Local ventromedial hypothalamus glucose perfusion blocks counterregulation during systemic hypoglycemia in awake rats.
Borg MA, Sherwin RS, Borg WP, Tamborlane WV, Shulman GI. Local ventromedial hypothalamus glucose perfusion blocks counterregulation during systemic hypoglycemia in awake rats. Journal Of Clinical Investigation 1997, 99: 361-365. PMID: 9006005, PMCID: PMC507804, DOI: 10.1172/jci119165.Peer-Reviewed Original ResearchConceptsVentromedial hypothalamic nucleusMM D-glucoseControl groupGlucose perfusionHypoglycemic counterregulationSystemic hypoglycemiaNorepinephrine releaseGlucagon secretionCatecholamine concentrationsHypothalamic nucleiAwake ratsHormonal secretionControl animalsHypoglycemiaHormonal responsesPerfusionL glucoseCounterregulationD-glucoseGlucagonRatsSecretionGlucoseAnimalsGlucopenia