2024
Dendritic cells in food allergy, treatment, and tolerance
Liu E, Yin X, Siniscalco E, Eisenbarth S. Dendritic cells in food allergy, treatment, and tolerance. Journal Of Allergy And Clinical Immunology 2024, 154: 511-522. PMID: 38971539, PMCID: PMC11414995, DOI: 10.1016/j.jaci.2024.06.017.Peer-Reviewed Original ResearchAntigen presenting cellsDendritic cellsFood allergyOral tolerancePresenting cellsAllergic sensitizationPeripheral T regulatory cellsDevelopment of oral toleranceGut dendritic cellsT regulatory cellsDendritic cell subsetsLimited treatment optionsAdaptive immune responsesFood immunotherapyEpicutaneous immunotherapyCell subsetsTolerogenic programAlarmin releaseTreatment optionsLangerhans cellsFood toleranceInnocuous antigensSurface markersInflammatory conditionsImmune response
2021
Dendritic Cell Regulation of T Helper Cells
Yin X, Chen S, Eisenbarth SC. Dendritic Cell Regulation of T Helper Cells. Annual Review Of Immunology 2021, 39: 1-32. PMID: 33710920, DOI: 10.1146/annurev-immunol-101819-025146.Peer-Reviewed Original ResearchConceptsDendritic cellsProfessional antigen-presenting cellsDendritic Cell RegulationDifferent DC subsetsT helper cellsAntigen-presenting cellsAdaptive immune responsesT lymphocyte differentiationTh cell differentiationDC subsetsRegulatory cellsDistinct CD4Follicular helperImmune toleranceSubset phenotypesImmune activationHelper cellsImmune cellsImmune responseImmune systemHeterogeneous subsetLymphocyte differentiationLocal tissue microenvironmentTissue microenvironmentCellsAntigen-Presenting Cells in Food Tolerance and Allergy
Liu EG, Yin X, Swaminathan A, Eisenbarth SC. Antigen-Presenting Cells in Food Tolerance and Allergy. Frontiers In Immunology 2021, 11: 616020. PMID: 33488627, PMCID: PMC7821622, DOI: 10.3389/fimmu.2020.616020.Peer-Reviewed Original ResearchConceptsAntigen-presenting cellsDendritic cellsOral toleranceFood allergyT cellsDifferent antigen-presenting cellsB cell antibody responseLife-threatening anaphylaxisT cell responsesImmunoglobulin E antibodiesVariety of symptomsAPC subsetsFood antigensFood toleranceAntibody responseE antibodiesAntigen presentationImmune responseMouse modelFood allergensAllergyInitial primingCell responsesPatient samplesAntigen