesObstetricsPregnancyProfessional PracticeRiskSurveys and QuestionnairesWorkforceConceptsObstetric careFamily physiciansCare supplyHigh-risk obstetric careProvider decisionsProvision of careWarrants further researchPatient accessCare provisionCareMalpractice concernsObstetricsProviders' provisionMalpractice litigationPhysiciansPractice decisionsRiskMedical liabilityStatewide surveyFurther researchBabiesFactors