2024
Association of Family Support With Lower Modifiable Risk Factors for Dementia Among Cognitively Impaired Older Adults
Lin Z, Yin X, Levy B, Yuan Y, Chen X. Association of Family Support With Lower Modifiable Risk Factors for Dementia Among Cognitively Impaired Older Adults. American Journal Of Geriatric Psychiatry 2024, 32: 1187-1199. PMID: 38839462, PMCID: PMC11366488, DOI: 10.1016/j.jagp.2024.05.005.Peer-Reviewed Original ResearchModifiable risk factorsCognitively impaired older adultsOlder adultsFamily supportResidential proximitySpousal presenceRisk factorsDepressive symptomsCognitive impairmentModifiable dementia risk factorsHealth and Retirement StudyProportion of older adultsDementia risk factorsSocial isolationDegree of family supportPercentage of smokingMixed-effects logistic regressionRobust to various sensitivity analysesCo-resident childrenRetirement StudySocial supportNo spouseLogistic regressionSpousesProtective factorsAssociation between experiencing low healthcare quality and developing dementia
Aravena J, Chen X, Levy B. Association between experiencing low healthcare quality and developing dementia. Journal Of The American Geriatrics Society 2024, 72: 2126-2132. PMID: 38415796, PMCID: PMC11226361, DOI: 10.1111/jgs.18842.Peer-Reviewed Original ResearchAssociated with increased dementia riskHealthcare qualityDementia riskHealthcare discriminationAssociated with greater dementia riskHazard ratioHealth and Retirement StudyDeterminants of dementiaCases of dementiaDementia prevalenceReducing dementiaPhysician diagnosisRetirement StudyHealthcare servicesOlder personsOlder adultsSocioeconomic factorsDementiaHealthcareImplement structural changesCognitive scoresCox regressionParticipantsHealthIndividual-level behaviorA Systematic Analysis of Early Life Exposure to the Chinese Famine (1959–1961) and the Health of Older Adults — China, 2008–2023
Shen C, Chen X. A Systematic Analysis of Early Life Exposure to the Chinese Famine (1959–1961) and the Health of Older Adults — China, 2008–2023. China CDC Weekly 2024, 6: 203-207. PMID: 38532745, PMCID: PMC10961216, DOI: 10.46234/ccdcw2024.041.Peer-Reviewed Original ResearchEarly life circumstancesChinese famineHealth of older adultsLife exposurePublic health practiceLife circumstancesHealth-related sectorsLife course approachEarly life exposuresEnhance public healthHealth practicesOlder adultsHealthy agingHealthPublic healthMeta-analysisOlder ageAging societyStrategic interventionsAgeIndividual environmentsInterventionAdultsMounting evidenceAging process
2023
Trends in Gender and Racial/Ethnic Disparities in Physical Disability and Social Support Among U.S. Older Adults With Cognitive Impairment Living Alone, 2000–2018
Chen S, Zhang H, Underwood B, Wang D, Chen X, Cardinal R. Trends in Gender and Racial/Ethnic Disparities in Physical Disability and Social Support Among U.S. Older Adults With Cognitive Impairment Living Alone, 2000–2018. Innovation In Aging 2023, 7: igad028. PMID: 37223006, PMCID: PMC10202553, DOI: 10.1093/geroni/igad028.Peer-Reviewed Original ResearchCognitive impairmentU.S. older adultsOlder adultsIADL disabilityPhysical disabilityEthnic disparitiesSupport needsRacial/Ethnic DisparitiesSocial supportUnmet support needsEligible peopleInstrumental activitiesDaily livingPoisson regressionBlack respondentsImpairmentDisabilityAdultsBADLU.S. HealthPrevalenceInformal careThe morbidity costs of air pollution through the Lens of Health Spending in China
Zhang X, Zhang X, Liu Y, Zhao X, Chen X. The morbidity costs of air pollution through the Lens of Health Spending in China. Journal Of Population Economics 2023, 36: 1269-1292. DOI: 10.1007/s00148-023-00948-y.Peer-Reviewed Original ResearchSelf-perceived memory is negatively associated with chronic disease awareness: Evidence from blood biomarker data
Lin Z, Fu M, Chen X. Self-perceived memory is negatively associated with chronic disease awareness: Evidence from blood biomarker data. SSM - Population Health 2023, 22: 101361. PMID: 36852376, PMCID: PMC9958050, DOI: 10.1016/j.ssmph.2023.101361.Peer-Reviewed Original ResearchSelf-perceived memoryCognitive abilitiesCognitive misperceptionsChronic disease awarenessImpaired cognitive abilityCognitive measuresDisease awarenessOlder Chinese adultsHealth-related decisionsOlder adultsMemoryOpposite patternLongitudinal studyRetirement Longitudinal StudyBlood biomarker dataNegative associationLow disease awarenessMultivariate logistic regressionSelf-reported diagnosisMisperceptionsTargeted interventionsAdultsIndividualsAwarenessDiabetes status
2022
The whole-of-society approach of mass COVID-19 vaccination in China: a qualitative study
Wang Q, Qu Z, Tu S, Chen X, Hou Z. The whole-of-society approach of mass COVID-19 vaccination in China: a qualitative study. Health Research Policy And Systems 2022, 20: 142. PMID: 36585666, PMCID: PMC9802023, DOI: 10.1186/s12961-022-00947-7.Peer-Reviewed Original ResearchConceptsSociety approachNon-health sectorsKey informant interviewsSemi-structured interviewsGovernment engagementThematic analysis approachPolicy documentsGovernance perspectiveHealth systems frameworkCOVID-19 vaccinationInformant interviewsService deliveryVaccination coverageQualitative studySystem strengtheningHealth workforceBackgroundMany countriesFinancing channelsCOVID-19 pandemicVaccination service deliveryCountriesVaccination systemDigital information systemsOlder adultsImplementation experienceLong-term services and supports and disease management among older Chinese adults in different stages of cognitive impairment
Lin Z, Chen X. Long-term services and supports and disease management among older Chinese adults in different stages of cognitive impairment. The Journal Of The Economics Of Ageing 2022, 23: 100405. DOI: 10.1016/j.jeoa.2022.100405.Peer-Reviewed Original ResearchCognitive impairmentOlder adultsDisease managementDisease preventionPreventive care utilizationNon-communicable diseasesDisease management behaviorsOlder Chinese adultsLong-term care servicesHome-based servicesHypertension awarenessHypertension managementCare utilizationSevere stagesChinese adultsCare servicesAdultsDifferential effectsModest effectDiseaseImpairmentPreventionDifferent stagesLTSSRepresentative dataContribution of life course circumstances to the acceleration of phenotypic and functional aging: A retrospective study
Cao X, Ma C, Zheng Z, He L, Hao M, Chen X, Crimmins EM, Gill TM, Levine ME, Liu Z. Contribution of life course circumstances to the acceleration of phenotypic and functional aging: A retrospective study. EClinicalMedicine 2022, 51: 101548. PMID: 35844770, PMCID: PMC9284373, DOI: 10.1016/j.eclinm.2022.101548.Peer-Reviewed Original ResearchDisease Research CenterDisadvantaged subpopulationsAdulthood circumstancesAlzheimer's Disease Research CenterRetirement Longitudinal StudyFunctional agingLife course circumstancesAdvancing Translational SciencesRetrospective studyChronic diseasesGeneral linear regression modelHealth gapChina HealthBiomarker collectionOlder adultsLater lifeNational InstituteLongitudinal studySubpopulationsLinear regression modelsTranslational scienceRegression modelsChildhoodAdvantaged counterpartsHealthThe Effect of Dual Sensory Impairment and Multimorbidity Patterns on Functional Impairment: A Longitudinal Cohort of Middle-Aged and Older Adults in China
Wang Q, Zhang S, Wang Y, Zhao D, Chen X, Zhou C. The Effect of Dual Sensory Impairment and Multimorbidity Patterns on Functional Impairment: A Longitudinal Cohort of Middle-Aged and Older Adults in China. Frontiers In Aging Neuroscience 2022, 14: 807383. PMID: 35462686, PMCID: PMC9028763, DOI: 10.3389/fnagi.2022.807383.Peer-Reviewed Original ResearchDual sensory impairmentDaily Living ScaleMultimorbidity patternsFunctional impairmentSensory impairmentOlder adultsLiving ScaleCo-existing diseasesRetirement Longitudinal StudyMultimorbidity prevalenceFunctional statusLongitudinal cohortADL limitationsIADL limitationsInstrumental activitiesMultimorbidityRespiratory patternIntegrated careChina HealthImpairmentLongitudinal studyAdultsPrevalenceSelf-report measuresPotent pathwayDifficulty and help with activities of daily living among older adults living alone during the COVID-19 pandemic: a multi-country population-based study
Chen S, Jones LA, Jiang S, Jin H, Dong D, Chen X, Wang D, Zhang Y, Xiang L, Zhu A, Cardinal RN. Difficulty and help with activities of daily living among older adults living alone during the COVID-19 pandemic: a multi-country population-based study. BMC Geriatrics 2022, 22: 181. PMID: 35246064, PMCID: PMC8894568, DOI: 10.1186/s12877-022-02799-w.Peer-Reviewed Original ResearchConceptsHealth system factorsADL assistanceOlder adultsCOVID-19 pandemicPopulation-based studyLongitudinal cohort studyHealth service expendituresSystem factorsCOVID-19Wealth-related inequalitiesHealth-related indicatorsPandemic-related changesCohort studyADL difficultyEligible peopleBackgroundOlder adultsDaily livingAdultsInternational variationConcentration indexService expendituresPandemicDifficulty statusSex gapUnequal responseAmerican Older Adults in COVID-19 Times: Vulnerability Types, Aging Attitudes, and Emotional Responses
Fu M, Guo J, Chen X, Han B, Ahmed F, Shahid M, Zhang Q. American Older Adults in COVID-19 Times: Vulnerability Types, Aging Attitudes, and Emotional Responses. Frontiers In Public Health 2022, 9: 778084. PMID: 35211452, PMCID: PMC8860986, DOI: 10.3389/fpubh.2021.778084.Peer-Reviewed Original ResearchConceptsEmotional responsesNegative emotionsOlder adultsNegative Affect ScheduleLatent class analysisOlder adults' vulnerabilityAmerican Older AdultsPositive emotionsEmotional experienceInternational PositiveOwn agingAdult vulnerabilityVulnerability of individualsEmotionsDual vulnerabilityVulnerable older adultsAttitudesAdultsClass analysisPandemic contextIndividualsVulnerability typesBeingVulnerable counterpartsVulnerabilityEarly-Life Circumstances and Cross-Country Disparities in Cognition Among Older Populations — China, the US, and the EU, 2008–2018
Yan B, Gao S, Dai M, Gill T, Chen X. Early-Life Circumstances and Cross-Country Disparities in Cognition Among Older Populations — China, the US, and the EU, 2008–2018. China CDC Weekly 2022, 4: 1013-1018. PMID: 36483009, PMCID: PMC9709302, DOI: 10.46234/ccdcw2022.205.Peer-Reviewed Original ResearchPromote COVID-19 Vaccination for Older Adults in China
Zang S, Zhang X, Qu Z, Chen X, Hou Z. Promote COVID-19 Vaccination for Older Adults in China. China CDC Weekly 2022, 4: 832-834. PMID: 36284538, PMCID: PMC9547737, DOI: 10.46234/ccdcw2022.173.Peer-Reviewed Original Research
2021
Prevalence of Memory-Related Diagnoses Among U.S. Older Adults With Early Symptoms of Cognitive Impairment
Qian Y, Chen X, Tang D, Kelley AS, Li J. Prevalence of Memory-Related Diagnoses Among U.S. Older Adults With Early Symptoms of Cognitive Impairment. The Journals Of Gerontology Series A 2021, 76: 1846-1853. PMID: 33575783, PMCID: PMC8436977, DOI: 10.1093/gerona/glab043.Peer-Reviewed Original Research
2020
How and to what extent can pensions facilitate increased use of health services by older people: evidence from social pension expansion in rural China
Chen S, Chen X, Law S, Lucas H, Tang S, Long Q, Xue L, Wang Z. How and to what extent can pensions facilitate increased use of health services by older people: evidence from social pension expansion in rural China. BMC Health Services Research 2020, 20: 1008. PMID: 33148248, PMCID: PMC7640495, DOI: 10.1186/s12913-020-05831-0.Peer-Reviewed Original ResearchConceptsHealth service utilizationService utilizationHealth servicesOlder peopleFrequency of outpatientInpatient service useHealthcare-seeking behaviorRetirement Longitudinal StudyProportion of peopleTraditional Chinese medicineHealthcare utilisationService useEconomic burdenInpatient servicesAge groupsAdditional economic burdenChina HealthOlder adultsChinese medicineMethodsUsing dataLongitudinal studyOutpatientsRegression analysisState of healthFuzzy regression discontinuity designLinking early life risk factors to frailty in old age: evidence from the China Health and Retirement Longitudinal Study
Li Y, Xue QL, Odden MC, Chen X, Wu C. Linking early life risk factors to frailty in old age: evidence from the China Health and Retirement Longitudinal Study. Age And Ageing 2020, 49: 208-217. PMID: 31957780, PMCID: PMC7047816, DOI: 10.1093/ageing/afz160.Peer-Reviewed Original ResearchConceptsEarly life risk factorsLife risk factorsRisk factorsChildhood health statusRetirement Longitudinal StudyRisk differenceHealth statusChina HealthOlder ageOlder adultsAbsolute risk differenceCross-sectional studyLongitudinal studyUnfavorable socioeconomic statusLate-life frailtyWorse health conditionsChinese older adultsMiddle-income countriesDevelopment of diseaseHigh riskLower riskRepresentative cohortMultinomial regression modelsHealth conditionsFrailtyHealth inequality among Chinese older adults: The role of childhood circumstances
Yan B, Chen X, Gill TM. Health inequality among Chinese older adults: The role of childhood circumstances. The Journal Of The Economics Of Ageing 2020, 17: 100237. PMID: 32064224, PMCID: PMC7021249, DOI: 10.1016/j.jeoa.2020.100237.Peer-Reviewed Original ResearchHealth-related circumstancesHealth inequalitiesChildhood circumstancesOlder ageSelf-rated healthMultiple health outcomesRetirement Longitudinal StudyChinese older adultsHealth outcomesChina HealthCognitive healthMental healthOlder adultsPhysical healthAnalytic sampleLife course approachLongitudinal studyAgeShapley value decomposition approachPerson's ageHealthCourse approachMortalityHistory survey
2019
Effect of family income on cognition in older adults in China: an instrumental-variables decomposition analysis
Hu H, Si Y, Chen X. Effect of family income on cognition in older adults in China: an instrumental-variables decomposition analysis. The Lancet 2019, 394: s81. DOI: 10.1016/s0140-6736(19)32417-1.Peer-Reviewed Original ResearchIncome-related inequalitiesAdult cognitionIntact mental statusConcentration indexEpisodic memoryFamily incomeInstrumental variablesDecomposition analysisOlder adultsOlder adults' cognitionTax incomeWord recallCognitive measuresCognitive abilitiesCognitive skillsPolicy interventionsTotal investmentRetirement Longitudinal StudyIncomeCognition problemsCognitionFinancial outcomesPolicy makersCausal effectEconomic resourcesAssociations of genetics, behaviors, and life course circumstances with a novel aging and healthspan measure: Evidence from the Health and Retirement Study
Liu Z, Chen X, Gill TM, Ma C, Crimmins EM, Levine ME. Associations of genetics, behaviors, and life course circumstances with a novel aging and healthspan measure: Evidence from the Health and Retirement Study. PLOS Medicine 2019, 16: e1002827. PMID: 31211779, PMCID: PMC6581243, DOI: 10.1371/journal.pmed.1002827.Peer-Reviewed Original ResearchConceptsCoronary artery diseaseArtery diseasePhenotypic agingUS older adultsSelf-reported circumstancesRetirement StudyLife course circumstancesAssociation of geneticMorbidity riskMultivariable associationsPotential policy targetsRetrospective natureAdulthood circumstancesPhenotypic AgeAdulthood adversityGenetic predispositionHealth behaviorsSocioenvironmental circumstancesUS populationOlder adultsPotential interventionsDisadvantaged subpopulationsGenetic riskGenetic scoreUS Health