Associations of Microvascular Complications With the Risk of Cardiovascular Disease in Type 1 Diabetes.
Gubitosi-Klug R, Gao X, Pop-Busui R, de Boer IH, White N, Aiello LP, Miller R, Palmer J, Tamborlane W, Wallia A, Kosiborod M, Lachin JM, Bebu I. Associations of Microvascular Complications With the Risk of Cardiovascular Disease in Type 1 Diabetes. Diabetes Care 2021, 44: 1499-1505. PMID: 33980605, PMCID: PMC8323173, DOI: 10.2337/dc20-3104.Peer-Reviewed Original ResearchConceptsMajor adverse cardiovascular eventsAlbumin excretion rateNonfatal myocardial infarctionSubsequent cardiovascular diseaseCardiovascular diseaseMicrovascular complicationsMyocardial infarctionMicrovascular diseaseSubsequent riskDCCT/EDIC cohortTraditional CVD risk factorsUrinary albumin excretion rateAdvanced microvascular diseaseSubclinical myocardial infarctionAdverse cardiovascular eventsCoronary artery revascularizationCVD risk factorsGlomerular filtration rateSignificant macular edemaType 1 diabetesProportional hazards modelRetinal fundus photographyArtery revascularizationComplications StudyNonfatal stroke